Multimodal Prehabilitation During Neoadjuvant Therapy Prior to Esophagogastric Cancer Resection: Effect on Cardiopulmonary Exercise Test Performance, Muscle Mass and Quality of Life—A Pilot Randomized Clinical Trial

Author(s):  
Sophie K. Allen ◽  
Vanessa Brown ◽  
Daniel White ◽  
David King ◽  
Julie Hunt ◽  
...  
2019 ◽  
Vol 68 ◽  
pp. 02009
Author(s):  
Rudolfs Ceseiko ◽  
Signe Tomsone ◽  
Laura Majevska ◽  
Aivars Vetra

Breast cancer treatment may cause unfavourable side effects that directly or indirectly influence the cardio-respiratory capacity among breast cancer survivors, thus affecting physical functioning and the quality of life. Mounting evidence supports that Maximal oxygen uptake (VO2max) is a strong predictor of all-cause mortality and cardiovascular disease, and low VO2max is associated with increased mortality from breast cancer. The aim of the study was to measure cardio-respiratory fitness in breast cancer survivors and determine to what extent VO2max levels are lower compared with healthy counterparts from population. The study included 11 women with a history of breast cancer, the average time after breast surgery being 2–3 years. Aerobic capacity was determined by the Cardiopulmonary exercise test. HUNT3 study was used to define aerobic capacity for healthy women in population. Mean Age for participatns 50 ± 4 years (M ± SD). The comparison of the results from Cardiopulmonary exercise test indicated that breast cancer survivors display VO2max values significantly lower 27.1 ml/kg/min (27%) than healthy counterparts from population, i.e., 34.4 ml/kg/min (P = 0.001). Recognizing the increasing number of breast cancer patients worldwide and the physical reconditioning among the survivors, aerobic exercise training is suitable for improving cardio-respiratory health, functionality, and quality of life.


2021 ◽  
Vol 91 (1) ◽  
Author(s):  
Maurizio Bussotti ◽  
Marinella Sommaruga ◽  
Patrycja Krasinska ◽  
Laura Adelaide Dalla Vecchia

A 42-year-old woman affected by pulmonary atresia came to our attention complaining of dyspnea and fatigue for minimal efforts with important desaturation. After assessing her basal functional capacity with a cardiopulmonary exercise test, the patient was enrolled in an extremely individualized rehabilitation program, which entailed a discreet improvement in the quality of life indices, in the absence of side effects. This paper shows that even patients with extremely severe forms of congenital heart disease, when clinical stable, can undergone a tailored cardiorespiratory rehabilitation program. This must be carried out in a monitored environment and under the supervision of expert personnel.


Sign in / Sign up

Export Citation Format

Share Document