1A15 A numerical simulation of rolling and adhesion of red blood cells infected by malaria

2015 ◽  
Vol 2015.27 (0) ◽  
pp. 11-12
Author(s):  
Yuki ICHIKAWA ◽  
Yohsuke IMAI ◽  
Daiki MATSUNAGA ◽  
Stephanie NIX ◽  
Takuji ISHIKAWA ◽  
...  
Keyword(s):  
Numerical Simulation ◽  
Red Blood Cells ◽  
Blood Cells

Time-Dependent Diffusion in the Alveolar Region of the Lungs: Effect of Moving Red Blood Cells

2002 ◽  
Author(s):  
A. A. Merrikh ◽  
J. L. Lage
Keyword(s):  
Numerical Simulation ◽  
Blood Plasma ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Gas Diffusion ◽  
Physical Parameters ◽  
Liquid Region ◽  
Diffusing Capacity ◽  
Alveolar Region ◽  
Capillary Membranes

Results from a preliminary numerical simulation of alveolar gas diffusion with moving capillary red blood cells (RBCs) are presented. The alveolar region is modeled with four basic constituents, namely the alveolus (or gas region), the tissue (a region lumping the alveolar and capillary membranes, and the interstitial fluid), the blood plasma (a liquid region) and the RBCs. A single, straight capillary with equally spaced RBCs moving together with the blood plasma is considered in this preliminary study. The numerical simulation attempts also to mimic the time-varying gas concentration in the alveolus region due to respiration. Realistic physical parameters (e.g., dimensions, diffusivities and RBCs speed) are used for simulating CO diffusion, in accordance to clinical tests for determining the lung diffusing capacity. Results are compared to published results obtained when the RBCs are fix in place (stationary). The RBCs moving effect, relevant at high hematocrit, is to increase the resulting lung diffusing capacity.

Sign in / Sign up

Export Citation Format

Share Document