scholarly journals 342 Real-time Measurement of Dynamic Stiffness on the Body Surface Using Self-Excited Vibration Generated by Positive Feedback of the Velocity : Improvement of Response and Accuracy by the Kalman Filter

2008 ◽  
Vol 2008 (0) ◽  
pp. _342-1_-_342-6_
Author(s):  
Takayuki MIYAOKA ◽  
Yutaka KURITA ◽  
Yuichi MATSUMURA
Keyword(s):  
Kalman Filter ◽  
Real Time ◽  
Body Surface ◽  
Positive Feedback ◽  
Dynamic Stiffness ◽  
Time Measurement ◽  
The Body ◽  
Real Time Measurement ◽  
Excited Vibration

scholarly journals Real-time measurement of small molecules directly in awake, ambulatory animals

2017 ◽  
Vol 114 (4) ◽  
pp. 645-650 ◽  
Author(s):  
Netzahualcóyotl Arroyo-Currás ◽  
Jacob Somerson ◽  
Philip A. Vieira ◽  
Kyle L. Ploense ◽  
Tod E. Kippin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
High Resolution ◽  
Personalized Medicine ◽  
Small Molecules ◽  
Real Time ◽  
Controlled Drug Delivery ◽  
Time Measurement ◽  
The Body ◽  
Patient Specific ◽  
Real Time Measurement

The development of a technology capable of tracking the levels of drugs, metabolites, and biomarkers in the body continuously and in real time would advance our understanding of health and our ability to detect and treat disease. It would, for example, enable therapies guided by high-resolution, patient-specific pharmacokinetics (including feedback-controlled drug delivery), opening new dimensions in personalized medicine. In response, we demonstrate here the ability of electrochemical aptamer-based (E-AB) sensors to support continuous, real-time, multihour measurements when emplaced directly in the circulatory systems of living animals. Specifically, we have used E-AB sensors to perform the multihour, real-time measurement of four drugs in the bloodstream of even awake, ambulatory rats, achieving precise molecular measurements at clinically relevant detection limits and high (3 s) temporal resolution, attributes suggesting that the approach could provide an important window into the study of physiology and pharmacokinetics.

scholarly journals Live Demonstration: A Portable Microsensor Fusion System with Real-Time Measurement for On-Site Beverage Tasting

2019 ◽  
Author(s):  
Josep Maria Margarit-Taule ◽  
Pablo Gimenez-Gomez ◽  
Roger Escude-Pujol ◽  
Manuel Gutierrez-Capitan ◽  
Cecilia Jimenez-Jorquera ◽  
...  
Keyword(s):  
Real Time ◽  
Time Measurement ◽  
Fusion System ◽  
Real Time Measurement ◽  
Live Demonstration
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