scholarly journals The ovarian condition diagnosed per rectum andits relations to serum concentrations of progesterone and estradiol-17β and prognosis in cows withcystic ovaries

1976 ◽  
Vol 21 (4) ◽  
pp. 147-153 ◽  
Author(s):  
Toshihiko NAKAO
Keyword(s):  
Serum Concentrations ◽  
Estradiol 17Β

scholarly journals Effects of decreased estradiol-17β on the serum and anterior pituitary IGF-I system in pigs

2005 ◽  
Vol 187 (3) ◽  
pp. 369-378 ◽  
Author(s):  
C K Hilleson-Gayne ◽  
J A Clapper
Keyword(s):  
Anterior Pituitary ◽  
Percentage Increase ◽  
Serum Concentrations ◽  
Blood Samples ◽  
Treatment Groups ◽  
Igf System ◽  
Igf I ◽  
Igf Binding ◽  
Igf Binding Protein ◽  
Estradiol 17Β

To further delineate the role of estradiol in the IGF system an experiment was conducted to determine the dosage of the aromatase inhibitor, anastrozole, needed to decreases serum concentrations of estradiol-17β (E2) in maturing boars. A second experiment was conducted to determine if administration of anastrozole to growing boars decreased serum concentrations of E2 and affected components of the serum and anterior pituitary gland (AP) IGF system vs untreated boars and barrows. In Experiment 1, 12 crossbred boars (292 days, 158 kg) were administered either 0, 1 or 10 mg/day anastrozole (n=4/group) beginning on day 1. Blood samples were collected every 7–14 days. Mean serum concentrations of E2 were decreased (P < 0·05) in the 10 mg group vs the 0 and 1 mg groups by day 36; however, no difference (P > 0·05) existed between the 0 and 1 mg groups. In Experiment 2, 24 crossbred boars and 12 barrows (101 days, 44 kg) were stratified by litter to one of three treatment groups (n=12): boars administered 10 mg/day anastrozole, boars administered 0 mg/day, and barrows administered 0 mg/day. Blood samples were collected and pigs were weighed on day 0 and every 14 days thereafter, then killed on day 84 when blood and APs were collected. The 10 mg/day pigs were fed the anastrozole-amended diet beginning on day 1. Mean serum concentrations of E2 did not differ (P > 0·05) between the 10 mg/day pigs and 0 mg/day pigs on day 0; however, on day 15 through to 84 mean serum concentrations of E2 were greater (P < 0·05) in 0 mg/day pigs than in the 10 mg/day pigs. Mean percentage increase in serum concentrations of IGF-I was greater (P < 0·05) in untreated boars than anastrozole-treated boars and barrows from day 58 through to 84. Mean percentage of basal IGF-I increased (P < 0·05) from day 29 through to 84 in untreated boars. Mean relative amounts of AP IGF-binding protein (IGFBP)-2 and -5 were less (P < 0·01) in 10 mg/day pigs than in the 0 mg/day pigs, but each was greater (P < 0·01) than in barrows administered 0 mg/day. These results indicate anastrozole administered at a dosage of 10 mg/day suppresses serum concentrations of E2 in pigs. Administration of anastrozole to boars reduced the percentage increase in serum concentrations of IGF-I and relative amounts of AP IGFBP-2 and -5. These data further support a role for E2 in regulating components of the IGF system in pigs.

Effect of aglepristone (RU534) administration during follicular phase on progesterone, estradiol‐17β and LH serum concentrations in bitches

2020 ◽  
Vol 55 (12) ◽  
pp. 1794-1802
Author(s):  
Alessandro Troisi ◽  
Angela Polisca ◽  
Lucia Cardinali ◽  
Riccardo Orlandi ◽  
Gabriele Brecchia ◽  
...  
Keyword(s):  
Follicular Phase ◽  
Serum Concentrations ◽  
Estradiol 17Β

