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2021 ◽  
Vol 19 (4) ◽  
pp. 627-638
Author(s):  
Hye Jeong Koo ◽  
Ki Han Kwon

Purpose: This study intends to prove whether the efficacy already proven in the existing light therapy LED mask device is similarly exerted in the self-luminous LED sheet mask that does not require power.Methods: The experimental subjects of this study were women with an average age of 47.9 years, and the effect of improving 24-hour moisturizing lasting, skin elasticity, eye expression wrinkles, and facial (cheek) lifting was studied by prohibiting the use of cosmetics containing active ingredients that could affect the results and making them use an LED sheet type mask pack.Results: As a result of the experiment, the 24-hour moisturizing lasting power was 90.573% immediately after use and 37.384% after 24 hours, so it increased significantly (p<0.05), and skin elasticity was also increased by 7.087% immediately after use. After one week, it was increased significantly (p<0.025) to 11.181%. Expression wrinkles around the eyes were significantly reduced (p<0.05) to 1.621% immediately after use and 4.579% after 1 week of use. In the facial (cheek) lifting experiment, the cheek angle (°) was reduced to 2.065% immediately postuse compared to pre-use. Also, it was significantly decreased (p<0.05) with a result of 3.762% after 1 week of use, thus proving that the light therapy LED sheet mask is also effective for skin improvement.Conclusion: Using this research material as basic data, it is expected that various skincare products will be developed as well as mask packs with a simple and easy structure of effective light therapy.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
José Antonio Santoyo-Ramón ◽  
Eduardo Casilari-Pérez ◽  
José Manuel Cano-García

AbstractWearable Fall Detection Systems (FDSs) have gained much research interest during last decade. In this regard, Machine Learning (ML) classifiers have shown great efficiency in discriminating falls and conventional movements or Activities of Daily Living (ADLs) based on the analysis of the signals captured by transportable inertial sensors. Due to the intrinsic difficulties of training and testing this type of detectors in realistic scenarios and with their target audience (older adults), FDSs are normally benchmarked against a predefined set of ADLs and emulated falls executed by volunteers in a controlled environment. In most studies, however, samples from the same experimental subjects are used to both train and evaluate the FDSs. In this work, we investigate the performance of ML-based FDS systems when the test subjects have physical characteristics (weight, height, body mass index, age, gender) different from those of the users considered for the test phase. The results seem to point out that certain divergences (weight, height) of the users of both subsets (training ad test) may hamper the effectiveness of the classifiers (a reduction of up 20% in sensitivity and of up to 5% in specificity is reported). However, it is shown that the typology of the activities included in these subgroups has much greater relevance for the discrimination capability of the classifiers (with specificity losses of up to 95% if the activity types for training and testing strongly diverge).


2021 ◽  
pp. 016224392110570
Author(s):  
Samantha Vanderslott ◽  
Alexandra Palmer ◽  
Tonia Thomas ◽  
Beth Greenhough ◽  
Arabella Stuart ◽  
...  

Preclinical (animal) testing and human testing of drugs and vaccines are rarely considered by social scientists side by side. Where this is done, it is typically for theoretically exploring the ethics of the two situations to compare relative treatment. In contrast, we empirically explore how human clinical trial participants understand the role of animal test subjects in vaccine development. Furthermore, social science research has only concentrated on broad public opinion and the views of patients about animal research, whereas we explore the views of a public group particularly implicated in pharmaceutical development: experimental subjects. We surveyed and interviewed COVID-19 vaccine trial participants in Oxford, UK, on their views about taking part in a vaccine trial and the role of animals in trials. We found that trial participants mirrored assumptions about legitimate reasons for animal testing embedded in regulation and provided insight into (i) the nuances of public opinion on animal research; (ii) the co-production of human and animal experimental subjects; (iii) how vaccine and medicine testing, and the motivations and demographics of clinical trial participants, change in an outbreak; and (iv) what public involvement can offer to science.


2021 ◽  
Vol 33 (5) ◽  
pp. 1013-1028
Author(s):  
Kenta Higashi ◽  
Naoya Isoyama ◽  
Nobuchika Sakata ◽  
Kiyoshi Kiyokawa ◽  

Interpersonal communication is so important in everyday life that it is desirable everyone who participates in the conversation is satisfied. However, every participant of the conversation cannot be satisfied in such cases as those wherein only one person cannot keep up with the conversation and feels alienated, or wherein someone cannot communicate non-verbal expressions with his/her conversation partner adequately. In this study, we have focused on facial direction and gaze among the various factors that are said to affect conversational satisfaction. We have attempted to lessen any sense of non-participation in the conversation and increase the conversational satisfaction of the non-participant in a tripartite conversation by modulating the visual information in such a way that the remaining two parties turn toward the non-participating party. In the experiments we have conducted in VR environments, we have reproduced a conversation of two male adults recorded in actual environments using two avatars. The experimental subjects have watched this over their HMDs. The experiments have found that visually modulating the avatars’ faces and gazes such that they appear to turn toward the subjects has increased the subjects’ sense of participation in the conversation. Nevertheless, the experiments have not increased the subjects’ conversational enjoyment, a component of the factors for conversational satisfaction.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Wang Li ◽  
Xin Cheng ◽  
Xian Feng Cai

