Synovial chondromatosis of the hip joint in a 6 year-old child: A case report

Introduction: Synovial chondromatosis is a rare synovial disorder characterized by the presence of benign loose bodies in the joint space. The affliction of the hip joint is rare. This entity usually goes undiagnosed as it is largely asymptomatic till complications such as secondary osteoarthritis secondary to degenerative changes, subluxation of hip, and fracture neck of femur ensue. Case Report: A 46-year-old farmer presented with a 9-year long history of the left hip pain with restriction in flexion, extension, and internal rotation. He was diagnosed with synovial chondromatosis and had a history of undergoing arthroscopic debridement following which he was asymptomatic but relapsed after 6 months. We performed excision with uncemented modular bipolar hemiarthroplasty after confirming the diagnosis on plain radiographs and computed tomography. Significant recovery in the range of motion was noted postoperatively and the patient showed no signs of relapse in the follow-up period of 18 months. Conclusion: Treatment of synovial chondromatosis of the hip joint poses a challenge due to its complex anatomy. Keywords: Synovial chondromatosis, arthroplasty, hip joint

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INTRA-ARTICULAR SYNOVIAL CHONDROMATOSIS: CLINICAL CASE REPORT

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ◽

10.1016/j.oooo.2019.06.377 ◽

2020 ◽

Vol 129 (1) ◽

pp. e91

Author(s):

LETÍCIA DRUMOND DE ABREU GUIMARÃES ◽

STEPHANIE KENIG VIVEIROS ◽

DANIEL UIEDA ◽

FABIO DAUMAS NUNES

Keyword(s):

Case Report ◽

Clinical Case ◽

Synovial Chondromatosis

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Phenylketonuria and juvenile idiopathic arthritis: a case report

BMC Pediatrics ◽

10.1186/s12887-021-02602-6 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Ting Ting Zhu ◽

Jin Wu ◽

Li Yuan Wang ◽

Xiao Mei Sun

Keyword(s):

Juvenile Idiopathic Arthritis ◽

Case Report ◽

Autoimmune Diseases ◽

Hip Joint ◽

Metabolic Disorder ◽

Rare Case ◽

Molecular Data ◽

Methotrexate Therapy ◽

Case Presentation

Abstract Background Phenylketonuria (PKU) is a genetic metabolic disorder in which patients have no ability to convert phenylalanine to tyrosine. Several autoimmune diseases have been reported to combine with PKU, co-existent of PKU and Juvenile Idiopathic Arthritis (JIA) has not been presented. Case presentation The girl was diagnosed with PKU at the age of 1 month confirmed by molecular data. At the age of 3.5 years, she presented with pain and swelling of her right ankle, right knee, and right hip joint. After a serial of examinations, she was diagnosed with JIA and treated with a nonsteroidal anti-inflammatory drug. Conclusions We report a rare case of a 4-year-old girl with PKU and JIA, which supports a possible interaction between PKU and JIA. Long-term metabolic disturbance may increase the susceptibility to JIA. Further chronic inflammation could alter the metabolism of tryptophan and tyrosine to increase blood Phe concentration. In addition, corticosteroid and methotrexate therapy for JIA may increase blood Phe concentration.

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