scholarly journals Chemical composition and laboratory investigation of Melissa officinalis essential oil against human malarial vector mosquito, Anopheles stephensi L. (Diptera: Culicidae)

2016 ◽  
Vol 4 (12) ◽  
pp. 969-973 ◽  
Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1081
Author(s):  
Matilda Rădulescu ◽  
Călin Jianu ◽  
Alexandra Teodora Lukinich-Gruia ◽  
Marius Mioc ◽  
Alexandra Mioc ◽  
...  

The investigation aimed to study the in vitro and in silico antioxidant properties of Melissa officinalis subsp. officinalis essential oil (MOEO). The chemical composition of MOEO was determined using GC–MS analysis. Among 36 compounds identified in MOEO, the main were beta-cubebene (27.66%), beta-caryophyllene (27.41%), alpha-cadinene (4.72%), caryophyllene oxide (4.09%), and alpha-cadinol (4.07%), respectively. In vitro antioxidant properties of MOEO have been studied in 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging, and inhibition of β-carotene bleaching assays. The half-maximal inhibitory concentration (IC50) for the radical scavenging abilities of ABTS and DPPH were 1.225 ± 0.011 μg/mL and 14.015 ± 0.027 μg/mL, respectively, demonstrating good antioxidant activity. Moreover, MOEO exhibited a strong inhibitory effect (94.031 ± 0.082%) in the β-carotene bleaching assay by neutralizing hydroperoxides, responsible for the oxidation of highly unsaturated β-carotene. Furthermore, molecular docking showed that the MOEO components could exert an in vitro antioxidant activity through xanthine oxidoreductase inhibition. The most active structures are minor MOEO components (approximately 6%), among which the highest affinity for the target protein belongs to carvacrol.


2012 ◽  
Vol 22 (1) ◽  
pp. 40-44 ◽  
Author(s):  
Ana Carolina B. Sodré ◽  
José Magno Q. Luz ◽  
Lenita L. Haber ◽  
Marcia O. M. Marques ◽  
Carlos R. Rodrigues ◽  
...  

Author(s):  
Thaís C. Silva ◽  
Suzan K.V. Bertolucci ◽  
Alexandre A. Carvalho ◽  
Wesley N. Tostes ◽  
Ivan C.A. Alvarenga ◽  
...  

2020 ◽  
Vol 14 (3) ◽  
pp. 41-45 ◽  
Author(s):  
Montero Fernández Ismael ◽  
Rômulo Estevam Ribeiro Pedro ◽  
Antonio Saravia Maldonado Selvin ◽  
Perpetua Ferraz Vany ◽  
Santos Alemán Ricardo ◽  
...  

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