Radiation-induced cell transformation: transformation efficiencies of different types of ionizing radiation and molecular changes in radiation transformants and tumor cell lines.

OBJECTIVE: The electronic nose is a sensor of volatile molecules that is useful in the analysis of expired gases. Our hypothesis is that the electronic nose can distinguish between different types of upper aerodigestive tract tumor cells in vitro. STUDY DESIGN: Cells from both tumor and normal cell lines were suspended in saline, and a polymer composite electronic nose was used to evaluate the headspace gases. The data were subjected to principal components analysis, and Mahalanobis distances were calculated to demonstrate the ability of the electronic nose to distinguish among samples. RESULTS: The tumor cell lines, including adenocarcinoma, squamous cell carcinoma, and mesothelioma, were distinct from each other, and from the normal fibroblast and smooth muscle cells as seen on canonical discrimination plots. CONCLUSION: The electronic nose can distinguish between tumor cell lines in vitro and has the potential to be a useful screening test for cancer.

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1072 Poster Relationship between DNA-PK activity, intrinsic radiation sensitivity, and radiation-induced chromosome aberrations in human tumor cell lines

Radiotherapy and Oncology ◽

10.1016/s0167-8140(02)83379-5 ◽

2002 ◽

Vol 64 ◽

pp. S312

Keyword(s):

Tumor Cell ◽

Cell Lines ◽

Chromosome Aberrations ◽

Human Tumor ◽

Radiation Sensitivity ◽

Tumor Cell Lines ◽

Human Tumor Cell ◽

Human Tumor Cell Lines ◽

Radiation Induced ◽

Intrinsic Radiation

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Expression of fibroblast growth factors in ultraviolet radiation—induced corneal tumors and corneal tumor cell lines fromMonodelphis domestica

Molecular Carcinogenesis ◽

10.1002/mc.2940070310 ◽

1993 ◽

Vol 7 (3) ◽

pp. 197-205 ◽

Cited By ~ 11

Author(s):

Carol L. K. Sabourin ◽

Donna F. Kusewitt ◽

Lee A. Applegate ◽

Cindy L. Budge ◽

Ronald D. Ley

Keyword(s):

Growth Factors ◽

Ultraviolet Radiation ◽

Tumor Cell ◽

Cell Lines ◽

Fibroblast Growth Factors ◽

Fibroblast Growth ◽

Tumor Cell Lines ◽

Radiation Induced

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Antiproliferative Activity of Cucurbitaceae Species Extracts from Southeast of Mexico

10.20944/preprints201908.0127.v1 ◽

2019 ◽

Author(s):

Karen Morales-Vela ◽

Flor Celeste Pérez-Sánchez ◽

Jose M. Padron ◽

Olivia Márquez-Fernández

Keyword(s):

Tumor Cell ◽

Cell Lines ◽

Antiproliferative Activity ◽

Human Tumor ◽

Tumor Cell Lines ◽

Human Tumor Cell Lines ◽

Organic Extracts ◽

Different Types ◽

A549 Lung

There are many species of endemic plants from Mexico, without food or commercial use, but with different applications in traditional medicine and valuable for their content of secondary metabolites. In this sense, we found two species of Cucurbitacea family plants natives of southeast and gulf of México, with traditionally use how soap and laundry agent, control of some pests, and it has also been used how infusion for the treatment of different types of dermatitis and stomachache. In the present work, we evaluate the antiproliferative activity in vitro, of six crude organic extracts, tested against six human tumor cell lines, A549 (lung), HBL-100 (breast), HeLa (cervix), SW1573 (lung), T-47D (breast) and WiDr (colon), the results indicated that at least three extracts from both species presents an interesting antiproliferative activity on five tumor cell lines.

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