scholarly journals Genetic Variation in Sex Hormone Genes Influences Heel Ultrasound Parameters in Middle-Aged and Elderly Men: Results From the European Male Aging Study (EMAS)

2009 ◽  
Vol 24 (2) ◽  
pp. 314-323 ◽  
Author(s):  
Kate L Limer ◽  
Stephen R Pye ◽  
Wendy Thomson ◽  
Steven Boonen ◽  
Herman Borghs ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Sex Hormone ◽  
Middle Aged ◽  
Elderly Men ◽  
Aging Study ◽  
Heel Ultrasound ◽  
Ultrasound Parameters

scholarly journals Active Vitamin D (1,25-Dihydroxyvitamin D) and Bone Health in Middle-Aged and Elderly Men: The European Male Aging Study (EMAS)

2013 ◽  
Vol 98 (3) ◽  
pp. 995-1005 ◽  
Author(s):  
Dirk Vanderschueren ◽  
Stephen R. Pye ◽  
Terence W. O'Neill ◽  
David M. Lee ◽  
Ivo Jans ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Health ◽  
Active Vitamin ◽  
Middle Aged ◽  
Elderly Men ◽  
Dihydroxyvitamin D ◽  
1,25 Dihydroxyvitamin D ◽  
Active Vitamin D ◽  
Aging Study

scholarly journals Serum sex hormone and plasma homocysteine levels in middle-aged and elderly men

2006 ◽  
Vol 155 (6) ◽  
pp. 887-893 ◽  
Author(s):  
Hamid Reza Nakhai Pour ◽  
Diederick E Grobbee ◽  
Majon Muller ◽  
Marielle Emmelot-Vonk ◽  
Yvonne T van der Schouw
Keyword(s):  
Creatinine Clearance ◽  
Visceral Fat ◽  
Linear Regression Analysis ◽  
Plasma Homocysteine ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Total Testosterone ◽  
Middle Aged ◽  
Elderly Men ◽  
Fasting Plasma

Objective: To investigate whether circulating levels of testosterone (total, bioavailable), estradiol (total, bioavailable), and DHEA sulfate (DHEAS) are associated with fasting plasma homocysteine (tHcy) levels in middle-aged and elderly men. Design: A population-based sample of 400 independently living men between 40 and 80 years of age in a cross-sectional study. Methods: Total testosterone, sex hormone binding globulin (SHBG), and total estradiol were measured by RIA methods and bioavailable testosterone and estradiol were calculated. DHEAS was measured using an immunometric technique. Fasting homocysteine was measured by fluorescence polarization immunoassay. Anthropometric characteristics were also measured and two standardized questionnaires completed, including life-style factors and diet. Linear regression analysis adjusted for age, body mass index (BMI), creatinine clearance, and mean visceral fat was used to assess the association of endogenous sex hormones and fasting plasma homocysteine levels. Results: After adjustment for age, BMI, creatinine clearance, and mean visceral fat no statistically significant association was observed between testosterone (total, bioavailable), DHEAS, and estradiol (total, bioavailable)levels with natural log tHcy (β = −2 × 10−3; 95% confidence intervals (CI) −9 × 10−3; 5 × 10−3), (β = −4 × 10−3; 95% CI −18 × 10−3; 9 × 10−3), (β = 3 × 10−3; 95% CI −6 × 10−3; 12 × 10−3), (β = −9.3 × 10−5; 95% CI −1 × 10−3; 1 × 10−3), and (β = 0.00; 95% CI −3 × 10−3; 2 × 10−3) respectively. Additional adjustment for smoking, alcohol intake, daily physical activity, diabetes mellitus, and hypertension did not change these findings. Conclusion: The results of our study do not support a direct role for circulating sex hormone levels in the regulation of fasting plasma tHcy concentrations in middle-aged and elderly men.

scholarly journals Relationship between ED and depression among middle-aged and elderly men in Korea: Hallym aging study

2011 ◽  
Vol 23 (5) ◽  
pp. 227-234 ◽  
Author(s):  
J-Y Jeong ◽  
S K Lee ◽  
Y-W Kang ◽  
S-N Jang ◽  
Y J Choi ◽  
...  
Keyword(s):  
Middle Aged ◽  
Elderly Men ◽  
Aging Study
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