Early wound bed preparation: irrigation and debridement

Pressure ulcer or pressure sore is one of the complications seen in bedridden patients. Management of these ulcers is often challenging. But there is no well-established method that accelerates the wound healing rate. Various adjunctive methods are used for wound bed preparation before definitive reconstruction plan is made. Here we describe our experience in the role of insulin therapy as an adjunct in the management of pressure sores.

Download Full-text

Early Wound Cover of Gunshot Injury to the Leg with Free Composite Anterolateral Thigh Flap: a Case Report

SN Comprehensive Clinical Medicine ◽

10.1007/s42399-020-00681-7 ◽

2021 ◽

Author(s):

Raman Sharma ◽

Jerry R John ◽

Ramesh Kumar Sharma ◽

Raghavendra Kaladagi

Keyword(s):

Case Report ◽

Gunshot Injury ◽

Anterolateral Thigh Flap ◽

Anterolateral Thigh ◽

Early Wound

Download Full-text

Unit 4. Wound bed preparation

Practice Nursing ◽

10.12968/pnur.2011.22.11.cpd4 ◽

2011 ◽

Vol 22 (11) ◽

pp. 1-4

Author(s):

Karen Ousey ◽

Caroline McIntosh

Keyword(s):

Wound Bed Preparation

Download Full-text

The Influence of Obesity on Treatment and Outcome of Severely Burned Patients

Journal of Burn Care & Research ◽

10.1093/jbcr/irz115 ◽

2019 ◽

Vol 40 (6) ◽

pp. 996-1008 ◽

Cited By ~ 1

Author(s):

Christian Tapking ◽

Khosrow S Houschyar ◽

Victoria G Rontoyanni ◽

Gabriel Hundeshagen ◽

Karl-Friedrich Kowalewski ◽

...

Keyword(s):

Fluid Resuscitation ◽

Chronic Conditions ◽

Perioperative Management ◽

Normal Weight ◽

Burn Patients ◽

Obese Patients ◽

Nonalcoholic Fatty Liver ◽

Wound Coverage ◽

Severe Burns ◽

Early Wound

Abstract Obesity and the related medical, social, and economic impacts are relevant multifactorial and chronic conditions that also have a meaningful impact on outcomes following a severe injury, including burns. In addition to burn-specific difficulties, such as adequate hypermetabolic response, fluid resuscitation, and early wound coverage, obese patients also present with common comorbidities, such as arterial hypertension, diabetes mellitus, or nonalcoholic fatty liver disease. In addition, the pathophysiologic response to severe burns can be enhanced. Besides the increased morbidity and mortality compared to burn patients with normal weight, obese patients present a challenge in fluid resuscitation, perioperative management, and difficulties in wound healing. The present work is an in-depth review of the current understanding of the influence of obesity on the management and outcome of severe burns.

Download Full-text

Cell cycle controls and the role of nerves and the regenerate epithelium in urodele forelimb regeneration: possible modifications of basic concepts

Biochemistry and Cell Biology ◽

10.1139/o87-097 ◽

1987 ◽

Vol 65 (8) ◽

pp. 739-749 ◽

Cited By ~ 17

Author(s):

Roy A. Tassava ◽

David J. Goldhamer ◽

Bruce L. Tomlinson

Keyword(s):

Cell Cycle ◽

Monoclonal Antibody ◽

Limb Regeneration ◽

Blastema Formation ◽

Basic Concepts ◽

Regenerate Epithelium ◽

Early Wound ◽

Skin Epidermis ◽

Wound Epithelium

Data from pulse and continuous labeling with [3H]thymidine and from studies with monoclonal antibody WE3 have led to the modification of existing models and established concepts pertinent to understanding limb regeneration. Not all cells of the adult newt blastema are randomly distributed and actively progressing through the cell cycle. Instead, many cells are in a position that we have designated transient quiescence (TQ) and are not actively cycling. We postulate that cells regularly leave the TQ population and enter the actively cycling population and vice versa. The size of the TQ population may be at least partly determined by the quantity of limb innervation. Larval Ambystoma may have only a small or nonexisting TQ, thus accounting for their rapid rate of regeneration. Examination of reactivity of monoclonal antibody WE3 suggests that the early wound epithelium, which is derived from skin epidermis, is later replaced by cells from skin glands concomitant with blastema formation. WE3 provides a useful tool to further investigate the regenerate epithelium.

Download Full-text

Penetrating deep pelvic injury due to “less-lethal” beanbag munitions: a case report and policy implications

Trauma Surgery & Acute Care Open ◽

10.1136/tsaco-2021-000754 ◽

2021 ◽

Vol 6 (1) ◽

pp. e000754

Author(s):

Christopher S Schenck ◽

Soum D Lokeshwar ◽

Matthew D Riedel ◽

Kimberly A Davis

Keyword(s):

Pelvic Abscess ◽

Policy Implications ◽

Severe Injury ◽

Pelvic Injury ◽

Surgical Removal ◽

Delayed Presentation ◽

Permanent Disability ◽

Irrigation And Debridement ◽

Excellent Functional Outcome ◽

Serious Injury

“Less-lethal” munitions are designed to cause incapacitation and are often used by law enforcement officers. Although these munitions are not designed to cause severe injury, recent reports have demonstrated that they can cause severe injury, permanent disability, and death. The long-term consequences of injury due to less-lethal munitions are not well understood. We present a case of osteomyelitis and pelvic abscess secondary to a retained beanbag munition following penetrating injury in the setting of a patient with delayed presentation for care. The patient underwent surgical removal of the retained beanbag munition and irrigation and debridement of the osteomyelitis and pelvic abscess with an excellent functional outcome. We discuss the public health and policy implications of serious injury due to less-lethal munitions.

Download Full-text