scholarly journals Changes in Cytokine Profile during Initial Treatment of Pediatric Hemophagocytic Lymphohistiocytosis Associated with Epstein-Barr Virus

2020 ◽  
Vol 87 (3) ◽  
pp. 166-170
Author(s):  
Takahiro Ueda ◽  
Toshikazu Itabashi ◽  
Shingo Yamanishi ◽  
Yujiro Tanabe ◽  
Makoto Migita ◽  
...  
Keyword(s):  
Hemophagocytic Lymphohistiocytosis ◽  
Initial Treatment ◽  
Epstein Barr Virus ◽  
Cytokine Profile ◽  
Barr Virus ◽  
Epstein Barr

Management of Severe Neutropenia With Cyclosporin During Initial Treatment of Epstein-Barr Virus-Related Hemophagocytic Lymphohistiocytosis

2000 ◽  
Vol 36 (3-4) ◽  
pp. 339-346 ◽  
Author(s):  
Shinsaku Imashuku ◽  
Shigeyoshi Hibi ◽  
Kikuko Kuriyama ◽  
Yasuhiro Tabata ◽  
Tetsuo Hashida ◽  
...  
Keyword(s):  
Hemophagocytic Lymphohistiocytosis ◽  
Initial Treatment ◽  
Epstein Barr Virus ◽  
Severe Neutropenia ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Giorgio Berlot ◽  
Ariella Tomasini ◽  
Lorenzo Zandonà ◽  
Eugenio Leonardo ◽  
Rossana Bussani ◽  
...  
Keyword(s):  
Septic Shock ◽  
Infectious Mononucleosis ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Epstein Barr Virus ◽  
Multiple Organ ◽  
Aggressive Lymphoma ◽  
Systemic Involvement ◽  
Barr Virus ◽  
Epstein Barr ◽  
Clinical Pictures

The authors describe the case of a young woman who developed a clinical pictures resembling a septic shock-related multiple organ dysfunction syndrome a couple of months after having been diagnosed suffering from a hemophagocytic lymphohistiocytosis associated with an infectious mononucleosis. Despite the aggressive treatment, which included antibiotics, vasopressors, IV immunoglobulins, and the use of an extracorporeal device aimed to remove mediators released both during sepsis and the cytokine storm determined by the hemophagocytic lymphohistiocytosis, the patient died. At the autopsy, an extremely uncommon aggressive lymphoma of Epstein-Barr virus-positive T-lymphocytes with systemic involvement was discovered.

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