scholarly journals Quality of life of patients with hard-to-heal leg ulcers: a review of nursing documentation

2020 ◽  
Vol 25 (Sup12) ◽  
pp. S13-S19
Author(s):  
Malin Olsson ◽  
Anne Friman
Keyword(s):  
Quality Of Life ◽  
Wound Healing ◽  
Depressed Mood ◽  
Health Professionals ◽  
Healing Process ◽  
Social Aspects ◽  
Wound Healing Process ◽  
Leg Ulcers ◽  
Nursing Documentation

People with hard-to-heal leg ulcers experience reduced quality of life (QoL), including physical, mental and social aspects; this, in turn, negatively affects the wound healing process. QoL is often overlooked by health professionals treating those with hard-to-heal wounds, for whom the focus is instead on the wound itself and the healing process. This study aimed to investigate how the QoL of patients with hard-to-heal wounds is documented and followed up by nurses. The healthcare records of patients with hard-to-heal wounds were reviewed using an audit instrument. Data were collected retrospectively from 12 patient healthcare records. The nursing documentation included few notes related to patients' QoL. The nurses focused on issues such as nutrition, mobilisation and smoking, while the patients expressed concerns about anxiety/depressed mood, pain and sleeping difficulties. Only nine of the documented problems were approved according to the instrument. Most importantly, documentation of planned interventions and outcomes was missing. Documentation by nurses around the QoL of patients with hard-to-heal wounds is lacking, because of which QoL might be neglected and wound healing might not progress well.

scholarly journals The effect of earthworm extract on promoting skin wound healing

2018 ◽  
Vol 38 (2) ◽  
Author(s):  
Zhen-han Deng ◽  
Jian-jian Yin ◽  
Wei Luo ◽  
Ronak Naveenchandra Kotian ◽  
Shan-shan Gao ◽  
...  
Keyword(s):  
Wound Healing ◽  
Healthcare System ◽  
Transforming Growth Factor ◽  
Healing Process ◽  
White Blood Cells ◽  
Skin Wound ◽  
Wound Healing Process ◽  
Blood Capillary ◽  
Skin Wound Healing

Chronic nonhealing wounds pose a significant challenge to healthcare system because of its tremendous utilization of resources and time to heal. It has a well-deserved reputation for reducing the quality of life for those affected and represent a substantial economic burden to the healthcare system overall. Earthworms are used as a traditional Chinese medicine, and have been applied pharmacologically and clinically since a long time in China. However, there is paucity in data regarding its wound healing effects. Therefore, we investigated the effect of earthworm extract (EE) on skin wound healing process. The obtained data showed that EE has healing effects on local wound of mice. It decreased the wound healing time and reduced the ill-effects of inflammation as determined by macroscopic, histopathologic, hematologic, and immunohistochemistry parameters. The potential mechanism could be accelerated hydroxyproline and transforming growth factor-β secretion—thus increasing the synthesis of collagen, promoting blood capillary, and fibroblast proliferation. It could accelerate the removal of necrotic tissue and foreign bodies by speeding up the generation of interleukin-6, white blood cells, and platelets. It thus enhances immunity, reduces the risk of infection, and promotes wound healing. All in all, the obtained data demonstrated that EE improves quality of healing and could be used as a propitious wound healing agent.

Effect of Physical Therapy on Wound Healing and Quality of Life in Patients With Venous Leg Ulcers

2015 ◽  
Vol 151 (3) ◽  
pp. 320 ◽  
Author(s):  
Elizabeth Yim ◽  
Robert S. Kirsner ◽  
Robert S. Gailey ◽  
David W. Mandel ◽  
Suephy C. Chen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Wound Healing ◽  
Physical Therapy ◽  
Leg Ulcers ◽  
Venous Leg Ulcers

scholarly journals Distinct Wound Healing and Quality-of-Life Outcomes in Subgroups of Patients With Venous Leg Ulcers With Different Symptom Cluster Experiences

2017 ◽  
Vol 53 (5) ◽  
pp. 871-879 ◽  
Author(s):  
Kathleen Finlayson ◽  
Christine Miaskowski ◽  
Kimberly Alexander ◽  
Wei-Hong Liu ◽  
Bradley Aouizerat ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Wound Healing ◽  
Symptom Cluster ◽  
Leg Ulcers ◽  
Life Outcomes ◽  
Venous Leg Ulcers ◽  
Quality Of Life Outcomes

scholarly journals What Is the Impact of Depletion of Immunoregulatory Genes on Wound Healing? A Systematic Review of Preclinical Evidence

2020 ◽  
Vol 2020 ◽  
pp. 1-19
Author(s):  
Bárbara Cristina Félix Nogueira ◽  
Artur Kanadani Campos ◽  
Raul Santos Alves ◽  
Mariáurea Matias Sarandy ◽  
Rômulo Dias Novaes ◽  
...  
Keyword(s):  
Wound Healing ◽  
Methodological Quality ◽  
Healing Process ◽  
Heterogeneous Data ◽  
Skin Wound ◽  
Wound Healing Process ◽  
Extracellular Molecules ◽  
Knockout Animals ◽  
The Impact

