scholarly journals DEOXYRIBONUCLEIC ACID SYNTHESIS IN REGENERATING RAT LIVER STUDIED BY CYTOFLUOROMETRY IN COMBINATION WITH TRITIATED THYMIDINE AUTORADIOGRAPHY

1974 ◽  
Vol 7 (2) ◽  
pp. 105-111 ◽  
Author(s):  
SETSUYA FUJITA ◽  
TSUKASA ASHIHARA ◽  
MASARU FUKUDA ◽  
OSAMU TAKEOKA
Keyword(s):  
Rat Liver ◽  
Deoxyribonucleic Acid ◽  
Tritiated Thymidine ◽  
Acid Synthesis ◽  
Regenerating Rat Liver ◽  
Deoxyribonucleic Acid Synthesis ◽  
Thymidine Autoradiography

scholarly journals Inhibition of polyamine accumulation and deoxyribonucleic acid synthesis in regenerating rat liver

1976 ◽  
Vol 158 (2) ◽  
pp. 485-488 ◽  
Author(s):  
H Pösö ◽  
J Jänne
Keyword(s):  
Partial Hepatectomy ◽  
Ornithine Decarboxylase ◽  
Rat Liver ◽  
Deoxyribonucleic Acid ◽  
Acid Synthesis ◽  
Liver Protein ◽  
Polyamine Synthesis ◽  
Total Liver ◽  
Regenerating Rat Liver ◽  
Deoxyribonucleic Acid Synthesis

Repeated injections of 1,3-diaminopropane into rats after partial hepatectomy caused a repression-type inhibiton of liver ornithine decarboxylase (EC 4.1.1.17) and totally prevented the marked increases in liver putrescine and spermidine concentrations that normally occur in response to partial hepatectomy. The inhibition of polyamine synthesis by diaminopropane was accompanied by a profound decrease (about 80%) in the synthesis of DNA in the regenerating rat liver without any changes in the synthesis of RNA and total liver protein.

scholarly journals Regenerating Rat Liver: Correlations Between Estrogen Receptor Localization and Deoxyribonucleic Acid Synthesis

1984 ◽  
Vol 86 (3) ◽  
pp. 552-557 ◽  
Author(s):  
Antonio Francavilla ◽  
Alfredo Di Leo ◽  
Patricia K. Eagon ◽  
Shi-Quin Wu ◽  
Peter Ove ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Rat Liver ◽  
Deoxyribonucleic Acid ◽  
Acid Synthesis ◽  
Receptor Localization ◽  
Regenerating Rat Liver ◽  
Deoxyribonucleic Acid Synthesis

Duration of Availability of Tritiated Thymidine Following Intraperitoneal Injection

1968 ◽  
Vol 3 (1) ◽  
pp. 89-93
Author(s):  
W. K. BLENKINSOPP
Keyword(s):  
Cell Division ◽  
Intraperitoneal Injection ◽  
Deoxyribonucleic Acid ◽  
Direct Evidence ◽  
Tritiated Thymidine ◽  
Indirect Evidence ◽  
Acid Synthesis ◽  
Single Intraperitoneal Injection ◽  
Deoxyribonucleic Acid Synthesis

Much indirect evidence supports the assumption that tritiated thymidine does not label cells which enter the deoxyribonucleic acid synthesis phase (S) more than 1 h after injection. Direct evidence confirming this assumption was obtained by counting labelled epithelial nuclei in mice killed 1, 4 or 6 h after a single intraperitoneal injection of [3H]thymidine; colchicine was used to prevent the increase in number of labelled nuclei which would otherwise have occurred because of cell division. The proportion of cells labelled was the same at 1 h as at 4 or 6 h after injection of [3H]thymidine. Nuclei were regarded as labelled if they were overlaid by 4 grains or more; comparison of nuclear and background labelling indicated that nuclei overlaid by 3 grains or less represented background labelling.

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