Non-invasive assessment of renal allograft fibrosis by dynamic sonographic tissue perfusion measurement

2011 ◽  
Vol 52 (8) ◽  
pp. 920-926 ◽  
Author(s):  
Trygve Syversveen ◽  
Knut Brabrand ◽  
Karsten Midtvedt ◽  
Erik H Strøm ◽  
Anders Hartmann ◽  
...  
2018 ◽  
Vol 102 ◽  
pp. S27
Author(s):  
Miriam Banas ◽  
Sindy Neumann ◽  
Philipp Pagel ◽  
Eric Schiffer ◽  
Dominik Chittka ◽  
...  

2008 ◽  
pp. 115-125 ◽  
Author(s):  
Thomas Scholbach ◽  
Jakob Scholbach ◽  
Ercole Di Martino

2019 ◽  
Vol 9 (15) ◽  
pp. 3047 ◽  
Author(s):  
Karthik Vishwanath ◽  
Sara Zanfardino

Diffuse correlation spectroscopy (DCS) has widely been used as a non-invasive optical technique to measure tissue perfusion in vivo. DCS measurements are quantified to yield information about moving scatterers using photon diffusion theory and are therefore obtained at long source-detector separations (SDS). However, short SDS DCS could be used for measuring perfusion in small animal models or endoscopically in clinical studies. Here, we investigate the errors in analytically retrieved flow coefficients from simulated and experimental data acquired at short SDS. Monte Carlo (MC) simulations of photon correlation transport was programmed to simulate DCS measurements and used to (a) examine the accuracy and validity of theoretical analyses, and (b) model experimental measurements made on phantoms at short SDS. Experiments consisted of measurements from a series of optical phantoms containing an embedded flow channel. Both the fluid flow rate and depth of the flow channel from the liquid surface were varied. Inputs to MC simulations required to model experiments were obtained from corrected theoretical analyses. Results show that the widely used theoretical DCS model is robust for quantifying relative changes in flow. We also show that retrieved flow coefficients at short SDS can be scaled to retrieve absolute values via MC simulations.


2009 ◽  
Vol 17 (2) ◽  
pp. 71-85 ◽  
Author(s):  
Thomas Scholbach ◽  
Jakob Scholbach

2003 ◽  
Vol 64 (10) ◽  
pp. S32 ◽  
Author(s):  
Leonard W. Liang ◽  
Qiuheng Zhang ◽  
David Gjertson ◽  
H.Albin Gritsch ◽  
Elaine F. Reed

2012 ◽  
Vol 94 (10S) ◽  
pp. 1186
Author(s):  
D. Rush ◽  
R. Mandal ◽  
D. Wishart ◽  
C. Wiebe ◽  
J. Ho ◽  
...  

2014 ◽  
Vol 58 (1) ◽  
pp. 149-155 ◽  
Author(s):  
Michał Dzięcioł ◽  
Thomas Scholbach ◽  
Ewa Stańczyk ◽  
Justyna Ostrowska ◽  
Wojciech Kinda ◽  
...  

AbstractThe aim of this study was to investigate the usefulness of new software Pixel Flux (PXFX) for clinical evaluation of tissue perfusion in the field of reproduction in dogs. The experiment was performed on six adult Beagle dogs. Different organs and tissues of the animals were examined with the MyLab25 Gold ultrasound system. Blood flow in the ovary, testicle, prostate, the ramification of the penile artery, and the network of blood vessels of the pampiniform plexus were examined with the use of colour coded Doppler technique, and obtained data was evaluated with the PXFX software. The more objective digital evaluation of data obtained with colour Doppler sonography through the application of dynamic tissue perfusion measurements provides new opportunities for diagnosis, as well as continuous monitoring of the function of the examined tissues and organs. The use of PXFX software is strongly indicated as a tool in small animal practice as an additional method for evaluation of tissue perfusion, especially in the cases when other methods like pulsed wave Doppler techniques are difficult to be performed


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