scholarly journals THE METHOD OF SPECTRALLY SELECTIVE LASER MUELLER MATRIX POLARIMETRY FOR VERIFICATION OF ACUTE CORONARY INSUFFICIENCY

2016 ◽  
Vol 4 ◽  
pp. 706-710
Author(s):  
Oleh Vanchuliak ◽  
Victor Bachinskiy ◽  
Alexander Ushenko

INTRODUCTION: As the existing methods of evaluation of acute coronary insufficiency currently held is to some extent subjective. However, the specificity of forensic medicine requires objective methods. Thus, there is a necessity for objective methods of diagnosis for acute coronary insufficiency (ACI).OBJECTIVES: The objective of this study isto establish the diagnostic possibilities of the laser method, Muellermatrix polarimetry, on wavelength 450 nm of autofluorescence, with the method of statistical analysis of native heart slices to provide an after-death diagnosis of acute coronary insufficiency.METHODS: In our primary investigation we explored 69 human hearts with ACI, 69 with chronic ischemic heart disease, and 20 from corpses after violent deaths with short agonal period.The samples were studied with a Stokes polarimeter, which was modified to study laser induced autofluorescence.For comparison, histopathological studies were conducted by staining with hematoxylin, basic fuchsine, and picric acid. Data were analyzed statistically.RESULTS: Coordinate and probabilistic distributions of Mueller matrix invariant r14 and r41 laser polarization autofluorescence samples of myocardium were established. A visual determination of ACI, using coordinate distributions or probabilistic distributions, is difficult and hence, we conducted a statistical analysis between pixels of the image. For optically active fluorophores of the myocardium we found a growth (1.5 times) kurtosis of r41 value. Distribution of r41 decreased 1.6 times in the case of ACI.After definition of balanced accuracy, we noted definition of asymmetry and kurtosis of invariant r41with 89 % and 95% accuracy allowed a diagnosis of ACI.CONCLUSION: Using the spectrally selective laser method, Mueller-matrix polarimetry, on wavelength 450 nm of autofluorescence with method of statistical analysis of native heart slices allows for diagnosis of ACI with high accuracy.

1949 ◽  
Vol 15 (1) ◽  
pp. 72-82 ◽  
Author(s):  
SIMON DACK ◽  
JACOB STONE ◽  
DAVID H. PALEY ◽  
ARTHUR M. MASTER

Heart ◽  
1977 ◽  
Vol 39 (4) ◽  
pp. 363-370 ◽  
Author(s):  
L J Day ◽  
G E Thibault ◽  
E Sowton

2019 ◽  
Vol 18 (1) ◽  
pp. 1-35 ◽  
Author(s):  
Cecilia I. Nievas ◽  
Julian J. Bommer ◽  
Helen Crowley ◽  
Jan van Elk

Abstract Despite their much smaller individual contribution to the global counts of casualties and damage than their larger counterparts, earthquakes with moment magnitudes Mw in the range 4.0–5.5 may dominate seismic hazard and risk in areas of low overall seismicity, a statement that is particularly true for regions where anthropogenically-induced earthquakes are predominant. With the risk posed by these earthquakes causing increasing alarm in certain areas of the globe, it is of interest to determine what proportion of earthquakes in this magnitude range that occur sufficiently close to population or the built environment do actually result in damage and/or casualties. For this purpose, a global catalogue of potentially damaging events—that is, earthquakes deemed as potentially capable of causing damage or casualties based on a series of pre-defined criteria—has been generated and contrasted against a database of reportedly damaging small-to-medium earthquakes compiled in parallel to this work. This paper discusses the criteria and methodology followed to define such a set of potentially damaging events, from the issues inherent to earthquake catalogue compilation to the definition of criteria to establish how much potential exposure is sufficient to consider each earthquake a threat. The resulting statistics show that, on average, around 2% of all potentially-damaging shocks were actually reported as damaging, though the proportion varies significantly in time as a consequence of the impact of accessibility to data on damage and seismicity in general. Inspection of the years believed to be more complete suggests that a value of around 4–5% might be a more realistic figure.


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