scholarly journals Practice guideline summary: Use of fMRI in the presurgical evaluation of patients with epilepsy

Neurology ◽  
2017 ◽  
Vol 88 (4) ◽  
pp. 395-402 ◽  
Author(s):  
Jerzy P. Szaflarski ◽  
David Gloss ◽  
Jeffrey R. Binder ◽  
William D. Gaillard ◽  
Alexandra J. Golby ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Verbal Memory ◽  
Medial Temporal Lobe ◽  
Case Reports ◽  
Data Extraction ◽  
General Level ◽  
Temporal Epilepsy ◽  
Language Functions ◽  
Temporal Lobe Resection ◽  
Meta Analyses

Objective:To assess the diagnostic accuracy and prognostic value of functional MRI (fMRI) in determining lateralization and predicting postsurgical language and memory outcomes.Methods:An 11-member panel evaluated and rated available evidence according to the 2004 American Academy of Neurology process. At least 2 panelists reviewed the full text of 172 articles and selected 37 for data extraction. Case reports, reports with <15 cases, meta-analyses, and editorials were excluded.Results and recommendations:The use of fMRI may be considered an option for lateralizing language functions in place of intracarotid amobarbital procedure (IAP) in patients with medial temporal lobe epilepsy (MTLE; Level C), temporal epilepsy in general (Level C), or extratemporal epilepsy (Level C). For patients with temporal neocortical epilepsy or temporal tumors, the evidence is insufficient (Level U). fMRI may be considered to predict postsurgical language deficits after anterior temporal lobe resection (Level C). The use of fMRI may be considered for lateralizing memory functions in place of IAP in patients with MTLE (Level C) but is of unclear utility in other epilepsy types (Level U). fMRI of verbal memory or language encoding should be considered for predicting verbal memory outcome (Level B). fMRI using nonverbal memory encoding may be considered for predicting visuospatial memory outcomes (Level C). Presurgical fMRI could be an adequate alternative to IAP memory testing for predicting verbal memory outcome (Level C). Clinicians should carefully advise patients of the risks and benefits of fMRI vs IAP during discussions concerning choice of specific modality in each case.

Timely Revisit of Proprioceptive Deficits in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-Analysis

2021 ◽  
pp. 219256822110668
Author(s):  
Kenney K. L. Lau ◽  
Karlen K. P. Law ◽  
Kenny Y. H. Kwan ◽  
Jason P. Y. Cheung ◽  
Kenneth M. C. Cheung ◽  
...  
Keyword(s):  
Systematic Review ◽  
Adolescent Idiopathic Scoliosis ◽  
Idiopathic Scoliosis ◽  
Case Reports ◽  
Data Extraction ◽  
Meta Analysis ◽  
Detection Threshold ◽  
Mean Difference ◽  
Case Control Studies ◽  
Meta Analyses

Study Design Systematic review and meta-analysis Objectives The present review aimed to summarize the evidence regarding differences in proprioception between children with and without adolescent idiopathic scoliosis (AIS). Methods Seven electronic databases were searched from their inception to April 10, 2021. Articles were included if they involved: (1) AIS patients aged between 10 and 18 years, (2) measurements of proprioceptive abilities, and (3) comparisons with non-AIS controls. Animal studies, case reports, commentaries, conference proceedings, research protocols, and reviews were excluded. Two reviewers independently conducted literature screening, data extraction, risks of bias assessments, and quality of evidence evaluations. Relevant information was pooled for meta-analyses. Results From 432 identified citations, 11 case-control studies comprising 1121 participants were included. The meta-analyses showed that AIS participants displayed proprioceptive deficits as compared to non-AIS controls. Moderate evidence supported that AIS participants showed significantly larger repositioning errors than healthy controls (pooled mean difference = 1.27 degrees, P < .01). Low evidence substantiated that AIS participants had significantly greater motion detection threshold (pooled mean difference = 1.60 degrees, P < .01) and abnormal somatosensory evoked potentials (pooled mean difference = .36 milliseconds, P = .01) than non-AIS counterparts. Conclusions Consistent findings revealed that proprioceptive deficits occurred in AIS patients. Further investigations on the causal relationship between AIS and proprioception, and the identification of the subgroup of AIS patients with proprioceptive deficit are needed.

scholarly journals Decision-making impairments following insular and medial temporal lobe resection for drug-resistant epilepsy

2016 ◽  
pp. nsw152 ◽  
Author(s):  
Zorina Von Siebenthal ◽  
Olivier Boucher ◽  
Isabelle Rouleau ◽  
Maryse Lassonde ◽  
Franco Lepore ◽  
...  
Keyword(s):  
Decision Making ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Drug Resistant ◽  
Temporal Lobe Resection ◽  
Drug Resistant Epilepsy

scholarly journals Preserved verbal memory function in left medial temporal pathology involves reorganisation of function to right medial temporal lobe

NeuroImage ◽  
2003 ◽  
Vol 20 ◽  
pp. S112-S119 ◽  
Author(s):  
Mark P Richardson ◽  
Bryan A Strange ◽  
John S Duncan ◽  
Raymond J Dolan
Keyword(s):  
Temporal Lobe ◽  
Verbal Memory ◽  
Medial Temporal Lobe ◽  
Memory Function

scholarly journals Superior Verbal Memory Outcome After Stereotactic Laser Amygdalohippocampotomy

