Η σημασία της ισχαιμίας της ωχράς στις φλεβικές αποφράξεις αμφιβληστροειδούς

2018 ◽  
Author(s):  
Κωνσταντίνα Γιαννούλη
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
En Face Oct ◽  
En Face

Να μελετηθεί η στιβάδα των φωτοϋποδοχέων, σε οφθαλμούς με κλαδική απόφραξη φλέβας αμφιβληστροειδούς και ισχαιμία ωχράς, χρησιμοποιώντας μία μέθοδο en face optical coherence tomography (OCT) απεικόνισης της ελλειψοειδούς ζώνης.Μέθοδος: Προσαρμοσμένα OCT scans ωχράς, από 9 ασθενείς (10 οφθαλμοί) με κλαδική απόφραξη φλέβας αμφιβληστροειδούς και ισχαιμία ωχράς , εξήχθησαν και επεξεργάστηκαν (αφαίρεση σκιών προερχόμενων από αγγεία και κυστικούς χώρους, διαχωρισμός στιβάδων και ευθειασμός στο επίπεδο του μελάγχρου επιθηλίου). Η ελλειψοειδής ζώνη διαχωρίστηκε, ευθειάστηκε και χρησιμοποιήθηκε για τη δημιουργία της en face OCT εικόνας. Έγινε σύγκριση μεταξύ των υποανακλαστικών περιοχών απώλειας φωτοϋποδοχέων και των ισχαιμικών περιοχών, όπως οι τελευταίες καταγράφηκαν στις πρώιμες φάσεις της φλουοροαγγειογραφίας.Αποτελέσματα: Οι περιοχές απώλειας του τριχοειδικού δικτύου (στη φλουοραγγειογραφία), παρουσίασαν σαφή συσχέτιση με τις περιοχές διαταραχής της ελλειψοειδούς ζώνης (στην en face OCT απεικόνιση). Οι περιοχές διαταραχής της ελλειψοειδούς ζώνης είχαν ανομοιόμορφη εικόνα, και σαφή ή ασαφή όρια, ανάλογα με τη βαρύτητα της βλάβης.Συμπέρασμα: Η en face OCT απεικόνιση της ελλειψοειδούς ζώνης ανέδειξε μία σαφή συσχέτιση μεταξύ της απώλειας του τριχοειδικού δικτύου και των διαταραχών της ελλειψοειδούς ζώνης σε οφθαλμούς με κλαδική απόφραξη φλέβας αμφιβληστροειδούς. Το εν τω βάθει τριχοειδικό δίκτυο προφανώς συμβάλλει σημαντικά στις μεταβολικές ανάγκες του έξω αμφιβληστροειδούς και, κατά συνέπεια, ισχαιμία στο επίπεδο του εν τω βάθει τριχοειδικού δικτύου έχει σοβαρό αντίκτυπο στην ακεραιότητα των φωτοϋποδοχέων.

scholarly journals Swept-Source Optical Coherence Tomography Detecting Intraoperative Acute Descemet's Fold Formation

2016 ◽  
Vol 7 (2) ◽  
pp. 354-358
Author(s):  
Yu Ichioka ◽  
Akihito Uji ◽  
Nagahisa Yoshimura
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Swept Source ◽  
En Face Oct ◽  
En Face ◽  
Descemet's Membrane ◽  
Descemet’S Membrane ◽  
Oct Imaging ◽  
Fold Formation ◽  
B Scan Images

Background: To present an intraoperative acute Descemet’s fold formation using swept-source optical coherence tomography (SS-OCT) imaging. Case Report: A 67-year-old man complaining of reduced visual acuity in the left eye. A 25-gauge pars plana vitrectomy combined with phacoemulsification cataract surgery was performed to remove the vitreomacular traction. When hydro-sealing was performed, striae rapidly spread in the cornea. SS-OCT B-scan images performed on postoperative day 1 revealed a wavy Descemet’s membrane that might correspond to Descemet’s folds. Pairs of hypo- and hyperreflective narrow lesions running from the wavy Descemet’s membrane to almost half of the thickness of the whole cornea were observed. En face OCT imaging clearly showed the stromal fold, which continuously spread from the Descemet’s fold. Conclusion: The stromal fold might be due to the focal bulge of the stroma posteriorly caused by the rapid volume increase of the stroma which could push Descemet’s membrane posteriorly, thereby forming a wavy Descemet’s membrane layer.