Changes in Serum Concentrations of Prolactin, Progestagens, and Estradiol-17β and Biochemical Parameters During Peripartum in an Agalactic Mare

2013 ◽  
Vol 33 (4) ◽  
pp. 279-286 ◽  
Author(s):  
Kenji Korosue ◽  
Harutaka Murase ◽  
Fumio Sato ◽  
Mutsuki Ishimaru ◽  
Gen Watanabe ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Serum Concentrations ◽  
Estradiol 17Β

Immunohistochemical determination of estrogen receptor-α in vaginal and tumor tissues of healthy and TVT-affected bitches and their relation to serum concentrations of estradiol-17β and progesterone

2006 ◽  
Vol 66 (6-7) ◽  
pp. 1587-1592 ◽  
Author(s):  
Claudia Prado de Brito ◽  
Clair Motos de Oliveira ◽  
Fernando Augusto Soares ◽  
Marcelo Faustino ◽  
Cláudio Alvarenga de Oliveira
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Α ◽  
Serum Concentrations ◽  
Tumor Tissues ◽  
Estradiol 17Β

scholarly journals Estradiol-17β Pharmacokinetics and Histological Assessment of the Ovaries and Uterine Horns following Intramuscular Administration of Estradiol Cypionate in Feral Cats

Animals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1708
Author(s):  
Timothy H. Hyndman ◽  
Kelly L. Algar ◽  
Andrew P. Woodward ◽  
Flaminia Coiacetto ◽  
Jordan O. Hampton ◽  
...  
Keyword(s):  
Time Course ◽  
Mixed Effects ◽  
Felis Catus ◽  
Serum Concentrations ◽  
Feral Cats ◽  
Linear Mixed Effects ◽  
Artificial Induction ◽  
Long Acting ◽  
Estrous Behavior ◽  
Estradiol 17Β

The control of feral cats (Felis catus) in Australia is a key biological conservation issue. Male cats are more difficult to control than female cats. Collared and tagged female cats displaying estrous behavior have been considered as a way to lure male cats and reveal their locations. As female cats are seasonal breeders, artificial induction of estrous behavior following the administration of a long-acting estrogen could improve their use for this purpose. Estradiol cypionate was intramuscularly administered to nine entire non-pregnant female feral cats, of unknown estrous status, at 0.1, 0.3, or 0.5 mg/kg. Mean peak serum concentrations of estradiol-17β were 365 pg/mL (0.1 mg/kg), 1281 pg/mL (0.3 mg/kg), and 1447 pg/mL (0.5 mg/kg). The time-course of estradiol-17β concentrations after various doses of estradiol cypionate was assessed using non-compartmental and non-linear mixed-effects methods. At the highest-studied dose (0.5 mg/kg), the 50th percentile of estradiol-17β concentrations exceeded 0.1 ng/mL for 11.8 days, and 0.05 ng/mL for 14.6 days. The duration increased with increasing dose. No signs of toxicity were noticed in any cat during the study. This information will be useful to ongoing studies that are investigating ways to reduce the abundance of feral cats in Australia, especially adult male cats.

Serum levels of estrogens and of five 'steroid sensitive' proteins in early normal pregnancy

1988 ◽  
Vol 118 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Lottie Skjöldebrand Sparre ◽  
Jan Brundin ◽  
Anders Carlström ◽  
Bo von Schoultz ◽  
Kjell Carlström
Keyword(s):  
Serum Levels ◽  
Normal Pregnancy ◽  
The Other ◽  
Sex Hormone Binding Globulin ◽  
Serum Concentrations ◽  
Hormone Binding ◽  
Protein Levels ◽  
Physiological Regulator ◽  
Steroid Sensitive ◽  
Estradiol 17Β

