scholarly journals Hydroxyzine revealing acquired neuromuscular weakness in a patient with COVID-19 disease

2021 ◽  
Vol 9 (40) ◽  
pp. 74-76
Author(s):  
Mohamed Bahi ◽  
Younes Aissaoui ◽  
Ayoub Belhadj ◽  
Youssef Qamouss ◽  
Rachid Seddiki
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Side Effects ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Clinical Case ◽  
Distress Syndrome

Acquired neuromuscular weakness often develops in patients with an acute respiratory distress syndrome (ARDS), in particular in patients who are ventilated and sedated for long periods. This has been rarely described in the literature on ARDS secondary to SARS-CoV-2 infection. Our clinical case revealed the existence of these neuromuscular manifestations in the COVID-19 disease after the use of hydroxyzine, an antihistamine whose respiratory side-effects are unknown. Keywords: Neuromuscular weakness, COVID-19, hydroxyzine, hypercapnia.

Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome

2018 ◽  
pp. 123-128
Author(s):  
Duncan McLean ◽  
Matthias Eikermann
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Clinical Case ◽  
Distress Syndrome ◽  
Neuromuscular Blocking ◽  
Neuromuscular Blocking Agents ◽  
Neuromuscular Blockers ◽  
Study Intervention

This chapter provides a summary of the landmark study known as Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome. Do neuromuscular blocking agents (NMBs) improve outcomes in patients with acute respiratory distress syndrome who are receiving mechanical ventilation? Starting with that question, the chapter describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism, and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case. The study found that patients with severe ARDS may benefit from short-term NMB infusions with certain caveats, as noted in the chapter.

scholarly journals Novel technique using surgical scrub sponges to protect the nose and face during prone ventilation for coronavirus disease 2019

2020 ◽  
Vol 134 (8) ◽  
pp. 735-738
Author(s):  
T J Stubington ◽  
M S Mansuri
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Side Effects ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Novel Technique ◽  
Number Of Patients ◽  
Nasal Pressure

AbstractBackgroundCoronavirus disease 2019 is an international pandemic. One of the cardinal features is acute respiratory distress syndrome, and proning has been identified as beneficial for a subset of patients. However, proning is associated with pressure-related side effects, including injury to the nose and face.MethodThis paper describes a pressure-relieving technique using surgical scrub sponges. This technique was derived based on previous methods used in patients following rhinectomy.ConclusionThe increased use of prone ventilation has resulted in a number of referrals to the ENT team with concerns regarding nasal pressure damage. The described technique, which is straightforward and uses readily available materials, has proven effective in relieving pressure in a small number of patients.

scholarly journals Features of imported falciparum malaria: the case report

2021 ◽  
pp. 68-73
Author(s):  
O. Golubovska ◽  
O. Gudzenko ◽  
A. Zaplotna ◽  
I. Shestakova ◽  
O. Bezrodna ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Acute Respiratory Distress Syndrome ◽  
Case Report ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Falciparum Malaria ◽  
Clinical Case ◽  
Distress Syndrome ◽  
Severe Anemia

The clinical case of imported falciparum malaria is described in the article. The diagnosis was confirmed on the 6-th day of the disease when cerebral presentations manifested. The course of the disease was severe and it was characterized by serious complications due to late diagnosis and starting of treatment: malaria coma, malaria alhid, acute respiratory distress syndrome, nozocomial pneumonia, acute renal failure, malaria hepatitis, severe hemolytic anemia. The patient recovered. Presentations of severe anemia progressed after plasmodium disappearance in the blood and persisted after discharge of patient from the hospital.

scholarly journals Early Cytokine Removal in Critical COVID-19 Patients with Extracorporeal Therapies (HA-380 plus High Volume Hemofiltration) May Prevent Progression of Acute Respiratory Distress Syndrome: Case Report

2020 ◽  
pp. 1-3
Author(s):  
Gonzalo Ramírez-Guerrero ◽  
Vicente Torres Cifuentes ◽  
Romyna Baghetti Hernández ◽  
Francisco Villagrán Cortés ◽  
Simón Rojas Doll ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Clinical Case ◽  
Distress Syndrome ◽  
High Volume ◽  
Cytokine Release ◽  
Cytokine Release Syndrome ◽  
Hemodynamic Deterioration ◽  
High Volume Hemofiltration

We present the case of a patient who suffered from acute respiratory distress syndrome caused by pneumonia associated with COVID-19 and cytokine release syndrome. This patient received a high-volume hemofiltration plus adsorption, solving the hemodynamic deterioration, pulmonary infiltrates, and gas exchange. Our clinical case proposes that the extracorporeal therapies can have a role in the management of severe COVID-19.

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