The progress of international trade can provide an illustration for the contribution of comparative advantage theory. However, it has had challenges in front of existence and development of intra-trade. Accordingly, comparative advantage as well as dynamic competition theories has become the basic for not only business performance, trade activies and economy but also policy making process. This writing bases on the review of notions and primary regimes of creative destruction, dynamic competition as well as empirical analysis of selected cases for the differences of dynamic competition perspective from the classical attitudes in past. The analysis especially focusses on what the Austrian changed and developed in comparison with the underlying theory of creative destruction. Under case anlysis as well as relevant discussion, the paper points out the dynamic competition advocators’ productive and ambiguous arguments, particularly the economist Gray Becker’s proposal (Nobel Prize in Economics in 1992). Altogher, the research provides some policy implications and initial suggestion for antitrust regulation in Vietnam after making commendations on congesting suggestions for relaxation of antimonopoly regulation.