THE EXPERIMENTAL STUDY OF CUPPING THERAPY INTERVENING THE RABBIT MODEL OF COLD STAGNATION LEADING TO BLOOD STASIS SYNDROME BASED ON THE BIOCHEMICAL CRITERION

Objective: Explore the partial mechanisms of cupping therapy by means of the cellular factors in the peripheral blood cells; methods: Replicate the rabbit model of cold stagnation leading to blood stasis by adopting the cold stimulation and randomly dividing 12 rabbits to three groups based on the weight. Observe the sign of the rabbits before and after cupping test, the content of the vascular endothelial growth factor (VEGF), epidermal growth factor (EGF)in the peripheral blood; Results: After replicated the model, the model group and the treatment group gradually appeared the sign of cold stagnation leading to blood stasis. After cupping treatment, the sign of cold stagnation leading to blood stasis of the rabbits gradually disappeared. Compared with the blank controlled group and the model group at the same time, the epidermal growth factor (EGF)in the peripheral blood of the treatment group was much higher after cupping and was statistically difference (p<0.05); Conclusion: The rabbit model of cold stagnation leading to blood stasis could be successfully replicated by the cold irritation; Cupping therapy could produce benign physical stimulation to the local skin through the expression of the cell factors, which might generate continuous weak stimulation, expand and improve the capillaries, thus formed the cascade reaction, and affected the entire microcirculation. Therefore this might be one of the mechanisms of “dredging collaterals”, effect that cupping therapy produced.