scholarly journals Yu Gan Long Inhibits Liver Fibrosis by Repressing TGF-beta/Smad Signaling and Th17 differentiation

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Xia Yu ◽  
Xiaochuan Ye ◽  
Yanfang Yang ◽  
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RSC Advances ◽  
2018 ◽  
Vol 8 (54) ◽  
pp. 30919-30924
Author(s):  
Jinhang Zhang ◽  
Yanping Li ◽  
Qinhui Liu ◽  
Rui Li ◽  
Shiyun Pu ◽  
...  

NASH is characterized by hepatocellular injury accompanied by steatosis, inflammation and fibrosis. SKLB023 as a potent iNOS inhibitor, suppressed the activation of TGF-β/Smad signaling pathway by blocking iNOS expression to attenuate liver fibrosis in MCD diet-induced mice.


PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e31350 ◽  
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Li-xia Tang ◽  
Rui-hua He ◽  
Guang Yang ◽  
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Vol Volume 11 ◽  
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Hai Zhang ◽  
Yan Cao ◽  
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Haupeltshofer Steffen ◽  
Hasan Maruf ◽  
Neumann Bernhard ◽  
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Gold Ralf ◽  
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2018 ◽  
Vol 841 ◽  
pp. 33-48 ◽  
Author(s):  
Diptadip Dattaroy ◽  
Ratanesh Kumar Seth ◽  
Sutapa Sarkar ◽  
Diana Kimono ◽  
Muayad Albadrani ◽  
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