Metastasizing mixed tumour of the parotid gland presenting as multiple lung metastases

AbstractCarcinoma ex-pleomorphic adenoma is an uncommon tumour of the parotid gland. True malignant mixed tumours of the parotid are rare and we could find only 14 such cases reported. A case of a 76-year-old man diagnosed as suffering from this entity is presented. The diagnosis was based on a series of immunohistochemical studies demonstrating the existence of two separate sarcomatous and carcinomatous elements. The clinical and histological data are presented and the literature is reviewed.

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MIXED TUMOUR OF THE SOFT PALATE RESEMBLING THE MIXED TUMOURS OF THE PAROTID GLAND

The Medical Journal of Australia ◽

10.5694/j.1326-5377.1932.tb90085.x ◽

1932 ◽

Vol 2 (23) ◽

pp. 692-692 ◽

Cited By ~ 1

Author(s):

Douglas G. Carruthers

Keyword(s):

Parotid Gland ◽

Soft Palate ◽

Mixed Tumour ◽

Mixed Tumours

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Giant pleomorphic adenoma of the parotid gland: a case report

South Sudan Medical Journal ◽

10.4314/ssmj.v14i3.8 ◽

2021 ◽

Vol 14 (3) ◽

pp. 101-104

Author(s):

Ernesto Carmona Fernàndez ◽

Jorje Luis Pineda Izquierdo ◽

Osiris Suàrez

Keyword(s):

Parotid Gland ◽

Unusual Case ◽

Malignant Degeneration ◽

Review Of The Literature ◽

Pathologic Examination ◽

Mixed Tumour ◽

Pleomorphic Adenomas ◽

History Of ◽

Mixed Tumours ◽

Left Parotid Gland

Pleomorphic adenomas account for the majority of parotid masses, typically arising in the tail of the gland and enlarging slowly. Most are 2 to 6 cm in size when resected. We report the resection of a benign mixed tumour of the left parotid gland with a history of bleeding. The resected tumour measured 21 cm in diameter, weighed 1.81 kg, and on pathologic examination was a benign mixed tumour without malignant degeneration. The implications of this unusual case for the management of mixed tumours are discussed with a review of the literature.

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Lung Metastases of Epithelial-Myoepithelial Carcinoma of the Parotid Gland Successfully Treated With Chemotherapy: A Case Report

Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.joms.2012.03.031 ◽

2013 ◽

Vol 71 (1) ◽

pp. 220-226 ◽

Cited By ~ 7

Author(s):

Hiroshi Yamazaki ◽

Yoshihide Ota ◽

Takayuki Aoki ◽

Akihiro Kaneko

Keyword(s):

Case Report ◽

Parotid Gland ◽

Lung Metastases ◽

Myoepithelial Carcinoma ◽

Epithelial Myoepithelial Carcinoma

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Ultrastructure of the Parotid Gland of the Nine-Banded Armadillo

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100080626 ◽

1977 ◽

Vol 35 ◽

pp. 640-641

Author(s):

J. R. Ruby

Keyword(s):

Endoplasmic Reticulum ◽

Parotid Gland ◽

Periodic Acid ◽

Acinar Cells ◽

Duct System ◽

Parotid Glands ◽

Dasypus Novemcinctus ◽

Anterior Portion ◽

Periodic Acid Schiff ◽

Thin Sections

Parotid glands were obtained from five adult (four male and one female) armadillos (Dasypus novemcinctus) which were perfusion-fixed. The glands were located in a position similar to that of most mammals. They extended interiorly to the anterior portion of the submandibular gland.In the light microscope, it was noted that the acini were relatively small and stained strongly positive with the periodic acid-Schiff (PAS) and alcian blue techniques, confirming the earlier results of Shackleford (1). Based on these qualities and other structural criteria, these cells have been classified as seromucous (2). The duct system was well developed. There were numerous intercalated ducts and intralobular striated ducts. The striated duct cells contained large amounts of PAS-positive substance.Thin sections revealed that the acinar cells were pyramidal in shape and contained a basally placed, slightly flattened nucleus (Fig. 1). The rough endoplasmic reticulum was also at the base of the cell.

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Ultrastructure of myoepithelial cell in parotid gland

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100103772 ◽

1988 ◽

Vol 46 ◽

pp. 342-343

Author(s):

C. N. Sun

Keyword(s):

Parotid Gland ◽

Osmium Tetroxide ◽

Individual Cell ◽

Branching Processes ◽

Muscle Cells ◽

Myoepithelial Cells ◽

Uranyl Acetate ◽

Thin Sections ◽

Gland Carcinoma ◽

Parotid Gland Carcinoma

Myoepithelial cells have been observed in the prostate, harderian, apocrine, exocrine sweat and mammary glands. Such cells and their numerous branching processes form basket-like structures around the glandular acini. Their shapes are quite different from structures seen either in spindleshaped smooth muscle cells or skeletal muscle cells. These myoepithelial cells lie on the epithelial side of the basement membrane in the glands. This presentation describes the ultrastructure of such myoepithelial cells which have been found also in the parotid gland carcinoma from a 45-year old patient.Specimens were cut into small pieces about 1 mm3 and immediately fixed in 4 percent glutaraldehyde in phosphate buffer for two hours, then post-fixed in 1 percent buffered osmium tetroxide for 1 hour. After dehydration, tissues were embedded in Epon 812. Thin sections were stained with uranyl acetate and lead citrate. Ultrastructurally, the pattern of each individual cell showed wide variations.

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