To realize the remote monitoring design in the process of rehabilitation training for athletes after an injury using computer technology, using Visual Studio 2010 development platform, and using ASP as the development language, NET as the development framework, the injury rehabilitation of injured athletes for dynamic monitoring of information management system, and its functions, system architecture and other detailed design. This article identified six laboratory workers outside the sample as experimental subjects. The experimental subjects’ blood oxygen flow, degree, and rate were measured in the normal condition, and the pulse wave was recorded. Then, the upper and lower limbs rehabilitation training robot developed by the laboratory was used for about 15 minutes of rehabilitation training with 3-gear difficulty. The results show that the data measured by the system are the same as the data measured by the Lu Yue brand finger clip type YX301 blood oxygen saturation detector and meet the design requirements. Conclusion. The monitoring accuracy of the system is high, the resistance signal waveform is basically consistent with the actual waveform, and the monitoring effect is good.


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Anping Li ◽  
Hongfei Wu ◽  
Yuan Liu

The fluctuation of martial arts athletes before competition is easy to affect martial arts competition. Emotional stimulation helps martial arts athletes to play in the competition field and improve their on-the-sport coping skills. In this paper, we use artificial intelligence technology to analyze the precompetition emotions of martial arts athletes, make guidance for the precompetition situation of martial arts athletes, and give to-the-spot response guidance and suggestions. In this paper, the artificial intelligence MLR (multiple logistic regression) combined with the unsupervised LOF (local outlier factor) algorithm is used to realize the precompetition emotion analysis and on-the-spot response guidance for martial arts athletes. In addition, this paper takes a community martial arts team as the test object and verifies the method through practice feedback. Studies have shown that this method of analysis and guidance can effectively assess the emotions of martial arts athletes and take intervention, compared to the absence of sentiment analysis and on-the-sport guidance for martial arts athletes. Compared to the coach’s intuitive guidance, the interventions in this treatise speed up 65%. From the experimental subjects in this paper, athletes of the same level provide emotional guidance and suggestions for responding to emotional fluctuations. This can psychologically improve the efficiency of athletes by more than 35%. Therefore, the use of artificial intelligence analysis methods can effectively improve the emotional stability of martial arts athletes before the game, so that they can deal with all kinds of emergencies on the spot.


2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Bingbing Yan ◽  
Chuanying Zhang

With the continuous popularization of smart medicine, the protective effect of silibinin in the liver has attracted much attention. This study mainly explores the liver protection mechanism and absorption promotion technology of silybin based on intelligent medical analysis. Refining of silibinin: accurately weigh 1.0 g of silibinin in a three-necked flask; gradually add 50 mL of anhydrous methanol, reflux and filter the precipitated solid; and weigh it after drying. ICR male mice were taken as experimental subjects and randomly divided into groups of 10 each. The mice in the normal group and the model group were given intragastrically with 0.5% CMC-Na solution; the mice in the silibinin group were given intragastrically with SB/CMC-Na suspension; the mice in the remaining groups were given low, medium, and high-dose suspensions to their stomachs, and silibinin 23 acylate/CMC-Na suspension was administered at a dose of 10 mL/kg for 7 consecutive days. After that, the mice were fasted for 12 hours. After 6 hours of fasting (18 hours after modeling), the blood cells from their orbits were taken, placed in a 37°C water bath for 30 minutes, and centrifuged at 4000 rpm for 10 minutes, and then the serum was taken; the activity equivalent of AST and ALT in serum was measured; serum determination Medium AST and ALT vitality. The mice were killed by decapitation, fresh liver tissue was immediately collected, and part of it was frozen in liquid nitrogen for the RT-PCR test. The hepatocyte expansion and death were observed using a transmission electron microscope, and the oncosis index (OI) was calculated. Another part of the liver tissue was fixed in 4% paraformaldehyde solution, embedded in paraffin, dehydrated, and sliced at 4 μm. Some sections were stained with conventional HE, and the pathological changes of liver cells were observed under light microscope; some sections were subjected to immunohistochemistry. Only one mouse died when 240 mg/kg of silibinin was given 10 minutes after the model was modeled. However, when 240 mg/kg silibinin was given to the mice 20 minutes after modeling, the mortality rate of the mice rose to 50%, and the therapeutic effect was significantly weakened. This research is helpful to advance the research of silybin in liver protection.


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