Cytokines and growth factors are known to play an important role in the skin wound closure process; however, in knockout organisms, the levels of these molecules can undergo changes that result in the delay or acceleration of this process. Therefore, we systematically reviewed evidence from preclinical studies about the main immunoregulatory molecules involved in skin repair through the analysis of the main mechanisms involved in the depletion of immunoregulatory genes, and we carried out a critical analysis of the methodological quality of these studies. We searched biomedical databases, and only original studies were analyzed according to the PRISMA guidelines. The included studies were limited to those which used knockout animals and excision or incision wound models without intervention. A total of 27 studies were selected; data for animal models, gene depletion, wound characteristics, and immunoregulatory molecules were evaluated and compared whenever possible. Methodological quality assessments were examined using the ARRIVE and SYRCLE’s bias of risk tool. In our review, the extracellular molecules act more negatively in the wound healing process when silenced and the metabolic pathway most affected involved in these processes was TGF-β/Smad, and emphasis was given to the importance of the participation of macrophages in TGF-β signaling. Besides that, proinflammatory molecules were more evaluated than anti-inflammatory ones, and the main molecules evaluated were, respectively, TGF-β1, followed by VEGF, IL-6, TNF-α, and IL-1β. Overall, most gene depletions delayed wound healing, negatively influenced the concentrations of proinflammatory cytokines, and consequently promoted a decrease of inflammatory cell infiltration, angiogenesis, and collagen deposition, compromising the formation of granulation tissue. The studies presented heterogeneous data and exhibited methodological limitations; therefore, mechanistic and highly controlled studies are required to improve the quality of the evidence.

scholarly journals Influence of placebo effects on quality of life and wound healing in patients with chronic venous leg ulcers

2019 ◽  
Vol 18 (2) ◽  
pp. 103-109 ◽  
Author(s):  
Finja Jockenhöfer ◽  
Christopher Knust ◽  
Sven Benson ◽  
Manfred Schedlowski ◽  
Joachim Dissemond
Keyword(s):  
Quality Of Life ◽  
Wound Healing ◽  
Leg Ulcers ◽  
Placebo Effects ◽  
Venous Leg Ulcers

Validation of Harikrishna Periwound Skin Classification for wound assessment

2020 ◽  
Vol 29 (Sup4) ◽  
pp. S44-S48
Author(s):  
Harikrishna K. R. Nair ◽  
Sylvia SY Chong ◽  
Abdul Manan Othman
Keyword(s):  
Quality Of Life ◽  
Wound Healing ◽  
Health Professionals ◽  
Real Life ◽  
Staff Nurses ◽  
Wound Management ◽  
Medical Assistants ◽  
Wound Assessment

Objective: To validate the accuracy and reliability of Harikrishna Periwound Skin Classification (HPSC) for wound assessment. Method: Post-basic students (staff nurses and medical assistants) were given real life pictures showing the wound and periwound area. The students were asked to classify all pictures according to the HPSC at zero months (before attachment) and after two months of attachment. The images were the same but the answers were never given or discussed after the first test. Results: A total of 30 post-basic students participated in the study, assessing wound 30 images. The results showed that there was an increase of 25.42% in accuracy of wound assessment using the HSPC after two months of clinical attachment compared to pre-attachment. The reliability of the HPSC in wound assessment 79.87%. Conclusion: Health professionals have to be able to assess and classify wounds accurately to be able to manage them accordingly. Assessment and classifications of the periwound skin are important and need to be validated and integrated as a part of a full wound assessment. With experience and adequate training, health professionals are able to comprehensively assess wounds using the validated tool, to enable effective wound management and treatment, accelerating wound healing and improving the quality of life for patients.

scholarly journals Wound dressings: curbing inflammation in chronic wound healing

2021 ◽  
Author(s):  
Davide Vincenzo Verdolino ◽  
Helen A. Thomason ◽  
Andrea Fotticchia ◽  
Sarah Cartmell
Keyword(s):  
Wound Healing ◽  
Chronic Wounds ◽  
Chronic Wound ◽  
Wound Care ◽  
Healing Process ◽  
Standard Of Care ◽  
The Elderly ◽  
Wound Dressings ◽  
Wound Healing Process

Chronic wounds represent an economic burden to healthcare systems worldwide and a societal burden to patients, deeply impacting their quality of life. The incidence of recalcitrant wounds has been steadily increasing since the population more susceptible, the elderly and diabetic, are rapidly growing. Chronic wounds are characterised by a delayed wound healing process that takes longer to heal under standard of care than acute (i.e. healthy) wounds. Two of the most common problems associated with chronic wounds are inflammation and infection, with the latter usually exacerbating the former. With this in mind, researchers and wound care companies have developed and marketed a wide variety of wound dressings presenting different compositions but all aimed at promoting healing. This makes it harder for physicians to choose the correct therapy, especially given a lack of public quantitative data to support the manufacturers’ claims. This review aims at giving a brief introduction to the clinical need for chronic wound dressings, focusing on inflammation and evaluating how bio-derived and synthetic dressings may control excess inflammation and promote healing.

