Clinical and magnetic resonance imaging in optic neuritis

Neurology ◽  
1991 ◽  
Vol 41 (1) ◽  
pp. 15-15 ◽  
Author(s):  
L. Jacobs ◽  
F. E. Munschauer ◽  
S. E. Kaba
2021 ◽  
Vol 15 ◽  
Author(s):  
Ke Song ◽  
Yong Wang ◽  
Mei-Xia Ren ◽  
Jiao Li ◽  
Ting Su ◽  
...  

Background: Using resting-state functional connectivity (rsFC), we investigated alternations in spontaneous brain activities reflected by functional connectivity density (FCD) in patients with optic neuritis (ON).Methods: We enrolled 28 patients with ON (18 males, 10 females) and 24 healthy controls (HCs; 16 males, 8 females). All subjects underwent functional magnetic resonance imaging (fMRI) in a quiet state to determine the values of rsFC, long-range FCD (longFCD), and short-range FCD (IFCD). Receiver operating characteristic (ROC) curves were generated to distinguish patients from HCs.Results: The ON group exhibited obviously lower longFCD values in the left inferior frontal gyrus triangle, the right precuneus and the right anterior cingulate, and paracingulate gyri/median cingulate and paracingulate gyri. The left median cingulate and paracingulate gyri and supplementary motor area (SMA) were also significantly lower. Obviously reduced IFCD values were observed in the left middle temporal gyrus/angular gyrus/SMA and right cuneus/SMA compared with HCs.Conclusion: Abnormal neural activities were found in specific brain regions in patients with ON. Specifically, they showed significant changes in rsFC, longFCD, and IFCD values. These may be useful to identify the specific mechanism of change in brain function in ON.


2000 ◽  
Vol 10 (4) ◽  
pp. 209-215 ◽  
Author(s):  
Erhan Ergene ◽  
Frederick W Rupp ◽  
Clifford R. Qualls ◽  
Corey C. Ford

2005 ◽  
Vol 11 (4) ◽  
pp. 492-494 ◽  
Author(s):  
E T Lim ◽  
T Berger ◽  
M Reindl ◽  
C M Dalton ◽  
K Fernando ◽  
...  

This study investigates whether the presence of serum and plasma anti-myelin oligodendrocyte glycoprotein (MOG) and anti-myelin basic protein (MBP) in patients presenting with a clinically isolated syndrome compatible with demyelination (CIS) predicts early conversion to multiple sclerosis (MS). Forty-seven patients with CIS (46 with optic neuritis) had anti-MOG and anti-MBP antibodies analysed at baseline, and clinical and magnetic resonance imaging assessments. There was no evidence that the MS status based on either the McDonald or Poser criteria relates to the antibody status.


1986 ◽  
Vol 104 (10) ◽  
pp. 1486-1488 ◽  
Author(s):  
K. Johns ◽  
P. Lavin ◽  
J. H. Elliot ◽  
C. L. Partain

2019 ◽  
Vol 54 (2) ◽  
pp. 242-246 ◽  
Author(s):  
Lulu L.C.D. Bursztyn ◽  
Lindsey B. De Lott ◽  
Myria Petrou ◽  
Wayne T. Cornblath

The Lancet ◽  
1986 ◽  
Vol 327 (8496) ◽  
pp. 1490-1491 ◽  
Author(s):  
D.H Miller ◽  
G Johnson ◽  
W.I Mcdonald ◽  
D Macmanus ◽  
E.P.G.H Duboulay ◽  
...  

Neurology ◽  
1988 ◽  
Vol 38 (2) ◽  
pp. 175-175 ◽  
Author(s):  
D. H. Miller ◽  
M. R. Newton ◽  
J. C. van der Poel ◽  
E. P. G. H. du Boulay ◽  
A. M. Halliday ◽  
...  

1998 ◽  
Vol 155 (1) ◽  
pp. 44-49 ◽  
Author(s):  
Hayrettin Tumani ◽  
Wallace W Tourtellotte ◽  
James B Peter ◽  
Klaus Felgenhauer ◽  
The Optic Neuritis Study Group

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