scholarly journals Objectively-Measured Physical Activity in Breast Cancer Patients Undergoing Chemotherapy

2019 ◽  
Vol 51 (Supplement) ◽  
pp. 899
Author(s):  
Whitney A. Welch ◽  
Kara Gavin ◽  
Juned Siddique ◽  
Jason Fanning ◽  
Payton Solk ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Objectively Measured ◽  
Objectively Measured Physical Activity

scholarly journals Effects of a 1-Year Physical Activity Intervention on Markers of Hemostasis among Breast Cancer Survivors: A Randomized Controlled Trial

TH Open ◽  
2021 ◽  
Vol 05 (01) ◽  
pp. e14-e23
Author(s):  
Siv Kjølsrud Bøhn ◽  
Inger Thune ◽  
Vidar Gordon Flote ◽  
Hanne Frydenberg ◽  
Gro Falkenér Bertheussen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Postmenopausal Women ◽  
Cancer Patients ◽  
Physical Activity Intervention ◽  
Intervention Group ◽  
Factor Vii ◽  
Breast Cancer Patients ◽  
Hemostatic Factors

Abstract Introduction Physical activity may reduce the development of breast cancer. Whereas hypercoagulability has been linked to adverse outcomes in breast cancer patients, the effects of physical activity on their hemostatic factors are unknown. The study aimed to assess whether long-term (1 year) physical activity can affect hemostatic factors in breast cancer patients. Methods Fifty-five women (35–75 years) with invasive breast cancer stage I/II were randomized to a physical activity intervention (n = 29) lasting 1 year or to a control group (n = 26), and analyzed as intention to treat. Fibrinogen, factor VII antigen, tissue factor pathway inhibitor, and von Willebrand factor (VWF) antigen as well as prothrombin fragment 1 + 2, the endogenous thrombin potential and D-dimer, were measured in plasma before intervention (baseline), and then after 6 and 12 months. Results Maximal oxygen uptake (measure of cardiorespiratory fitness) decreased the first 6 months among the controls, but remained stable in the intervention group. We found no significant differences between the two study groups regarding any of the hemostatic factors, except a significantly higher increase in factor VII antigen in the intervention group. The effect of the intervention on VWF was, however, significantly affected by menopausal stage, and a significant effect of the intervention was found on VWF among postmenopausal women, even after adjustment for dietary intake. Conclusion Long-term physical activity had no effect on the majority of the hemostatic factors measured, but led to increased plasma concentrations of factor VII antigen and prevented an increase in VWF concentration after breast cancer treatment in postmenopausal women. The clinical impact of these findings for risk of vascular thrombosis warrants further studies.

scholarly journals Changes in physical activity behavior and C-reactive protein in breast cancer patients

2018 ◽  
Vol 52 (7) ◽  
pp. 545-551 ◽  
Author(s):  
Catherine M Sabiston ◽  
Carsten Wrosch ◽  
Andrée L Castonguay ◽  
Benjamin D Sylvester
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Cancer Patients ◽  
Physical Activity Behavior ◽  
Breast Cancer Patients ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Activity Behavior

Influence of physical activity on the immune system in breast cancer patients during chemotherapy

2018 ◽  
Vol 144 (3) ◽  
pp. 579-586 ◽  
Author(s):  
Thorsten Schmidt ◽  
Walter Jonat ◽  
Daniela Wesch ◽  
Hans-Heinrich Oberg ◽  
Sabine Adam-Klages ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Immune System ◽  
Cancer Patients ◽  
Breast Cancer Patients

Impact of physical activity on recurrence dynamics in early breast cancer patients

2020 ◽  
Author(s):  
Elia Mario Biganzoli ◽  
Christine Desmedt ◽  
Romano Demicheli
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Cancer Patients ◽  
Rural Women ◽  
Randomized Clinical Trials ◽  
Urban Women ◽  
Additive Models ◽  
Breast Cancer Patients