Torpedo Maculopathy Presenting With Fovea Plana in a 21-Year-Old Female

2017 ◽  
Vol 1 (6) ◽  
pp. 424-427 ◽  
Author(s):  
Douglas S. M. Iaboni ◽  
Mark E. Seamone ◽  
Netan Choudhry ◽  
R. Rishi Gupta
Keyword(s):  
Optical Coherence Tomography ◽  
Fluorescein Angiography ◽  
Pigment Epithelium ◽  
Fundus Autofluorescence ◽  
Retinal Pigment ◽  
Spectral Domain ◽  
Optical Coherence ◽  
En Face Oct ◽  
En Face ◽  
Torpedo Maculopathy

Purpose: To report a case of torpedo maculopathy presenting with fovea plana in a 21-year-old female patient. Methods: Multimodal imaging including fluorescein angiography, fundus autofluorescence, and spectral domain optical coherence tomography (OCT) was used to characterize pathology. Results: A well-circumscribed ellipsoidal hypopigmented lesion was observed inferotemporal to the fovea OS. Fluorescein angiography and fundus autofluorescence revealed hyperfluorescence and focal hypoautofluorescence, respectively, corresponding to the hypopigmented lesion. Spectral domain optical coherence tomography imaging of the lesion revealed attenuation of the ellipsoid zone and retinal pigment epithelium with a hyporeflective subretinal cleft. En face OCT imaging demonstrated an area of subretinal hyporeflectivity at the subretinal cleft. Spectral domain optical coherence tomography revealed the absence of a foveal pit. Conclusion: We have described a novel case presentation of fovea plana alongside torpedo maculopathy. The significance of this association remains unclear. Further study into these conditions is necessary to help better determine factors responsible for visual symptoms or lack thereof and circumstances that promote their development.

scholarly journals “En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Flore De bats ◽  
Benjamin Wolff ◽  
Vivien Vasseur ◽  
Aude Affortit ◽  
Laurent Kodjikian ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Domain ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Retinal Layers ◽  
White Dot Syndrome ◽  
En Face Oct ◽  
En Face ◽  
Sd Oct

Purpose. The recent use of “en-face” enhanced-depth imaging spectral-domain optical coherence tomography (EDI SD-OCT) helps distinguish the retinal layers involved in the physiopathology of multiple evanescent white dot syndrome (MEWDS).Methods. Four patients presenting with MEWDS underwent a comprehensive ocular examination including C-scan (“en-face”) EDI SD-OCT at the initial visit and during follow-up.Results. C-scans combined with the other multimodal imaging enabled the visualization of retinal damage. Acute lesions appeared as diffuse and focal disruptions occurring in the ellipsoid and interdigitation zones. The match between autofluorescence imaging, indocyanine green angiography, and “en-face” OCT helped identify the acute microstructural damages in the outer retina further than the choroid. Follow-up using “en-face” EDI-OCT revealed progressive and complete recovery of the central outer retinal layers.Conclusion. “En-face” EDI SD-OCT identified the site of initial damage in MEWDS as the photoreceptors and the interdigitation layers rather than the choroid. Moreover, “en-face” OCT is helpful in the follow-up of these lesions by being able to show the recovery of the outer retinal layers.

Optical Coherence Tomography Angiography of Polypoidal Neovascularization Associated with Choroidal Nevus

2016 ◽  
Vol 27 (1) ◽  
pp. 9-12 ◽  
Author(s):  
Maria Vittoria Cicinelli ◽  
Lorenzo Iuliano ◽  
Alessandro Rabiolo ◽  
Alessandro Marchese ◽  
Giuseppe Querques ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Vascular Endothelial ◽  
Optical Coherence ◽  
Spectral Domain Oct ◽  
En Face Oct ◽  
En Face ◽  
Choroidal Nevus ◽  
Endothelial Growth Factor ◽  
Different Levels

