Effect of Potential Shape on Mobility of Nonlinear Energy Localization

2019 ◽  
Vol 2019 (0) ◽  
pp. J22103
Author(s):  
Yusuke DOI ◽  
Akihiro NAKATANI
Keyword(s):  
Energy Localization ◽  
Potential Shape ◽  
Nonlinear Energy

Comments on Energy Harvesting on a 2:1 Internal Resonance Portal Frame Support Structure, Using a Nonlinear-Energy Sink as a Passive Controller

2016 ◽  
Vol 10 (3) ◽  
pp. 147 ◽  
Author(s):  
Rodrigo Tumolin Rocha ◽  
Jose Manoel Balthazar ◽  
Angelo Marcelo Tusset ◽  
Vinicius Piccirillo ◽  
Jorge Luis Palacios Felix
Keyword(s):  
Energy Harvesting ◽  
Internal Resonance ◽  
Nonlinear Energy Sink ◽  
Support Structure ◽  
Portal Frame ◽  
Energy Sink ◽  
Nonlinear Energy

The Yin and Yang of BK Channels in Epilepsy

2018 ◽  
Vol 17 (4) ◽  
pp. 272-279 ◽  
Author(s):  
Yudan Zhu ◽  
Shuzhang Zhang ◽  
Yijun Feng ◽  
Qian Xiao ◽  
Jiwei Cheng ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Bk Channels ◽  
Bk Channel ◽  
Potential Shape ◽  
Yin And Yang ◽  
The Central Nervous System ◽  
Action Potential Shape ◽  
Excitability Of Neurons

Background & Objective: The large conductance calcium-activated potassium (BK) channel, extensively distributed in the central nervous system (CNS), is considered as a vital player in the pathogenesis of epilepsy, with evidence implicating derangement of K+ as well as regulating action potential shape and duration. However, unlike other channels implicated in epilepsy whose function in neurons could clearly be labeled “excitatory” or “inhibitory”, the unique physiological behavior of the BK channel allows it to both augment and decrease the excitability of neurons. Thus, the role of BK in epilepsy is controversial so far, and a growing area of intense investigation. Conclusion: Here, this review aims to highlight recent discoveries on the dichotomous role of BK channels in epilepsy, focusing on relevant BK-dependent pro- as well as antiepileptic pathways, and discuss the potential of BK specific modulators for the treatment of epilepsy.

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