Abstract. Serum concentrations of sex hormone binding globulin (SHBG), pregnancy associated α2-glycoprotein (α2-PAG), caeruloplasmin (Cp), α1-antitrypsin (α1-At) and transferrin (Tf), unconjugated and total estrone, and unconjugated estradiol-17β were measured twice at a 4–5 week interval in 43 cases of early normal pregnancy (gestational weeks 6–19). Significant correlations between estrogen and protein levels in the total material were observed for all proteins except for Tf. However, within 2-week intervals of pregnancy, significant correlations were obtained only in certain intervals between estrogens on one hand and SHBG, Cp and α1-At on the other. Significant correlations between rates of increase of estrogens and of proteins were obtained only at certain occasions for SHBG, Cp, Tf and α1-At. The results indicate that, although estrogens may have a modulatory function in 'steroidsensitive' protein synthesis, they are probably not the main physiological regulator.

ESTROGEN-INDUCED LH RELEASE IN PROGESTERONE-TREATED OVARIECTOMIZED EWES

1974 ◽  
Vol 54 (4) ◽  
pp. 565-572 ◽  
Author(s):  
P. YUTHASASTRAKOSOL ◽  
S. SIMARAKS ◽  
W. M. PALMER ◽  
B. E. HOWLAND
Keyword(s):  
Luteinizing Hormone ◽  
Intramuscular Injection ◽  
Time Course ◽  
Serum Concentrations ◽  
Serum Luteinizing Hormone ◽  
Lh Release ◽  
Estradiol 17Β

Ovariectomized ewes were injected with either 10 or 30 mg of progesterone, administered either intramuscularly (im) or subcutaneously (sc) at 24, 8, 4 h before, or at the same time, as im injections of 1, 2 or 4 mg of estradiol-17β. Determinations of serum luteinizing hormone (LH), estrogen, and progesterone by radioimmunoassay (RIA) were conducted to study the effects of the treatments on LH release, and the time course of estrogen and progesterone serum concentrations following injection. In the first experiment, progesterone failed to block the estrogen-induced LH release in four of six ewes, and in all three ewes of the second experiment. Intramuscular injection of progesterone resulted in higher circulating progesterone concentrations than sc injection and reached peak levels at 2–4 h postinjection. Estrogen reached peak values at 30 min–2 h postinjection. The results showed that progesterone injected at either 4, 8 and 24 h before, or simultaneously with, a pharmacological dosage of estrogen did not consistently block the LH release in ovariectomized ewes.

scholarly journals Effects of Testosterone Administration on Testis and Serum Concentrations of Estradiol-17β in Immature Rats1

1978 ◽  
Vol 19 (5) ◽  
pp. 1070-1075 ◽  
Author(s):  
Alexander J. Szucs ◽  
David T. Armstrong ◽  
David K. Pomerantz
Keyword(s):  
Serum Concentrations ◽  
Testosterone Administration ◽  
Estradiol 17Β

SERUM CONCENTRATIONS OF LH, FSH AND PROLACTIN IN OVARIECTOMIZED EWES FOLLOWING TREATMENT WITH ANDROGENS OR ESTROGENS

1984 ◽  
Vol 64 (1) ◽  
pp. 171-175
Author(s):  
B. E. HOWLAND ◽  
L. M. SANFORD ◽  
W. M. PALMER
Keyword(s):  
Luteinizing Hormone ◽  
Testosterone Propionate ◽  
Single Injection ◽  
Follicle Stimulating Hormone ◽  
Serum Levels ◽  
Estradiol Benzoate ◽  
Serum Concentrations ◽  
Hormone Levels ◽  
Key Words Androgens ◽  
Estradiol 17Β

The effect of a single injection of dihydrotestosterone, testosterone, testosterone propionate, estradiol-17β or estradiol benzoate on serum levels of luteinizing hormone, follicle stimulating hormone and prolactin was studied in ovariectomized ewes. Luteinizing hormone levels increased following treatment with E, EB or TP, prolactin levels increased following treatment with E, EB, T or TP while FSH levels decreased after treatment with either E or EB. Free steroids appeared to produce earlier responses in hormone levels than the corresponding esters. Key words: Androgens, estrogens, gonadotropins, prolactin, ewes.

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