Purpose To report a case of juxtapapillary polypoidal choroidal neovascularization (PCNV) associated with choroidal nevus investigated by means of optical coherence tomography angiography (OCT-A). Methods Case report. Results A 72-year-old woman presented with visual loss and metamorphopsia in her left eye for 5 days secondary to PCNV that developed on the border of a juxtapapillary choroidal nevus. Fluorescein angiography, indocyanine green angiography, and spectral-domain OCT confirmed the diagnosis. En face OCT-A disclosed a large tangled hyperreflective PCNV spreading from the optic disc at different levels of the choriocapillaris; the polyp lumina appeared hyporeflective. The patient was treated with 3 intravitreal injections of anti-vascular endothelial growth factor with partial functional recovery. Conclusions Our case showed the application of OCT-A in the diagnosis of a case of active PCNV complicating a benign intraocular tumor.

scholarly journals Fluorescein Leakage and Optical Coherence Tomography Angiography Features of Microaneurysms in Diabetic Retinopathy

2022 ◽  
Vol 2022 ◽  
pp. 1-9
Author(s):  
Ruoyu Chen ◽  
Anyi Liang ◽  
Jie Yao ◽  
Zicheng Wang ◽  
Yesheng Chen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Fluorescein Angiography ◽  
Detection Rate ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Face Images ◽  
Potential Biomarker ◽  
En Face Oct ◽  
En Face

Background and Objective. To correlate optical coherence tomography angiography (OCTA) characteristics of diabetic microaneurysms (MAs) with leakage status on fluorescein angiography (FA). Patients and Methods. 167 MAs from 39 diabetic eyes were analyzed using OCTA and FA simultaneously. The characteristics of MAs on OCTA en face, OCT en face, and OCT B-scan with flow overlay were evaluated and correlated with fluorescein leakage status. Results. Thirty-six, fifty-two, and seventy-nine MAs showed no, mild, and severe leakage on FA, respectively. Most MAs (61.7%) were centered in the inner nuclear layer. Cystoid spaces were observed adjacent to 60 (35.9%) MAs. MAs with severe leakage had a statistically higher flow proportion compared to MAs with no or mild leakage (both P < 0.001 ). Only 112 MAs (67.1%) were visualized in the OCTA en face images, while 165 MAs (98.8%) could be visualized in the OCT en face images. The location of MAs did not associate significantly with FA leakage status. The presence of nearby cystoid spaces and higher flow proportion by OCT B-scan with flow overlay correlated significantly with FA leakage status. Conclusion. The flow proportion of MAs observed on OCT B-scans with flow overlay might be a potential biomarker to identify leaking MAs. A combination of OCT B-scan, OCT en face, and OCTA en face images increased the detection rate of diabetic MAs in a noninvasive way.

scholarly journals B-Scan and “En-Face” Spectral-Domain Optical Coherence Tomography Imaging for the Diagnosis and Followup of Acute Retinal Pigment Epitheliitis

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Flore De Bats ◽  
Benjamin Wolff ◽  
Martine Mauget-Faÿsse ◽  
Claire Scemama ◽  
Laurent Kodjikian
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Structural Damage ◽  
Outer Nuclear Layer ◽  
Retinal Pigment ◽  
Spectral Domain ◽  
Optical Coherence ◽  
En Face Oct ◽  
En Face ◽  
Sd Oct

Purpose. To report B-scan and “En-face” spectral-domain optical coherence tomography (SD-OCT) findings in acute retinal pigment epitheliitis (ARPE).Methods. Two patients (3 eyes) with ARPE were examined. Fluorescein and indocyanine green (ICGA) angiography, B-scan, and “En-face” SD-OCT were performed in each patient at initial and follow-up visits.Results. Both patients presented with acute onset of blurred vision, and one with bilateral involvement. B-can OCT revealed disruption of the macular retinal pigment epithelial (RPE) inner band layer and photoreceptors’ inner and outer segment (IS-OS) junction. Hyperreflective dots were observed in the outer nuclear layer (ONL) above the RPE/IS-OS disruption. Just around these hyperreflective dots, slight thickening of the hyperreflective IS/OS junction was observed. During the late phase, indocyanine green angiography (ICGA) showed a macular cockade-like hyperfluorescent halo. “En-face” OCT showed the same cockade-like appearance with a hyporeflective center and a hyperreflective border matching the pattern observed on ICGA. At followup, as vision improved without treatment, B-scan OCT demonstrated progressive resolution of the hyperreflective and disrupted lesions; “en-face” OCT also showed disappearance of the macular cockade-like halo with a transient discrete hyperreflective macular star at the RPE level in one eye.Conclusion. “En-face” OCT associated with B-scan SD-OCT analysis appears to be very helpful in the diagnosis and followup of ARPE. The pathophysiology of ARPE remains complex and still poorly understood. These techniques help define the location and extent of structural damage occurring in this disease.

