Lung transplantation for silicosis and recovery: an Australian case study

2021 ◽  
Vol 30 (3) ◽  
pp. 178-183
Author(s):  
Kate McEwen ◽  
Lyndell Brodie
Keyword(s):  
Lung Transplantation ◽  
Medication Management ◽  
Social Situation ◽  
Bilateral Lung Transplantation ◽  
Transplantation Surgery ◽  
Australian Case ◽  
Bilateral Lung ◽  
End Stage

Lung transplantation is a well-established treatment for a variety of end-stage pulmonary diseases. However, the journey of a lung transplant recipient is complex and multifaceted. Silicosis is a rare indication for lung transplantation, but no other treatment is yet available for this disease in its end stages. This Australian case study presents a 52-year-old man with silicosis who received bilateral lung transplantation. The patient was frequently noncompliant with noninvasive ventilation therapy and experienced the complication of type 2 respiratory failure. Patient education and support provided, particularly around medication management following transplantation surgery, are discussed here. The patient's social situation and its implications for both him and his family are also considered.

Lung transplantation for silicosis: a case study

2019 ◽  
Vol 28 (Volume 28 Issue 2) ◽  
pp. 13-17
Author(s):  
Kate McEwen ◽  
Lyndell Brodie
Keyword(s):  
Lung Transplantation ◽  
Medication Management ◽  
Social Situation ◽  
Non Invasive ◽  
Transplantation Surgery ◽  
Non Invasive Ventilation ◽  
The Social ◽  
End Stage

Lung transplantation has become a well-established treatment for a variety of end-stage pulmonary diseases. Silicosis is a rare indication for lung transplantation; however, there is currently no other treatment available for the disease in its end stages. This case study presents a 52-year-old man who presented with silicosis for lung transplantation. His in-hospital recovery journey is examined and discussion is provided about his experience of complications, including type 2 respiratory failure and non-compliance with non-invasive ventilation therapy. The patient education and support provided, particularly related to medication management following transplantation surgery, if of key importance during the transplant recipient’s recovery. The social situation and its implications for both the patient and their family should also be considered. Both these aspects are also explored in the context of the case presented.

Bilateral Lung Transplantation for Castleman Disease with End‐stage Bronchiolitis Obliterans

2021 ◽  
Author(s):  
Bingqing Yue ◽  
Jian Huang ◽  
Lei Jing ◽  
Huaqing Yu ◽  
Dong Wei ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Bronchiolitis Obliterans ◽  
Castleman Disease ◽  
Bilateral Lung Transplantation ◽  
Bilateral Lung ◽  
End Stage

scholarly journals Transmission of glioblastoma multiforme following bilateral lung transplantation from an affected donor: Case study and review of the literature

2004 ◽  
Vol 6 (3) ◽  
pp. 259-263 ◽  
Author(s):  
Mary Y. Armanios ◽  
Stuart A. Grossman ◽  
Stephen C. Yang ◽  
Barbara White ◽  
Arie Perry ◽  
...  
Keyword(s):  
Glioblastoma Multiforme ◽  
Lung Transplantation ◽  
Review Of The Literature ◽  
Bilateral Lung Transplantation ◽  
Bilateral Lung

scholarly journals Bilateral Lung Transplantation for End-Stage Respiratory Failure from COVID-19 Pneumonia

2021 ◽  
Vol 40 (4) ◽  
pp. S500
Author(s):  
N. Maniar ◽  
J. Coster ◽  
G. Li ◽  
J. Segraves ◽  
M. Hemmersbach-Miller ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Lung Transplantation ◽  
Bilateral Lung Transplantation ◽  
Bilateral Lung ◽  
End Stage

scholarly journals Relapse of Lymphangioleiomyomatosis Five Years after Bilateral-Lung Transplantation

2021 ◽  
Vol 24 (9) ◽  
pp. 701-703
Author(s):  
Jalal Heshmatnia ◽  
Maryam Sadat Mirenayat ◽  
Mitrasadat Rezaei ◽  
Felix Bongomin ◽  
Mehrdad Bakhshayeshkaram ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Viable Option ◽  
Bilateral Lung Transplantation ◽  
Pulmonary Lymphangioleiomyomatosis ◽  
Progressive Dyspnea ◽  
Stage Disease ◽  
Uncommon Disease ◽  
Progressive Respiratory Failure ◽  
Bilateral Lung ◽  
End Stage

Pulmonary lymphangioleiomyomatosis (LAM) is an uncommon disease principally affecting women during childbearing years and eventually leading to progressive respiratory failure. Lung transplantation is a viable option for patients with end-stage disease. LAM-related complications remain common, but recurrence of LAM following allograft transplantation is rare. We present a 25-year-old woman who presented with progressive dyspnea five years after bilateral lung transplantation for end-stage LAM. Histological examination of transbronchial lung biopsy sample confirmed recurrent LAM. We changed cyclosporine to sirolimus and she is currently being considered for re-transplantation.

Long-Term Results of Bilateral Lung Transplantation in Patients With End-Stage Pulmonary Lymphangioleiomyomatosis

2019 ◽  
Vol 29 (2) ◽  
pp. 115-121 ◽  
Author(s):  
Jawad Salman ◽  
Fabio Ius ◽  
Wiebke Sommer ◽  
Thierry Siemeni ◽  
Felix Fleissner ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Transplantation ◽  
Short Form ◽  
Self Report ◽  
Long Term Results ◽  
Actuarial Survival ◽  
Bilateral Lung Transplantation ◽  
Bilateral Lung ◽  
End Stage

Introduction: Lymphangioleiomyomatosis (LAM) is a rare disease in women, leading to progressive deterioration of lung function and respiratory failure. We describe the outcome of patients with end-stage LAM who underwent lung transplantation at our center. Materials and Methods: The records of patients with LAM transplanted at our institution between February 1997 and May 2015 were reviewed retrospectively. Morbidity and mortality were analyzed, and actuarial survival was calculated using Kaplan-Meier methods. The cumulative survival of transplant patients with LAM at our center was compared with survival after transplantation due to different diseases at our center and the results of the International Society for Heart and Lung Transplantation. Quality of life was assessed by a patient self-report at the end of the first postoperative year. Results: During the study period, 25 patients underwent lung transplantation for LAM. All patients were women with a mean age of 50 (9) years. Thirteen patients (52%) had undergone previous thoracotomy. All patients (100%) received bilateral lung transplantation. One (4%) case of in-hospital mortality occurred and 9 (36%) late deaths. Two (8%) cases of late death were due to chronic lung allograft dysfunction. The 1-, 3-, and 5-year survival rates were 92%, 84%, and 76%, respectively. Quality-of-life ratings were above the normal in all eight 36-Item Short Form Health Survey subscales 1 year after transplantation. Conclusions: Lung transplantation offers a valuable therapy for patients with end-stage pulmonary LAM.

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