2021 ◽  
Vol 12 ◽  
Author(s):  
Daniel L. Drane ◽  
Jon T. Willie ◽  
Nigel P. Pedersen ◽  
Deqiang Qiu ◽  
Natalie L. Voets ◽  
...  
Keyword(s):  
Laser Ablation ◽  
Temporal Lobe ◽  
Verbal Memory ◽  
Mesial Temporal Sclerosis ◽  
Open Resection ◽  
Memory Decline ◽  
Exact Test ◽  
Fisher's Exact Test ◽  
Fisher’S Exact Test ◽  
Temporal Lobe Resection

Objective: To evaluate declarative memory outcomes in medically refractory epilepsy patients who underwent either a highly selective laser ablation of the amygdalohippocampal complex or a conventional open temporal lobe resection.Methods: Post-operative change scores were examined for verbal memory outcome in epilepsy patients who underwent stereotactic laser amygdalohippocampotomy (SLAH: n = 40) or open resection procedures (n = 40) using both reliable change index (RCI) scores and a 1-SD change metric.Results: Using RCI scores, patients undergoing open resection (12/40, 30.0%) were more likely to decline on verbal memory than those undergoing SLAH (2/40 [5.0%], p = 0.0064, Fisher's exact test). Patients with language dominant procedures were much more likely to experience a significant verbal memory decline following open resection (9/19 [47.4%]) compared to laser ablation (2/19 [10.5%], p = 0.0293, Fisher's exact test). 1 SD verbal memory decline frequently occurred in the open resection sample of language dominant temporal lobe patients with mesial temporal sclerosis (8/10 [80.0%]), although it rarely occurred in such patients after SLAH (2/14, 14.3%) (p = 0.0027, Fisher's exact test). Memory improvement occurred significantly more frequently following SLAH than after open resection.Interpretation: These findings suggest that while verbal memory function can decline after laser ablation of the amygdalohippocampal complex, it is better preserved when compared to open temporal lobe resection. Our findings also highlight that the dominant hippocampus is not uniquely responsible for verbal memory. While this is at odds with our simple and common heuristic of the hippocampus in memory, it supports the findings of non-human primate studies showing that memory depends on broader medial and lateral TL regions.

scholarly journals Visual memory test equal to commonly used verbal memory test in predicting tau in the medial temporal lobe

2021 ◽  
Vol 17 (S6) ◽  
Author(s):  
Nina Margherita Poltronetti ◽  
Jaime Fernandez Arias ◽  
Vanessa Pallen ◽  
Firoza Z Lussier ◽  
Joseph Therriault ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Verbal Memory ◽  
Visual Memory ◽  
Medial Temporal Lobe ◽  
Memory Test

Predicting verbal memory decline following temporal lobe resection for epilepsy

2019 ◽  
Vol 140 (5) ◽  
pp. 312-319 ◽  
Author(s):  
Sofia Ljunggren ◽  
Lena Andersson‐Roswall ◽  
Henrik Imberg ◽  
Hans Samuelsson ◽  
Kristina Malmgren
Keyword(s):  
Temporal Lobe ◽  
Verbal Memory ◽  
Memory Decline ◽  
Temporal Lobe Resection

Erratum to “Auditory/visual duration bisection in patients with left or right medial-temporal lobe resection” [Brain and Cognition 58 (2005) 119–124]

2006 ◽  
Vol 60 (1) ◽  
pp. 105
Author(s):  
Manuela Melgire ◽  
Richard Ragot ◽  
Séverine Samson ◽  
Trevor B. Penney ◽  
Warren H. Meck ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Temporal Lobe Resection

scholarly journals A Meta-Analysis of the Prevalence of Cardiac Valvulopathy in Patients With Hyperprolactinemia Treated With Cabergoline

2018 ◽  
Vol 104 (2) ◽  
pp. 523-538 ◽  
Author(s):  
Craig E Stiles ◽  
Eugene T Tetteh-Wayoe ◽  
Jonathan P Bestwick ◽  
Richard P Steeds ◽  
William M Drake
Keyword(s):  
Tricuspid Regurgitation ◽  
Clinical Symptoms ◽  
Single Case ◽  
Case Reports ◽  
Data Extraction ◽  
Meta Analysis ◽  
Pituitary Tumors ◽  
Inclusion Criteria ◽  
Case Control Studies ◽  
Meta Analyses

Abstract Context Cabergoline is first-line treatment for most patients with lactotrope pituitary tumors and hyperprolactinemia. Its use at high dosages in Parkinson disease (PD) has largely been abandoned because of its association with the development of a characteristic restrictive cardiac valvulopathy. Whether similar valvular changes occur in patients receiving lower dosages for treatment of hyperprolactinemia is unclear, although stringent regulatory recommendations for echocardiographic screening exist. Objective To conduct a meta-analysis exploring any link between the use of cabergoline for the treatment of hyperprolactinemia and clinically significant cardiac valvulopathy. Data Sources Full-text articles published through January 2017 were found via PubMed and selected according to strict inclusion criteria. Study Selection All case-control studies were included where patients had received ≥6 months of cabergoline treatment for hyperprolactinemia. Single case reports, previous meta-analyses, review articles, and articles pertaining solely to PD were excluded. Of 76 originally selected studies, 13 met inclusion criteria. Data Extraction Desired data were compiled and extracted from articles by independent observers. Each also independently graded article quality (bias) and met to reach consensus. Data Synthesis More tricuspid regurgitation was observed (OR 3.74; 95% CI, 1.79 to 7.8; P &lt; 0.001) in the cabergoline-treated patients compared with controls. In no patient was tricuspid valve dysfunction diagnosed as a result of clinical symptoms. There was no significant increase in any other valvulopathy. Conclusions Treatment with low-dose cabergoline in hyperprolactinemia appears to be associated with an increased prevalence of tricuspid regurgitation. The clinical significance of this finding is unclear and warrants further investigation.

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