scholarly journals Assessment of Barrett’s esophagus and dysplasia with ultrahigh-speed volumetric en face and cross-sectional optical coherence tomography

Endoscopy ◽  
2018 ◽  
Vol 51 (04) ◽  
pp. 355-359 ◽  
Author(s):  
Osman Ahsen ◽  
Kaicheng Liang ◽  
Hsiang-Chieh Lee ◽  
Michael Giacomelli ◽  
Zhao Wang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Optical Coherence ◽  
Cross Sectional ◽  
En Face Oct ◽  
En Face ◽  
Treatment Naïve ◽  
History Of

Background This study aimed to evaluate the use of ultrahigh-speed volumetric en face and cross-sectional optical coherence tomography (OCT) with micromotor catheters for the in vivo assessment of Barrett’s esophagus and dysplasia. Methods 74 OCT datasets with correlated biopsy/endoscopic mucosal resection histology (49 nondysplastic Barrett’s esophagus [NDBE], 25 neoplasia) were obtained from 14 patients with Barrett’s esophagus and a history of dysplasia and 30 with NDBE. The associations between irregular mucosal patterns on en face OCT, absence of mucosal layering, surface signal > subsurface, and > 5 atypical glands on cross-sectional OCT vs. histology and treatment history were assessed by three blinded readers. Results Atypical glands under irregular mucosal patterns occurred in 75 % of neoplasia (96 % of treatment-naïve neoplasia) vs. 30 % of NDBE datasets (43 % of short- and 18 % of long-segment NDBE). Mucosal layering was absent in 35 % of neoplasia and 50 % of NDBE datasets, and surface signal > subsurface occurred in 29 % of neoplasia and 30 % of NDBE datasets. Conclusions Atypical glands under irregular mucosal patterns are strongly associated with neoplasia, suggesting potential markers for dysplasia and a role in pathogenesis.

scholarly journals En Face Optical Coherence Tomography Imaging of the Choroid in a Case with Central Serous Chorioretinopathy during the Course of Vogt-Koyanagi-Harada Disease: A Case Report

2015 ◽  
Vol 6 (3) ◽  
pp. 488-494 ◽  
Author(s):  
Yuki Komuku ◽  
Chiharu Iwahashi ◽  
Shinsaku Yano ◽  
Chika Tanaka ◽  
Tomoya Nakagawa ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Central Serous Chorioretinopathy ◽  
Serous Retinal Detachment ◽  
Steroid Treatment ◽  
Optical Coherence ◽  
En Face Oct ◽  
En Face ◽  
The Right ◽  
Choroidal Vessels ◽  
Vkh Disease

Vogt-Koyanagi-Harada (VKH) disease and central serous chorioretinopathy (CSC) develop serous retinal detachment; however, the treatment of each disease is totally different. Steroids treat VKH but worsen CSC; therefore, it is important to distinguish these diseases. Here, we report a case with CSC which was diagnosed by en face optical coherence tomography (OCT) imaging during the course of VKH disease. A 50-year-old man was referred with blurring of vision in his right eye. Fundus examination showed bilateral optic disc swelling and macular fluid in the right eye. OCT showed thick choroid, and en face OCT images depicted blurry choroid without clear delineation of choroidal vessels. Combined with angiography findings, this patient was diagnosed with VKH disease and treated with steroids. Promptly, fundus abnormalities resolved with the reduction of the choroidal thickness and the choroidal vessels became visible on the en face images. During the tapering of the steroid, serous macular detachment in the right eye recurred several times. Steroid treatment was effective at first; however, at the fourth appearance of submacular fluid, the patient did not respond. At that time, the choroidal vessels on the en face OCT images were clear, which significantly differed from the images at the time of recurrence of VKH. Angiography also suggested CSC-like leakage. The tapering of the steroids was effective in resolving the fluid. Secondary CSC may develop in the eye with VKH after steroid treatment. En face OCT observation of the choroid may be helpful to distinguish each condition.

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