Changes of wound dimensions and pain assessment in response to hyperbaric oxygenation therapy

2018 ◽  
Vol 86 (4) ◽  
pp. 259
Author(s):  
Emilia Mikołajewska ◽  
Sławomir Wawrzyniak ◽  
Piotr Dzięgielewski ◽  
Aleksander Goch
Keyword(s):  
Wound Healing ◽  
Pain Assessment ◽  
Hyperbaric Oxygenation ◽  
Chronic Wounds ◽  
Healing Process ◽  
Adult Patients ◽  
Wound Healing Process ◽  
Before And After ◽  
Wound Length

Introduction. Novel approaches to wound healing can provide decreased risk of complications, wider possibilities of further treatment, rehabilitation and care, and improved patient’s quality of life. Most recent studies support the concept that HBOT accelerates the wound healing process. Aim. This paper aims at presentation and discussion the outcomes of a research on chronic wounds healing using the HBOT. Particular attention was paid to changes of wound dimensions and pain assessment in response to HBOT.Material and Methods. Inclusion criteria meet the medical records of eighty‑nine adult patients with chronic wounds aged 18–85 years treated with HBOT. Wound length, wound width and pain were measured twice: before and after treatment.Results. There have been observed favourable and statistically significant changes in all measured areas: pain assessment, wound length, and wound width. Improvement of pain assessment occured in 94.38% of patients, improvement of maximal wound length occurred in 94.38% of patients, improvement of maximal wound width occurred in 86.52% of patients.Conclusions. Application HBOT in adult patients with chronic wound is an effective method of treatment. Age above 62 years, sex (men), lack of obesity, and number of HBOT sessions higher than 29 can be regarded as useful prognostic signs, however there is need for further research.

scholarly journals Platlet-Rich Plasma – Review of Literature

PRILOZI ◽  
2021 ◽  
Vol 42 (1) ◽  
pp. 127-139
Author(s):  
Bisera Nikolovska ◽  
Daniela Miladinova ◽  
Sofija Pejkova ◽  
Andrijana Trajkova ◽  
Gordana Georgieva ◽  
...  
Keyword(s):  
Wound Healing ◽  
Platelet Rich Plasma ◽  
Healing Process ◽  
Coagulation Factors ◽  
Wound Healing Process ◽  
Adhesive Properties ◽  
Autologous Whole Blood ◽  
Complete Set ◽  
Normal Architecture

Abstract Wound healing is a dynamic and physiological process for restoring the normal architecture and functionality of damaged tissue. Platelet-rich plasma (PRP) is an autologous whole blood product that contains a large number of platelets in a small volume of plasma with complete set of coagulation factors, which are in physiological concentrations. PRP has haemostatic, adhesive properties and acts supraphysiologically in the process of wound healing and osteogenesis. Platelets play a very important role in the wound healing process by providing growth factors that enhance the rate and quality of wound healing by many different mechanisms. The aim of this review is to describe: the biology of platelets and their role in the wound healing process, the terminology of platelet rich products, PRP preparation, activation and concentration of PRP, as well as the use of PRP in plastic surgery.

scholarly journals POSSIBILITY OF NEW LYMPHATIC PATHWAY CREATION THROUGH NEO-LYMPHANGIOGENESIS INDUCED BY SUBDERMAL DISSECTION

Lymphology ◽  
2022 ◽  
Vol 54 (3) ◽  
Author(s):  
T. Yamamoto ◽  
N. Yamamoto
Keyword(s):  
Quality Of Life ◽  
Medical Records ◽  
Surgical Intervention ◽  
Healing Process ◽  
Wound Healing Process ◽  
Life Score ◽  
Significant Difference ◽  
Lymphatic Pathway ◽  
Lymphatic Pathways

Surgical intervention and subsequent wound healing process are known to induce neo-lymphangiogenesis, but few studies have been reported to utilize this mechanism for lymphedema treatment. The aim of this study was to evaluate feasibility of subdermal dissection for neo-lymphangiogenesis induction (SDN) to treat lower extremity lymphedema (LEL). Medical records of secondary LEL patients who had undergone ICG lymphography and SDN procedure were reviewed. SDN was performed by dissecting fat tissues just below the dermis from the most proximal area showing dermal backflow through abdominal-toaxillary lymphatic pathways. Perioperative lymphedematous conditions were evaluated with lymphedema quality of life score (LeQOLiS) and LEL index. Seventeen female patients were included. SDN could be performed in 10 minutes on average without postoperative complication. Postoperative ICG lymphography showed new lymphatic pathways in 6 (35.3%) cases. Postoperative LeQOLiS ranged from 9 to 66, which was statistically lower than preoperative LeQOLiS (32.9 ± 19.2 vs. 36.6 ± 19.3, p = 0.048), whereas there was no statistically significant difference between pre- and post-operative LEL index (275.2 ± 23.3 vs. 270.5 ± 20.8, P = 0.073). Subdermal dissection, although its probability is not high, has a potential to induce neo-lymphangiogenesis. Further studies are required to improve and demonstrate efficacy of the procedure for new lymphatic pathway creation.

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