scholarly journals The Effects of a Novel Cyclohexane Dicarboximide Derivative, ST-6, on Hypoxia/Reoxygenation Injury in Perfused Rat Heart.

2000 ◽  
Vol 23 (6) ◽  
pp. 712-716 ◽  
Author(s):  
Satoshi TAKEO ◽  
Kouichi TANONAKA ◽  
Hiroshi KAJIWARA ◽  
Keiko MIYAKE ◽  
Fujio ANTOKU ◽  
...  
Keyword(s):  
Rat Heart ◽  
Perfused Rat Heart ◽  
Reoxygenation Injury ◽  
Hypoxia Reoxygenation

HS-1793, a recently developed resveratrol analogue protects rat heart against hypoxia/reoxygenation injury via attenuating mitochondrial damage

2013 ◽  
Vol 23 (14) ◽  
pp. 4225-4229 ◽  
Author(s):  
Seung Hun Jeong ◽  
Tran My Hanh ◽  
Hyoung Kyu Kim ◽  
Sung Ryul Lee ◽  
In-Sung Song ◽  
...  
Keyword(s):  
Rat Heart ◽  
Mitochondrial Damage ◽  
Reoxygenation Injury ◽  
Hypoxia Reoxygenation

Does inducible NOS have a protective role against hypoxia/reoxygenation injury in rat heart?

2011 ◽  
Vol 20 (1) ◽  
pp. e17-e25 ◽  
Author(s):  
Alma Rus ◽  
Maria Luisa del Moral ◽  
Francisco Molina ◽  
Maria Angeles Peinado
Keyword(s):  
Rat Heart ◽  
Protective Role ◽  
Reoxygenation Injury ◽  
Inducible Nos ◽  
Hypoxia Reoxygenation

scholarly journals The influence of 2-aminoethoxydiphenyl borate on the electrical activity of the rat heart under hypoxia/reoxygenation conditions

2019 ◽  
Author(s):  
Elena Kharkovskaya ◽  
Grigory V. Osipov ◽  
Irina V. Mukhina
Keyword(s):  
Electrical Activity ◽  
Rat Heart ◽  
Vascular Function ◽  
Mapping Method ◽  
Isolated Rat Heart ◽  
Calcium Currents ◽  
Reoxygenation Injury ◽  
Isolated Rat ◽  
Hypoxia Reoxygenation ◽  
Aminoethoxydiphenyl Borate

AbstractThe aim of the study was to apply the multi-electrode mapping method to investigate the effect of 2-aminoethoxydiphenyl borate (2-apb) on the electrical activity and vessels of the isolated rat heart under hypoxia/reoxygenation injury (H/R). To date, the ability to influence on the calcium currents and condition of gap junctions has been shown for 2-apb. Changes in the intracellular calcium concentration in the heart play the pivotal role in the development of H/R.As a result, it was shown that 2-apb influences on the myocardial conduction velocity, sinus rhythm and coronary blood flow in the isolated rat heart. 2-apb caused heart fibrillation during normoxia but not under hypoxia, and attenuated the effect of the H/R on heart rate and vascular function.

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