Abstract Background Several studies have suggested that pre and/or postdiagnosis physical activity can reduce the risk of recurrence in breast cancer patients, however its effect according to follow-up time has not yet been investigated. Methods We analyzed recurrence and mortality dynamics in randomized clinical trials (RCTs) from Australia and Canada. The combined Australian RCTs evaluated, at median follow-up of 8.3 years, an 8-month pragmatic exercise intervention in 337 women with newly diagnosed breast cancer, while the Canadian RCT evaluated, at median follow-up of 7.4 years, supervised aerobic or resistance exercise during chemotherapy in 242 patients. For each RCT, the control arm consisted of patients undergoing usual care. We estimated the event dynamics by the discrete hazard function, through flexible regression of yearly conditional event probabilities with generalized additive models. Results In the considered RCTs, the recurrence and mortality risk of patients enrolled in the physical activity arm was stably reduced at medium/long term after five year of follow-up. In the Australian RCTs where patients were recruited by urban versus rural area, the latter group did not display benefit from physical activity. Estimated Odds Ratios (95% Confidence Intervals) for Disease Free Survival (DFS) in urban women were 0.63 (0.22-1.85); 0.27 (0.079-0.90); 0.11 (0.013-0.96) at the 3rd, 5th and 7th year of follow-up, respectively. For rural women, DFS patterns were overlapping with ORs approximating 1 at the different years of follow-up. Although not reaching statistical evidence, the estimates in the Canadian trial were in line with the results from the Australian urban women with ORs (95% CI) forDFS of 0.70 (0.33-1.50); 0.47 (0.19-1.18); 0.32 (0.077-1.29) at 3rd, 5th, 7th follow-up year, respectively. Conclusions While we acknowledge that the analyzed RCTs were not designed for investigating disease recurrence over time, these results support the evidence that physical activity reduces the risk of developing medium/long-term metastases. Additional translational research is needed to clarify the mechanisms underlying these observations.

scholarly journals Daily Physical Activity and Symptom Reporting in Breast Cancer Patients Undergoing Chemotherapy: An Intensive Longitudinal Examination

2020 ◽  
Vol 29 (12) ◽  
pp. 2608-2616
Author(s):  
Siobhan M. Phillips ◽  
Whitney A. Welch ◽  
Jason Fanning ◽  
Cesar A. Santa-Maria ◽  
Kara L. Gavin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Cancer Patients ◽  
Daily Physical Activity ◽  
Symptom Reporting ◽  
Breast Cancer Patients ◽  
Longitudinal Examination

Temporal relationships between sleep and physical activity among breast cancer patients with insomnia.

2016 ◽  
Vol 35 (12) ◽  
pp. 1307-1315 ◽  
Author(s):  
Paquito Bernard ◽  
Hans Ivers ◽  
Marie-Hélène Savard ◽  
Josée Savard
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Temporal Relationships

scholarly journals Reduced rates of metabolism and decreased physical activity in breast cancer patients receiving adjuvant chemotherapy

1997 ◽  
Vol 65 (5) ◽  
pp. 1495-1501 ◽  
Author(s):  
W Demark-Wahnefried ◽  
V Hars ◽  
M R Conaway ◽  
K Havlin ◽  
B K Rimer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Adjuvant Chemotherapy ◽  
Cancer Patients ◽  
Breast Cancer Patients

scholarly journals Associations Between Objectively Measured Physical Activity and Quality of Life in Cancer Patients With Brain Metastases

2014 ◽  
Vol 48 (3) ◽  
pp. 322-332 ◽  
Author(s):  
Sonya S. Lowe ◽  
Brita Danielson ◽  
Crystal Beaumont ◽  
Sharon M. Watanabe ◽  
Vickie E. Baracos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Brain Metastases ◽  
Cancer Patients ◽  
Objectively Measured ◽  
Objectively Measured Physical Activity
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