Melissa officinalis L. subsp. altissima (Sibth. & Sm.) Arcang. essential oil: Chemical composition and preliminary antimicrobial investigation of samples obtained at different harvesting periods and by fractionated extractions

2018 ◽  
Vol 117 ◽  
pp. 317-321 ◽  
Author(s):  
Mijat Božović ◽  
Stefania Garzoli ◽  
Anna Baldisserotto ◽  
Carlo Romagnoli ◽  
Federico Pepi ◽  
...  
Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1081
Author(s):  
Matilda Rădulescu ◽  
Călin Jianu ◽  
Alexandra Teodora Lukinich-Gruia ◽  
Marius Mioc ◽  
Alexandra Mioc ◽  
...  

The investigation aimed to study the in vitro and in silico antioxidant properties of Melissa officinalis subsp. officinalis essential oil (MOEO). The chemical composition of MOEO was determined using GC–MS analysis. Among 36 compounds identified in MOEO, the main were beta-cubebene (27.66%), beta-caryophyllene (27.41%), alpha-cadinene (4.72%), caryophyllene oxide (4.09%), and alpha-cadinol (4.07%), respectively. In vitro antioxidant properties of MOEO have been studied in 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging, and inhibition of β-carotene bleaching assays. The half-maximal inhibitory concentration (IC50) for the radical scavenging abilities of ABTS and DPPH were 1.225 ± 0.011 μg/mL and 14.015 ± 0.027 μg/mL, respectively, demonstrating good antioxidant activity. Moreover, MOEO exhibited a strong inhibitory effect (94.031 ± 0.082%) in the β-carotene bleaching assay by neutralizing hydroperoxides, responsible for the oxidation of highly unsaturated β-carotene. Furthermore, molecular docking showed that the MOEO components could exert an in vitro antioxidant activity through xanthine oxidoreductase inhibition. The most active structures are minor MOEO components (approximately 6%), among which the highest affinity for the target protein belongs to carvacrol.


2012 ◽  
Vol 22 (1) ◽  
pp. 40-44 ◽  
Author(s):  
Ana Carolina B. Sodré ◽  
José Magno Q. Luz ◽  
Lenita L. Haber ◽  
Marcia O. M. Marques ◽  
Carlos R. Rodrigues ◽  
...  

Author(s):  
Thaís C. Silva ◽  
Suzan K.V. Bertolucci ◽  
Alexandre A. Carvalho ◽  
Wesley N. Tostes ◽  
Ivan C.A. Alvarenga ◽  
...  

2020 ◽  
Vol 14 (3) ◽  
pp. 41-45 ◽  
Author(s):  
Montero Fernández Ismael ◽  
Rômulo Estevam Ribeiro Pedro ◽  
Antonio Saravia Maldonado Selvin ◽  
Perpetua Ferraz Vany ◽  
Santos Alemán Ricardo ◽  
...  

2018 ◽  
Vol 8 (4) ◽  
pp. 213-218
Author(s):  
Haleh Mohamadpoor ◽  
Abdollah Ghasemi Pirbalouti ◽  
Fatemeh Malekpoor ◽  
Behzad Hamedi

2014 ◽  
Vol 9 (5) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Renata Nurzyńska-Wierdak ◽  
Anna Bogucka-Kocka ◽  
Grażyna Szymczak

The present study investigated changes in the content and chemical composition of the essential oil extracted by hydrodistillation from air-dried Melissa officinalis L. (lemon balm) leaves in the first and second year of plant growth. The lemon balm oil was analysed by GC-MS and GC-FID. The presence of 106 compounds, representing 100% of the oil constituents, was determined in the oil. The predominant components were geranial (45.2% and 45.1%) and neral (32.8% and 33.8%); their proportions in the examined samples of the oil obtained from one- and two-year-old plants were comparable. However, the age of lemon balm plants affected the concentration of other constituents and the proportions of the following compounds were subject to especially high fluctuations: citronellal (8.7% and 0.4%), geraniol (trace amounts and 0.6%), and geranyl acetate (0.5% and 3.0%), as well as, among others, isogeranial, E-caryophyllene, caryophyllene oxide, germacrene D, and carvacrol. The essential oil of two-year-old plants was characterized by a richer chemical composition than the oil from younger plants.


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