Increase of Serum Growth Hormone Concentration following Thyrotropin-Releasing Hormone Injection in Patients with Acromegaly or Gigantism

1972 ◽  
Vol 35 (1) ◽  
pp. 97-100 ◽  
Author(s):  
MINORU IRIE ◽  
TOSHIO TSUSHIMA
Keyword(s):  
Growth Hormone ◽  
Thyrotropin Releasing Hormone ◽  
Hormone Concentration ◽  
Serum Growth Hormone ◽  
Releasing Hormone ◽  
Growth Hormone Concentration ◽  
Hormone Injection ◽  
Serum Growth Hormone Concentration

Effect of Chlorpromazine on Serum Growth-Hormone Concentration in Man

1971 ◽  
Vol 284 (2) ◽  
pp. 72-74 ◽  
Author(s):  
Lawrence Sherman ◽  
Sooseng Kim ◽  
Fred Benjamin ◽  
Howard D. Kolodny
Keyword(s):  
Growth Hormone ◽  
Hormone Concentration ◽  
Serum Growth Hormone ◽  
Growth Hormone Concentration ◽  
Serum Growth Hormone Concentration

Increased Serum Growth Hormone Concentration in Feline Hypertrophic Cardiomyopathy

1992 ◽  
Vol 6 (6) ◽  
pp. 320-324 ◽  
Author(s):  
Mark D. Kittleson ◽  
Paul D. Pion ◽  
Laura A. DeLellis ◽  
Yousry Mekhamer ◽  
Noel Dybdal ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hypertrophic Cardiomyopathy ◽  
Hormone Concentration ◽  
Serum Growth Hormone ◽  
Growth Hormone Concentration ◽  
Serum Growth Hormone Concentration

scholarly journals Nocturnal Serum Growth Hormone Concentration is not Augmented by Short-Term Testosterone Infusion in Pubertal Boys

1989 ◽  
Vol 26 (4) ◽  
pp. 320-324 ◽  
Author(s):  
Carol M Foster ◽  
Nancy J Hopwood ◽  
Jeanne M Hassing ◽  
Paula M Hale ◽  
Tarina Mendes ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Concentration ◽  
Short Term ◽  
Serum Growth Hormone ◽  
Growth Hormone Concentration ◽  
Pubertal Boys ◽  
Serum Growth Hormone Concentration

Inhibition of dopamine-induced release of growth hormone by thyrotropin-releasing hormone.

1977 ◽  
Vol 233 (5) ◽  
pp. E430
Author(s):  
R A Steiner ◽  
P Illner ◽  
P Marques ◽  
D Williams ◽  
L Shen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Growth Hormone ◽  
Intravenous Infusion ◽  
Serum Insulin ◽  
Thyrotropin Releasing Hormone ◽  
Adolescent Male ◽  
Serum Growth Hormone ◽  
Releasing Hormone ◽  
Effective Doses ◽  
Serum Gh

The effects of thyrotropin-releasing hormone (TRH) and dopamine (DA) on serum growth hormone (GH) levels were examined in the adolescent male baboon. Intravenously administered DA (40 microgram/kg-min-1 for 20 min) raised serum GH and glucose and lowered serum insulin concentrations but caused no increase in blood pressure. Concomitant intravenous infusion of TRH at 2 doses (96 ng/kg-min-1 and 40 microgram/kg-min-1 for 20 min) blocked the DA-induced increase in serum GH. The relatively low effective doses of TRH used to suppress the DA-induced GH increase suggest an interaction with catecholamines at the hypothalamic and/or pituitary to influence GH release.

scholarly journals Response of growth hormone to various doses of growth hormone releasing factor and thyrotropin releasing hormone administered separately and in combination to dairy calves

1991 ◽  
Vol 71 (4) ◽  
pp. 1045-1052 ◽  
Author(s):  
Peter Løvendahl ◽  
John A. Woolliams ◽  
Patrick A. Sinnett-Smith
Keyword(s):  
Growth Hormone ◽  
Area Under The Curve ◽  
Multiplicative Model ◽  
Thyrotropin Releasing Hormone ◽  
Dairy Calves ◽  
Serum Growth Hormone ◽  
Growth Hormone Releasing Factor ◽  
Releasing Hormone ◽  
The Mean ◽  
Multiplicative Effects

Doses of growth hormone releasing factor (GRF) and thyrotropin releasing hormone (TRH) and combinations of these were administered by intravenous injection to six calves aged 155 ± 3 days and weighing 136 ± 16 kg. Injections were at 09:00, 12:00 and 15:00 h on 4 days, and doses were 0, 15, 30 and 60 pmol GRF kg−1 and 0, 275, 550 and 1100 pmol TRH kg−1, with GRF plus TRH at all combinations of these doses. Response of serum growth hormone (GH) was measured as the mean at 5, 10, 15 and 20 min following injection (PEAK) and the area under the curve during 0–60 min (AUC). The correlation between PEAK and AUC was 0.98. The variation in PEAK was related to GH prior to injection and to PEAK 3 h earlier. Separate multiplicative effects for each secretagogue were fitted, with the effects related to the logarithm of dose. Doubling the dose increased PEAK by 1.46-fold following GRF (P < 0.05) and 1.25-fold following TRH (P < 0.05). There was no evidence that the results for either secretagogue were affected by the presence or absence of the other. This multiplicative model provides a description of the synergy between these secretagogues. Key words: GH-release, GRF, TRH, calves, dose response

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