Separation of Thyroxine-Binding Proteins in Human Serum at pH 7.4. II. Effect of pH and Temperature on the Binding Capacities of Thyroxine-Binding Globulin (TBG) and Thyroxine-Binding Prealbumin (TBPA)

1971 ◽  
Vol 33 (4) ◽  
pp. 699-708 ◽  
Author(s):  
PAUL J. DAVIS ◽  
ROBERT I. GREGERMAN
Keyword(s):  
Human Serum ◽  
Binding Proteins ◽  
Effect Of Ph ◽  
Thyroxine Binding Globulin

ENDOCRINE CHANGES BEFORE AND AFTER THE MENARCHE

1973 ◽  
Vol 74 (4) ◽  
pp. 685-694 ◽  
Author(s):  
B.-A. Lamberg ◽  
R.-L. Kantero ◽  
P. Saarinen ◽  
O. Widholm
Keyword(s):  
Binding Proteins ◽  
Maturation Process ◽  
Hormone Binding ◽  
Maximal Level ◽  
Continuous Increase ◽  
Mean Values ◽  
Thyroxine Binding Globulin ◽  
Before And After ◽  
Free Thyroxine Index ◽  
Level 1

ABSTRACT In an endocrine survey of healthy girls aged 8 to 20 years before and after the menarche, the serum thyroxine (T4), uptake of triiodothyronine by Sephadex (T3U), and the binding capacities of thyroxine binding globulin (TBG) and pre-albumin (TBPA) were measured, and a free thyroxine index (FTI = T4 × T3U) was calculated. The subjects were grouped according to skeletal age (SA) until the menarche and after this in the post-menarcheal age (PMA), expressed in years. T4 and FTI increased concomitantly and reached peak values of 8.40 μg/100 ml and 8.40, respectively, at 2–3 years PMA. The corresponding mean values for post-menarcheal girls (7.74 μg/100 ml and 7.51) differed statistically significantly from the means before the menarche (7.03 μg/ 100 ml and 6.75). The TBG remained virtually unchanged during the whole period, whereas the TBPA showed a continuous increase and reached a maximal level 1–2 years after the menarche. The maturation process in girls in some way involves an increase in the total and free T4 level which is not dependent on hormone binding proteins.

Activin-binding proteins in human serum and follicular fluid.

1992 ◽  
Vol 74 (6) ◽  
pp. 1320-1324
Author(s):  
A L Schneyer ◽  
D A O'Neil ◽  
W F Crowley
Keyword(s):  
Human Serum ◽  
Follicular Fluid ◽  
Binding Proteins

TRH (Thyroid-Releasing Hormone) Tests

1984 ◽  
Vol 6 (6) ◽  
pp. 189-190
Keyword(s):  
Binding Proteins ◽  
Elevated Serum ◽  
Graves Disease ◽  
Base Line ◽  
Trh Test ◽  
Thyroxine Binding Globulin ◽  
Serum Thyroxine ◽  
Free Thyroxine Index ◽  
Serum T4 ◽  
Line Test

I have read with great interest "Goiter in Children" by Foley (PIR 1984;5:259). The author stated: "In patients with thyromegaly and mild symptoms of hyperthyroidism, a TRH test will help to discriminate hyperthyroxemia secondary to increased or abnormal serum thyroxine binding proteins from early Graves disease, factitious hyperthyroidism, toxic thyroiditis, and TSH-mediated hyperthyroidism." I would suggest the use of a triiodothyronine (T3) resin uptake as a base-line test. An elevated serum thyroxine (T4) value in conjunction with a diminished T3 resin uptake suggests thyroxine-binding globulin (TBG) excess, which can be confirmed by specific quantitation of TBG. Patients with familial dysalbuminemic hyperthyroxinemia (FDH) have elevated levels of serum T4 and free thyroxine index (FT4l) values but normal T3 resin uptake and TBG levels.

Identification of staphylococcal lipoteichoic acid-binding proteins in human serum by high-resolution LTQ-Orbitrap mass spectrometry

2012 ◽  
Vol 50 (3) ◽  
pp. 177-183 ◽  
Author(s):  
Kyoung-Soon Jang ◽  
Jung Eun Baik ◽  
Seok-Seong Kang ◽  
Jun Ho Jeon ◽  
Seulggie Choi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Human Serum ◽  
Binding Proteins ◽  
Lipoteichoic Acid ◽  
Orbitrap Mass Spectrometry
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