scholarly journals Development and Characterization of Conditionally Immortalized Osteoblast Precursor Cell Lines from Human Bone Marrow Stroma

1998 ◽  
Vol 13 (2) ◽  
pp. 205-217 ◽  
Author(s):  
Kevin C. Hicok ◽  
Thierry Thomas ◽  
Francesca Gori ◽  
David J. Rickard ◽  
Thomas C. Spelsberg ◽  
...  
Author(s):  
Detlef Van der Velde-Zimmermann ◽  
Veronique A. J. Smits ◽  
Marina A. M. Verdaasdonk ◽  
Louk H. P. M. Rademakers ◽  
Naomi Werner ◽  
...  

Stem Cells ◽  
1994 ◽  
Vol 12 (6) ◽  
pp. 638-649 ◽  
Author(s):  
A. Ferrajoli ◽  
M. Talpaz ◽  
N. G. Ordonez ◽  
E. R. Stanley ◽  
C. Hirsch-Ginsberg ◽  
...  

1997 ◽  
Vol 230 (1) ◽  
pp. 111-120 ◽  
Author(s):  
D. Van der Velde-Zimmermann ◽  
M.A.M. Verdaasdonk ◽  
L.H.P.M. Rademakers ◽  
R.A. De Weger ◽  
J.G. Van den Tweel ◽  
...  

1984 ◽  
Vol 71 (2) ◽  
pp. 73-80 ◽  
Author(s):  
Vito L. Burgio ◽  
Umberto Magrini ◽  
Laura Ciardelli ◽  
Gabriella Pezzoni

1999 ◽  
Vol 343 (3) ◽  
pp. 663 ◽  
Author(s):  
Karen P. SCHOFIELD ◽  
John T. GALLAGHER ◽  
Guido DAVID

2008 ◽  
Vol 466 (5) ◽  
pp. 1047-1053 ◽  
Author(s):  
Ching-Hua Yeh ◽  
Je-Ken Chang ◽  
Yan-Hsiung Wang ◽  
Mei-Ling Ho ◽  
Gwo-Jaw Wang

1981 ◽  
Vol 50 (1) ◽  
pp. 281-297
Author(s):  
M. Lanotte ◽  
T.D. Allen ◽  
T.M. Dexter

Morphological, enzymic and antigenic data are presented regarding a human bone-marrow stromal cell line maintained for 10 months and subcultured weekly. The main characteristics are a fibroblastoid morphology, diffuse growth in collagen gels, no colony formation in soft gel media, contact inhibition of growth and conversion to adipocytes when treated with hydrocortisone. The cells are non-phagocytic and membrane Fc receptors (i.e. aggregated human immunoglobulin G receptors) are absent, but they show diffuse cytoplasmic non-specific esterase activity, a strong acid phosphatase reaction, and a negative immunofluorescence (direct and indirect) against factor VIII antigen. Other cell lines also have been isolated and maintained in culture and present similar characteristics. These cell lines are thought to be derived from the acid-phosphatase-positive marrow stroma directly associated with bone trabecular matrix and probably represent a component of the haemopoietic inductive microenvironment. As such, they may provide a useful tool for studies in vitro of cell interactions and regulatory processes in the control of human bone-marrow haemopoiesis.


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