scholarly journals The toxicologic pathology aspects of selected natural herbal products and related compounds

2021 ◽  
Author(s):  
Ruba IBRAHIM ◽  
Abraham NYSKA ◽  
June DUNNICK ◽  
Yuval RAMOT
Keyword(s):  
Herbal Products ◽  
Related Compounds

scholarly journals Liquid Chromatographic Determination of Safrole in Sassafras-Derived Herbal Products

1997 ◽  
Vol 80 (5) ◽  
pp. 1023-1028 ◽  
Author(s):  
Marvin Carlson ◽  
Richard Thompson
Keyword(s):  
Chromatographic Determination ◽  
Reversed Phase ◽  
Herbal Extract ◽  
Root Bark ◽  
Herbal Products ◽  
Relative Standard ◽  
Liquid Chromatographic Determination ◽  
Liquid Chromatographic ◽  
Related Compounds

Abstract A liquid chromatographic (LC) method was developed for determining safrole in herbal products derived from sassafras (Sassafras albidumf as well as related compounds such as isosafrole and dihydrosafrole. The procedure involves solvent extraction and isolation of analyte by reversed-phase LC with UV detection at 235 nm. Safrole is resolved from related compounds and other sample constituents including thymol, a component of thyme. A linear concentration range of 0.003-0.200 mg/mL was obtained for safrole, isosafrole, and dihydrosafrole. Limits of detection (LOD) and quantitation (LOQ) were 0.0015 and 0.0051 μg/mL for safrole, 0.0018 and 0.0061 μg/mL for isosafrole, and 0.0038 and 0.0125 μg/mL for dihydrosafrole, respectively. Intraday relative standard deviations (RSDs) for safrole (n= 5) from various samples ranged from 1.30 to 5.39% at analyte levels of 0.01-1.5%. Safrole contents of 26 samples including root bark powder, leaves, oils, tea concentrate, herbal extract tinctures, and herbal powder capsules ranged from <LOD for most leaf samples to 92.4% for an oil. Recoveries of safrole from fortified samples ranged from 83.6% for an oil to 117.2% for a tincture preparation. Safrole contents of 0.09-4.66 mg/cup were found for brewed teas prepared from sassafras root bark powders and tinctures.

Zebrafish models for hallucinogenic-related compounds

2013 ◽  
Author(s):  
A. V. Kalueff ◽  
A. M. Stewart ◽  
V. Gjeloshi ◽  
D. Kondaveeti ◽  
N. Neelkantan ◽  
...  
Keyword(s):  
Related Compounds

Taxonomic distribution of thymoquinone and related compounds in selected plant species

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
J Táborský ◽  
M Kunt ◽  
P Kloucek ◽  
L Kokoska
Keyword(s):  
Plant Species ◽  
Taxonomic Distribution ◽  
Related Compounds

Effects of herbal products in vitro and in vivo

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
MJ Groot ◽  
MG Pikkemaat ◽  
WD Driessen van Lankveld
Keyword(s):  
Herbal Products
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