Giant chondroid syringoma of the eyelid

Chondroid syringoma is a rare mixed tumour of sweat gland origin that is characterised by sweat gland elements in a cartiliginous stroma. Its an uncommon cutaneous tumour of head and neck region with a reported incidence rate of 0.01% to 0.1%. Its occurence in periorbital tissues is rare and usually are small in size. Here we report a case of giant chondroid syringoma (>3 cms) arising in the lower eyelid.

Isolated eyelid chondroid syringoma: a study of two cases

Chondroid syringoma is a benign mixed tumour arising from the sweat glands which can be apocrine (found throughout the surface of the eyelid) or eccrine with a mean age of presentation being 50 years. Here we report two cases of chondroid syringoma of the upper eyelid, one in a young male patient and the other in an elderly woman. Both cases had well-defined lesions involving upper eyelid in the sub-brow region, underwent excisional biopsy, and histopathological findings were consistent with an apocrine type of chondroid syringoma in one case and eccrine type of chondroid syringoma in the second case. It is important to be aware of this entity as a rare cause of eyelid lesion due to the fact that although it is a benign neoplasm, incomplete excision may be associated with recurrence or malignant transformation.

A rare case series of chondroid syringoma in three young patients

Chondroid syringoma is also known as mixed tumour of the skin. It is a rare, biphasic cutaneous neoplasm similar to pleomorphic adenoma of salivary glands. Because of its rarity, many cases are misdiagnosed in the initial stages as cysts or other cutaneous adnexal neoplasms and are often identified only after being sent for histopathological examination.Although it usually presents in middle and older aged patients, we are presenting three younger patients with Chondroid syringoma, located over the back, nose and cheek, respectively.

Giant pleomorphic adenoma of the parotid gland: a case report

Pleomorphic adenomas account for the majority of parotid masses, typically arising in the tail of the gland and enlarging slowly. Most are 2 to 6 cm in size when resected. We report the resection of a benign mixed tumour of the left parotid gland with a history of bleeding. The resected tumour measured 21 cm in diameter, weighed 1.81 kg, and on pathologic examination was a benign mixed tumour without malignant degeneration. The implications of this unusual case for the management of mixed tumours are discussed with a review of the literature.

Chondroid syringoma: an unusual presentation in a 7-year-old boy

Coined in 1961 by Hirsch and Helwig, the term chondroid syringoma refers to a rare mixed tumour of subcutaneous tissue. Histologically, these tumours are almost identical to pleomorphic adenomas, arising from salivary glands. With the obvious difference being the presence of sweat gland tissue (syringoma) within a matrix of cartilage (chondroid). These mixed tumours remain scarce throughout the world, with an incidence of less than 0.098%. The vast majority of cases are reported in middle-aged and older adults, where they typically present as painless swellings in the head and neck, which gradually grow in size.

Unusual Myoid Differentiation in a Canine Benign Mixed Mammary Tumour

This report describes an unusual mesenchymal differentiation in a canine benign mixed mammary tumour. A 13-year-old crossbreed female dog was submitted to surgery to remove an inguinal mammary nodule. The tumour was composed of mammary epithelium and mesenchymal populations, not only of cartilage and bone but also of myoid cells. PTAH demonstrated cross striation of striated muscle, and immunohistochemistry highlighted striated muscle expressing desmin and calponin, and smooth muscle expressing desmin, SMA, and calponin. The tumour was diagnosed as a benign mixed tumour with leio- and rhabdomyoid differentiation. There was no tumour recurrence after one year of clinical follow-up. In conclusion, the well-differentiated features of leiomyocytes and rhabdomyocytes and the growth pattern define the benign origin of the mesenchymal component, which has been confirmed by a benign outcome; therefore, the knowledge of this kind of differentiation is helpful to avoid misdiagnoses.

The Coextensive Circumstance- Parachordoma

Parachordoma is an extremely exceptional, peripherally situated soft tissue neoplasm arising at non axial locations. Also designated as soft tissue “myoepithelioma” or “mixed tumour”, the tumefaction histologically simulates a chordoma of axial skeleton and was referred to as “central chordoma” emerging within non- axial sites. Nevertheless, a distinctive immune profile categorises the lesion as a unique entity.