scholarly journals Discovering a new anatomy: exploration of oral mucosa with ultra-high frequency ultrasound

2020 ◽  
Vol 49 (7) ◽  
pp. 20190318 ◽  
Author(s):  
Rossana Izzetti ◽  
Saverio Vitali ◽  
Giacomo Aringhieri ◽  
Teresa Oranges ◽  
Valentina Dini ◽  
...  

Objectives: Ultra-high frequency ultrasound (UHFUS) is a recently developed diagnostic technique involving the use of ultrasound frequencies up to 70 MHz, allowing to obtain 30 µm resolution of targets located within 1 cm from the surface. Oral mucosa can be affected by diverse pathological conditions, which are currently investigated by means of clinical examination. In this scenario, intraoral UHFUS can provide additional information and support clinical assessment of oral mucosa. In this preliminary study, typical features of normal oral mucosa are described, in order to set a benchmark for the future identification of oral soft tissue alterations. Methods: Twenty healthy subjects (10 males and 10 females, mean age 30 years) were enrolled and underwent intraoral UHFUS examination. In all the subjects, tongue, buccal mucosa, gingiva, lip mucosa, and palate were scanned, and images acquired. Intraoral UHFUS scan included Brightness-mode and Doppler mode acquisitions performed with a standardized protocol. UHFUS images were postprocessed and analyzed using a dedicated software. UHFUS-based biomarkers (epithelial thickness, echogenicity, and vascularization) were employed for image description. Results: Normal oral anatomy of the different sites analyzed was described. For all the sites, UHFUS biomarkers were characterized, and information on typical aspect of oral mucosa was retrieved. Conclusions: In this explorative study, we suggest a potential role for intraoral UHFUS in the study of oral mucosa, giving insights into the possibility to improve the assessment, diagnosis, and management of the conditions involving oral mucosa. UHFUS seems a promising tool, which could potentially support clinical examination in daily oral medicine practice.

Author(s):  
Carolina Ávila de Almeida ◽  
Simone Guarçoni ◽  
Bruna Duque Estrada ◽  
Maria Carolina Zafra Páez ◽  
Clarissa Canella

Author(s):  
A. W. Kastelein ◽  
B. C. de Graaf ◽  
Y. P. Latul ◽  
K. W. J. Verhorstert ◽  
J. Holthof ◽  
...  

2020 ◽  
Vol 24 (02) ◽  
pp. 125-134 ◽  
Author(s):  
Domenico Albano ◽  
Giacomo Aringhieri ◽  
Carmelo Messina ◽  
Luca De Flaviis ◽  
Luca Maria Sconfienza

AbstractMusculoskeletal (MSK) ultrasound has well-established advantages, able to investigate very small structures with high resolution and a quick and real-time dynamic evaluation with the possibility of contralateral comparison. Thus ultrasound has kept its own almost exclusive fields of application in daily clinical practice, and it is considered the first-level imaging technique to assess tendons, bursae, and capsuloligamentous structures of small peripheral joints as well as peripheral nerves. Up to now, however, clinical MSK ultrasound imaging could not go beyond the first 1 to 2 cm under the skin, using high-frequency probes up to 18 to 20 MHz with spatial resolution just below millimeters. We present the impressive technical advancements leading to image resolution as low as 30 µm using ultra-high frequency ultrasound (UHFUS) probes up to 70 MHz. High-frequency ultrasound and UHFUS, with frequencies ranging from 22 to 70 MHz, are promising tools to evaluate very superficial structures. In the MSK system, only two articles have assessed its value in limited case series. Future developments may be aimed to better assess ultrastructural changes of very superficial peripheral nerves and other thin structures such as pulleys, retinacula, and tendons.


2022 ◽  
Vol 20 (4) ◽  
pp. 95-100
Author(s):  
M. V. Chubarnova ◽  
A. B. Davydov ◽  
V. A. Esin ◽  
O. B. Davydova ◽  
I. O. Kostin

Introduction. The outbreak of a new coronavirus infection has become a challenge for the global health system. The COVID-19 infection is directly related to various disorders of the cardiovascular system, including the microcirculatory bed, caused by thrombotic events and deteriorations of blood rheology. Aims. The paper reports on the results of a study of Doppler sonographic parameters changes in patients with a novel coronavirus infection over the past 6 months. Materials and methods. We assessed the oral mucosa microcirculation in three segments using the high-frequency ultrasound dopple-rography. Results. We recorded the linear and volumetric blood flow rates and the Gosling and Purselo indexes in the course of our work. When comparing the obtained average statistical parameters of blood flow velocity, the linear and volumetric blood flow rates in patients of both groups were found to be lain in the same range and the mean values of Vas, Vam, Qas were equal. The mean values of the Purselo resistance index were closer to 1,0 in patients with COVID-19, and the values of the Gosling pulsation index (PI) were on average 53.3 % higher than in the control group. Conclusion. We evaluated the screening capabilities and potential of high-frequency ultrasound dopplerography for use in patients of different age groups and different somatic status.


2019 ◽  
Vol 26 (2) ◽  
pp. 200-204 ◽  
Author(s):  
Rossana Izzetti ◽  
Saverio Vitali ◽  
Teresa Oranges ◽  
Valentina Dini ◽  
Marco Romanelli ◽  
...  

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