scholarly journals Therapeutic Efficacy and Safety of GH in Japanese Children with Down Syndrome Short Stature Accompanied by GH Deficiency

2013 ◽  
Vol 22 (4) ◽  
pp. 65-72 ◽  
Author(s):  
Kyoko Meguri ◽  
Masaru Inoue ◽  
Koji Narahara ◽  
Takahiro Sato ◽  
Ami Takata ◽  
...  
2017 ◽  
Vol 61 (2) ◽  
pp. 146-152 ◽  
Author(s):  
Tomomi Niegawa ◽  
Kimitaka Takitani ◽  
Ryuzo Takaya ◽  
Manabu Ishiro ◽  
Yuichi Kuroyanagi ◽  
...  

1990 ◽  
Vol 12 (6) ◽  
pp. 164-190

Down syndrome is the most common chromosomal abnormality associated with short stature. Recent studies have indicated that infancy and adolescence are the periods where growth is affected most severely. Compared with normal standards for children without Down syndrome, growth rates of children with Down syndrome are reduced by 20% between ages 3 and 36 months, by 5 to 10% in childhood, and by 27% (girls) and 50% (boys) during adolescence. Reduction in lower segment length (pubis to floor) appears to be the major contributor to the decreased growth seen in children with Down syndrome. Average adult heights are 145 cm in women and 152.5 cm in men.


2018 ◽  
Vol 62 (2) ◽  
pp. 231-236
Author(s):  
Junna Horio ◽  
Hiroki Kaneko ◽  
Kei Takayama ◽  
Kinichi Tuzuki ◽  
Hiroko Kakihara ◽  
...  

2001 ◽  
Vol 88 (3_suppl) ◽  
pp. 1096-1098 ◽  
Author(s):  
Su-Fen Huang ◽  
Manabu Oi

In an extension of maternal question-asking to Japanese children during free play and at meal time each of 20 mother-child dyads was videotaped at home. The mothers of children with Down syndrome asked more questions during free play, at meal time, and for the sum of these two. Also, they produced more requests for information during free play and for combined conditions and fewer clarification requests during free play. The results were compared to those of the previous study of Taiwanese mothers.


2018 ◽  
Vol Volume 12 ◽  
pp. 1637-1643
Author(s):  
Tomoko Terai ◽  
Shohei Eda ◽  
Jun Sugasawa ◽  
Masahiro Tonari ◽  
Junko Matsuo ◽  
...  

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