The prosthodontic rehabilitation of edentulous spaces is a very common demand of patients. However, in the majority of cases, this is not as simple as it sounds. Because in time, the consequences of tooth extraction affect the neighboring teeth, leading to tooth migrations, tooth rotations, tilting, and the sagittal and vertical reduction of the edentulous spaces that have to be restored. Using segmental orthodontics on a limited number of teeth associated with skeletal anchorage, we can significantly improve the clinical situation, correcting these consequences of tooth migration following extraction, allowing the prosthodontist to have a better starting point in the process of rehabilitation. The treatment time is shorter than compared to a comprehensive orthodontic treatment, and thus, the patient acceptance may be increased. Once the spaces are correctly calibrated, and the tooth migrations have been corrected, the prosthodontist can restore the missing teeth as minimally invasive as possible.