Scanning electron microscopy of composite hydroxylapatite/plaster implants for bone reconstruction

Author(s):  
J. S. Hanker ◽  
B. L. Giammara

Nonresorbable sintered ceramic hydroxylapatite (HA) is widely employed for filling defects in jaw bone. The small particles used for alveolar ridge augmentation in edentulous patients or for infrabony defects due to periodontal disease tend to scatter when implanted using water or saline as the vehicle. Larger blocks of this material used for filling sockets after tooth extraction don't fit well. Studies in our laboratory where we compared bovine serum albumin, collagen and plaster of Paris as binders to prevent particle scatter during implantation suggested that plaster was most useful for this purpose. In addition to preventing scatter of the particles, plaster enables the formation of implants of any size and.shape either prior to or during surgery. Studies with the PATS reaction have indicated that plaster acts as a scaffold for the incorporation of HA particles into bone in areas where the implant contacts either host bone or periosteum. The shape and integrity of the implant is maintained by the plaster component until it is replaced over a period of days by fibrovascular tissue.

Author(s):  
J. S. Hanker ◽  
D. A. Randolph ◽  
B. L. Giammara ◽  
P. E. Yates ◽  
R. G. Lange

Nonresorbable sintered hydroxylapatite (HA) particles are widely used for alveolar ridge augmentation in edentulous patients to support dentures or for filling infrabony defects due to bone resorption in progressive periodontal disease. these particles tend to scatter when implanted with water or saline as the vehicle. studies in our laboratory of different binders to prevent particle scatter during implantation suggested the utility of plaster of paris for this purpose. In most operative procedures the ha/plaster mixtures moistened with water or saline set and harden adequately, especially when a small amount of potassium sulfate has been added to the plaster component to accelerate setting. when the implantation site is bloody or has an excess of tissue fluids, setting of the mixture is considerably slowed if, indeed, the plaster is not actually washed away.


2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Gaia Pellegrini ◽  
Giorgio Pagni ◽  
Giulio Rasperini

Guided tissue regenerative (GTR) therapies are performed to regenerate the previously lost tooth supporting structure, thus maintaining the aesthetics and masticatory function of the available dentition. Alveolar ridge augmentation procedures (GBR) intend to regain the alveolar bone lost following tooth extraction and/or periodontal disease. Several biomaterials and surgical approaches have been proposed. In this paper we report biomaterials and surgical techniques used for periodontal and bone regenerative procedures. Particular attention will be adopted to highlight the biological basis for the different therapeutic approaches.


1985 ◽  
Vol 55 ◽  
Author(s):  
Jacob S. Hanker ◽  
Myron R. Tucker ◽  
Bill C. Terry ◽  
Reynolds A. Carnevale ◽  
Beverly L. Giammara

ABSTRACTSintered ceramic, nonresorbable hydroxylapatite (HA) is a calcium phosphate biomaterial widely employed alone for augmentation or maintenance of the mandibular ridge and for filling alveolar bony defects. The small particles used for ridge augmentation or periodontal defects tend to scatter and the larger blocks used for extraction sockets don't fit well. Our recent studies suggest that these problems can be circumvented by composite plaster of Paris/HA implants. In addition to binding the HA particles, the plaster makes the implants easier to shape. Plaster is not only very biocompatible but may actually help prevent infection. It appears to act as a scaffold for incorporation of the HA particles into osseous tissue. In several days the plaster is resorbed but it is replaced at the same rate by infiltrating fibrovascular tissue; plaster definitely promotes the filling of osseous defects initially by connective tissue. This tissue not only maintains the form and integrity of the implant, but its vascular and collagen components promote healing and contribute to subsequent filling of the defects and approximation of the HA particles by new cancellous bone. These composite implants can be preformed on casts prior to surgery or tailored during the surgical procedure. Their use precludes the difficulties encountered when plaster alone is implanted (resorption) or when HA alone is used (particle scatter or nonpenetration of the material by host vascular and connective tissues). By having a resorbable component which permits penetration by fibrovascular tissue and a nonresorbable component which can act as a nidus for new cancellous bone formation, these composite alloplasts act like artificial bone. Their use to support a denture, or for immobilizing teeth and reducing pocket depths in advanced periodontal disease, gives better results than HA alone.


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