scholarly journals Investigating the Role of Respiratory Syncytial Virus and Influenza virus in Patients with Otitis Media with Effusion

2015 ◽  
Vol 8 (october Spl Edition) ◽  
pp. 739-746
Author(s):  
Hossein Rekabi ◽  
Nader Saki ◽  
Soheila Nikakhlagh ◽  
Vita Derakshandeh ◽  
Amir Niazi
Keyword(s):  
Influenza Virus ◽  
Respiratory Syncytial Virus ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Syncytial Virus

Detection of Genomic Sequences of Respiratory Syncytial Virus in Otitis Media with Effusion in Children

1992 ◽  
Vol 101 (10_suppl) ◽  
pp. 7-10 ◽  
Author(s):  
Yoshitaka Okamoto ◽  
Kazuo Kudo ◽  
Koji Shirotori ◽  
Misao Nakazawa ◽  
Eiko Ito ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Respiratory Syncytial Virus ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Chain Reaction ◽  
Nested Polymerase Chain Reaction ◽  
Rsv Infection ◽  
Polymerase Chain ◽  
Syncytial Virus ◽  
Viral Sequences

The reverse transcriptase—polymerase chain reaction and the nested polymerase chain reaction were used for detection of respiratory syncytial virus (RSV) sequences in middle ear effusions collected from children with otitis media. Sequences of RSV were detected in 21 of 34 samples tested. These samples were collected during and/or after natural outbreaks of RSV infection in the community. In those patients from whose nasopharynges RSV was isolated, the viral sequences were highly detectable (75%) in the effusions. These observations suggest RSV as an important factor in the pathogenesis of otitis media with effusion.

Genomic sequences of respiratory syncytial virus in otitis media with effusion

The Lancet ◽  
1991 ◽  
Vol 338 (8773) ◽  
pp. 1025-1026 ◽  
Author(s):  
Y. Okamoto ◽  
K. Shirotori ◽  
K. Kudo ◽  
E. Ito ◽  
K. Togawa ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Genomic Sequences ◽  
Syncytial Virus

The Role of Respiratory Syncytial Virus in Otitis Media in Children

1967 ◽  
Vol 63 (2-3) ◽  
pp. 445-454 ◽  
Author(s):  
B. Berglund ◽  
A. Salmivalli ◽  
J. A. Grönroos
Keyword(s):  
Respiratory Syncytial Virus ◽  
Otitis Media ◽  
Syncytial Virus

scholarly journals Role of respiratory syncytial virus in acute otitis media: Implications for vaccine development

Vaccine ◽  
2007 ◽  
Vol 25 (9) ◽  
pp. 1683-1689 ◽  
Author(s):  
Janak A. Patel ◽  
Dang T. Nguyen ◽  
Krystal Revai ◽  
Tasnee Chonmaitree
Keyword(s):  
Respiratory Syncytial Virus ◽  
Otitis Media ◽  
Vaccine Development ◽  
Acute Otitis Media ◽  
Syncytial Virus

scholarly journals Respiratory Syncytial Virus–associated Acute Otitis Media in Infants and Children

2020 ◽  
Vol 9 (5) ◽  
pp. 544-550
Author(s):  
Matthew Phillips ◽  
Lyn Finelli ◽  
Lisa Saiman ◽  
Chengbin Wang ◽  
Yoonyoung Choi ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Otitis Media ◽  
Acute Otitis Media ◽  
The United States ◽  
Future Research ◽  
Research Strategies ◽  
Syncytial Virus ◽  
The Impact ◽  
In Infants And Children

Abstract Despite recent declines in the incidence of acute otitis media (AOM), more than 5 million cases and 5–6 million primary AOM visits still occur in young children in the United States, resulting in $4.4 billion direct medical costs annually. Our aims in this review are to describe the role of respiratory syncytial virus (RSV) in the etiology of AOM, discuss the prospect of prevention of RSV-associated AOM through immunization, and suggest future research strategies to assess the impact of immunization on RSV-associated AOM.

Incidence of Adenovirus and Respiratory Syncytial Virus in Chronic Otitis Media with Effusion Using the Polymerase Chain Reaction

1995 ◽  
Vol 113 (3) ◽  
pp. 234-241 ◽  
Author(s):  
Collie B. Shaw ◽  
Neal Obermyer ◽  
Stephen J. Wetmore ◽  
George A. Spirou ◽  
R. Wesley Farr
Keyword(s):  
Polymerase Chain Reaction ◽  
Respiratory Syncytial Virus ◽  
Otitis Media ◽  
Middle Ear ◽  
Otitis Media With Effusion ◽  
Chronic Otitis Media ◽  
Chain Reaction ◽  
Viral Culture ◽  
Polymerase Chain ◽  
Syncytial Virus

The aim of this study is to investigate the role of adenovirus and respiratory syncytial virus in the cause of chronic otitis media with effusion by use of the polymerase chain reaction for detection. The polymerase chain reaction has proved to be more sensitive and specific than viral cultures and immunoassays in the detection of viruses in other specimens. Adenovirus and respiratory syncytial virus were chosen because these viruses have been the most commonly isolated viruses in middle ear effusions in studies using other techniques. The effusions (132 total) were sterilely collected from 88 children undergoing myringotomy and ventilation tube placement for chronic otitis media with effusion. Nine (6.8%) specimens were positive for adenovirus by the polymerase chain reaction, and 13 (9.9%) were positive for respiratory syncytial virus by the polymerase chain reaction. Only one specimen was positive for adenovirus and respiratory syncytial virus by viral culture and immunofluorescence, respectively. Our results show that the polymerase chain reaction can be used to detect adenovirus and respiratory syncytial virus in chronic middle ear effusions and that PCR is more sensitive than viral culture and immunofluorescence techniques.

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