scholarly journals Relationship Between Heart Failure Hospitalization Costs and Left Ventricular Ejection Fraction in an Advanced Aging Society

Author(s):  
Ryota Kaichi ◽  
Kyohei Marume ◽  
Michikazu Nakai ◽  
Masanobu Ishii ◽  
Soshiro Ogata ◽  
...  
Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Kaichi Ryota ◽  
kyohhei marume ◽  
michikazu nakai ◽  
Soshiro Ogata ◽  
Masanobu Ishii ◽  
...  

Introduction: The economic burden associated with heart failure (HF) is expected to increase in the world due to aging. Left ventricular ejection fraction (LVEF) is a basic clinical index that indicates the severity of HF, and guideline-directed medical therapies are recommended stratified by LVEF. However, there is paucity of information between LVEF and hospitalization costs. Hypothesis: Therefore, we evaluated the association between the hospitalization costs and LVEF in elder HF patients in Japan, which is at forefront of aging. Methods: We studied 346 consecutive patients who admitted to Miyazaki prefectural Nobeoka Hospital due to HF between January 2015 and March 2018. Results: Median hospitalization costs were comparable between the HF reduced EF (HFrEF; LVEF<40%: n=129) and HF preserved EF (HFpEF; LVEF≥40%: n=217) ($7128 vs $6580, P =0.373), LVEF was not correlated with hospitalization costs ( P =0.051) (Figure A). Meanwhile, in the subgroup aged over 75 years, median hospitalization costs were significantly higher in HFrEF than in HFpEF ($7249 vs $6471, P =0.031). The HFrEF group also had higher level of brain natriuretic peptide (1011 vs 479 pg/ml, P <0.001), higher prevalence of ischemic heart disease (40% vs 27%, P =0.004), and higher rate of percutaneous coronary intervention (10% vs 2%, P =0.008) than HFpEF group. In addition, LVEF was significantly correlated with hospitalization costs ( P =0.005) (Figure B), and remained as a significant independent predictor of hospitalization costs in multivariate liner regression analysis (β=—0.173, P =0.014). Conclusions: LVEF was not significantly correlated with hospitalization costs in the entire cohort, but was an independent negative factor for hospitalization costs in the subgroup of aged over 75. This might provide helpful evidence for future novel healthcare strategies that target HF inpatient cost reductions.


2011 ◽  
pp. 62-70
Author(s):  
Lien Nhut Nguyen ◽  
Anh Vu Nguyen

Background: The prognostic importance of right ventricular (RV) dysfunction has been suggested in patients with systolic heart failure (due to primary or secondary dilated cardiomyopathy - DCM). Tricuspid annular plane systolic excursion (TAPSE) is a simple, feasible, reality, non-invasive measurement by transthoracic echocardiography for evaluating RV systolic function. Objectives: To evaluate TAPSE in patients with primary or secondary DCM who have left ventricular ejection fraction ≤ 40% and to find the relation between TAPSE and LVEF, LVDd, RVDd, RVDd/LVDd, RA size, severity of TR and PAPs. Materials and Methods: 61 patients (36 males, 59%) mean age 58.6 ± 14.4 years old with clinical signs and symtomps of chronic heart failure which caused by primary or secondary DCM and LVEF ≤ 40% and 30 healthy subject (15 males, 50%) mean age 57.1 ± 16.8 were included in this study. All patients and controls were underwent echocardiographic examination by M-mode, two dimentional, convensional Dopler and TAPSE. Results: TAPSE is significant low in patients compare with the controls (13.93±2.78 mm vs 23.57± 1.60mm, p<0.001). TAPSE is linearly positive correlate with echocardiographic left ventricular ejection fraction (r= 0,43; p<0,001) and linearly negative correlate with RVDd (r= -0.39; p<0.01), RVDd/LVDd (r=-0.33; p<0.01), RA size (r=-0.35; p<0.01), TR (r=-0.26; p<0.05); however, no correlation was found with LVDd and PAPs. Conclusions: 1. Decreased RV systolic function as estimated by TAPSE in patients with systolic heart failure primary and secondary DCM) compare with controls. 2. TAPSE is linearly positive correlate with LVEF (r= 0.43; p<0.001) and linearly negative correlate with RVDd (r= -0.39; p<0.01), RVDd/LVDd (r=-0.33; p<0.01), RA size (r=-0.35; p<0.01), TR (r=-0.26; p<0.05); however, no correlation is found with LVDd and PAPs. 3. TAPSE should be used routinely as a simple, feasible, reality method of estimating RV function in the patients systolic heart failure DCM (primary and secondary).


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