Introduction. There are no guidelines for treating bacterial infections in
our country. Antibacterial drugs are selected empirically, which is not
always in accordance with the recommended therapy coming from the countries
that have their own pharmacotherapy protocols. This study reviews the
differences between the standard conservative treatment of
cholangitis/cholecystitis and treatment implemented in accordance with
current pharmacotherapy guidelines of other countries. The assessment of the
therapeutic efficacy of antibacterial drugs implemented in the treatment of
cholangitis/cholecystitis and economic viability of that implementation was
one of the aims of this study, and another one was comparison of the
efficiency and cost of medical treatment using physician?s therapy of choice
and treatment according to pharmacotherapy guidelines. Material and Methods.
The study was carried out over a threeyear period at the Department of
Infectious Diseases of the Clinical Center of Vojvodina. It included 72
patients with the diagnosis of cholangitis/cholecystitis who were divided
into two groups. The control group was treated according to the physician?s
therapy of choice, while the test group was treated in accordance with
pharmacotherapy guidelines. The efficiency and cost of medical treatment were
determined for both groups. Results. The comparison of the efficiency and
costs of medical treatment of cholangitis/cholecystitis before and after
introducing pharmacotherapy guidelines showed no significant differences in
the efficiency of administered therapies. However, the cost of medical
treatment carried out in accordance with pharmacotherapy guidelines showed a
decrease of 17.24%. Conclusion. Medical treatment using physician?s
antibacterial therapy of choice and the one which is in accordance with
pharmacotherapy guidelines for treating cholangitis/cholecystitis show no
differences in terms of efficiency. However, medical treatment proved to be
more affordable in the group of patients treated in accordance with
pharmacotherapy guidelines of other countries.