The Relationship Between Accelerometer-measured Sedentary Behaviors And Physical Activity Energy Expenditure Measured By Doubly-labeled Water

2016 ◽  
Vol 48 ◽  
pp. 548
Author(s):  
Stephanie E. Bonn ◽  
Eric B. Rimm ◽  
Charles E. Matthews ◽  
Jennifer Rood ◽  
Junaidah B. Barnett ◽  
...  
2007 ◽  
Vol 102 (5) ◽  
pp. 1921-1926 ◽  
Author(s):  
P. W. Franks ◽  
R. J. F. Loos ◽  
S. Brage ◽  
S. O'Rahilly ◽  
N. J. Wareham ◽  
...  

Leptin regulates a constellation of neuroendocrine processes that control energy homeostasis. The infusion of leptin in rodents lacking endogenous leptin promotes physical activity energy expenditure (PAEE) and improves insulin signaling, whereas hyperleptinemia is associated with physical inactivity and insulin resistance (IR). We tested whether baseline leptin levels predict changes in PAEE and IR over time, independent of obesity. We also assessed whether the relationship between leptin and change in IR is mediated by PAEE. The population consisted of 288 nondiabetic UK Caucasian adults (mean age: 49.4 yr; SD: 0.7 yr), in whom leptin, insulin, glucose, PAEE (via heart rate monitoring with individual calibration by indirect calorimetry), and anthropometric characteristics had been measured at baseline and 5 yr later. In linear regression models, baseline leptin levels inversely predicted follow-up PAEE ( P = 0.033). On average, individuals with low leptin levels (below sex-specific median) increased their daily activity 35% more during the 5-yr follow-up period than those with above-median leptin levels. Baseline leptin level also predicted worsening IR (fasting, 30-min, and 2-h insulins, and homeostasis model assessment-IR; all P < 0.01). Associations were independent of potential confounders, such as adiposity, age, and sex. Including baseline PAEE as a cofactor in the leptin-insulin models reduced the strength (1–4% reduction) and significance of the associations, suggesting that PAEE mediates the leptin-insulin relationships. Hyperleptinemia predicts a relative decline in PAEE and worsening insulin resistance, possibly via shared molecular pathways.


1998 ◽  
Vol 85 (3) ◽  
pp. 1063-1069 ◽  
Author(s):  
Raymond D. Starling ◽  
Michael J. Toth ◽  
William H. Carpenter ◽  
Dwight E. Matthews ◽  
Eric T. Poehlman

Determinants of daily energy needs and physical activity are unknown in free-living elderly. This study examined determinants of daily total energy expenditure (TEE) and free-living physical activity in older women ( n = 51; age = 67 ± 6 yr) and men ( n = 48; age = 70 ± 7 yr) by using doubly labeled water and indirect calorimetry. Using multiple-regression analyses, we predicted TEE by using anthropometric, physiological, and physical activity indexes. Data were collected on resting metabolic rate (RMR), body composition, peak oxygen consumption (V˙o 2 peak), leisure time activity, and plasma thyroid hormone. Data adjusted for body composition were not different between older women and men, respectively (in kcal/day): TEE, 2,306 ± 647 vs. 2,456 ± 666; RMR, 1,463 ± 244 vs. 1,378 ± 249; and physical activity energy expenditure, 612 ± 570 vs. 832 ± 581. In a subgroup of 70 women and men, RMR andV˙o 2 peakexplained approximately two-thirds of the variance in TEE ( R 2 = 0.62; standard error of the estimate = ±348 kcal/day). Crossvalidation of this equation in the remaining 29 women and men was successful, with no difference between predicted and measured TEE (2,364 ± 398 and 2,406 ± 571 kcal/day, respectively). The strongest predictors of physical activity energy expenditure ( P < 0.05) for women and men were V˙o 2 peak( r = 0.43), fat-free mass ( r = 0.39), and body mass ( r = 0.34). In summary, RMR andV˙o 2 peak are important independent predictors of energy requirements in the elderly. Furthermore, cardiovascular fitness and fat-free mass are moderate predictors of physical activity in free-living elderly.


1999 ◽  
Vol 86 (6) ◽  
pp. 2090-2096 ◽  
Author(s):  
Raymond D. Starling ◽  
Dwight E. Matthews ◽  
Philip A. Ades ◽  
Eric T. Poehlman

We compared the accuracy of two physical activity recall questionnaires and a motion detector in 45- to 84-yr-old women ( n = 35) and men ( n = 32), using doubly labeled water (DLW) in conjunction with indirect calorimetry as the criterion measure. Subjects were administered the Yale Physical Activity Survey (YPAS) and Minnesota Leisure Time Physical Activity Questionnaire (LTA). Physical activity energy expenditure was determined over a 10-day period by using a Caltrac uniaxial accelerometer and DLW in conjunction with indirect calorimetry. In older women, Minnesota LTA (386 ± 228 kcal/day) and Caltrac (379 ± 162 kcal/day) underestimated physical activity by ∼55% compared with DLW (873 ± 244 kcal/day). No difference was observed between daily physical activity measured by the YPAS (863 ± 447 kcal/day) and DLW in older women. In older men, Minnesota LTA (459 ± 288 kcal/day) and Caltrac (554 ± 242 kcal/day) underestimated daily physical activity by ∼50–60% compared with DLW (1,211 ± 429 kcal/day). No difference was found between physical activity measured by the YPAS (1,107 ± 612 kcal/day) and DLW in older men. Despite no difference in mean physical activity levels between YPAS and DLW in women and men, Bland and Altman ( Lancet 1: 307–310, 1986) analyses demonstrated poor concordance between DLW and YPAS (i.e., limits of agreement = −1,310–1,518 kcal/day). Our data suggest that the Minnesota LTA recall and Caltrac uniaxial accelerometer may significantly underestimate free-living daily physical activity energy expenditure in older women and men. Although the YPAS compares favorably with DLW on a group basis, its use as a proxy measure of individual daily physical activity energy expenditure may be limited in older women and men.


2014 ◽  
Vol 46 ◽  
pp. 791-792
Author(s):  
Tom E. Nightingale ◽  
Jean-Philippe Walhin ◽  
Dylan Thompson ◽  
James L.J. Bilzon

2002 ◽  
Vol 44 (1) ◽  
pp. 8-14 ◽  
Author(s):  
Tadaaki Wakui ◽  
Setsuko Shirono ◽  
Seiichiro Takahashi ◽  
Takae Fujimura ◽  
Noriaki Harada

Sensors ◽  
2015 ◽  
Vol 15 (3) ◽  
pp. 6133-6151 ◽  
Author(s):  
Mikkel Schneller ◽  
Mogens Pedersen ◽  
Nidhi Gupta ◽  
Mette Aadahl ◽  
Andreas Holtermann

Sign in / Sign up

Export Citation Format

Share Document