Design and validation of a clinical instrument for spectral diagnosis of cutaneous malignancy

Eccrine porocarcinoma is a rare aggressive cutaneous malignancy. Complete surgical excision is the standard of care, although there are high rates of local and distant recurrence. We present a unique case of locally recurrent and metastatic subungal porocarcinoma successfully treated with intralesional interleukin-2.

Download Full-text

The Personality Inventory Scales: A Self-Rating Clinical Instrument for Diagnosis of Personality Disorder

Psychological Reports ◽

10.2466/pr0.1991.69.3f.1235 ◽

1991 ◽

Vol 69 (3_suppl) ◽

pp. 1235-1246 ◽

Cited By ~ 2

Author(s):

J. Wesley Burgess

Keyword(s):

Personality Disorders ◽

Diagnostic Interview ◽

Personality Inventory ◽

Personality Structure ◽

Clinical Settings ◽

Everyday Language ◽

Clinical Assessments ◽

Standardized Interview ◽

Test Retest Reliability ◽

Clinical Instrument

A personality inventory was developed as an aid in securing history and beliefs relevant to the assessment of personality structure and the diagnosis of personality disorders. The inventory was developed by restating DSM diagnostic criteria in everyday language, rewording the resulting statements in the form of True/False questions, and placing these questions in a short, self-paced booklet which subjects could complete in about 15 minutes. The following assessments were made and discussed: construct validity, split-half reliability, test-retest reliability, comparison with a standardized interview, and comparison with actual clinical assessments. The personality inventory is discussed as a useful accompaniment to the diagnostic interview in clinical settings and for research into personality structure and personality disorders.

Download Full-text

Outcomes of mohs microgrpahic resection for cutaneous malignancy involving the scrotum

Urologic Oncology Seminars and Original Investigations ◽

10.1016/j.urolonc.2021.05.019 ◽

2021 ◽

Author(s):

Daniel Roberson ◽

Raju Chelluri ◽

Alexander J. Skokan ◽

Leilei Xia ◽

Matthew G. Heavner ◽

...

Keyword(s):

Cutaneous Malignancy

Download Full-text

Sonometric Evaluation of Eustachian Tube Function Using Broadband Stimuli

Annals of Otology Rhinology & Laryngology ◽

10.1177/00034894800890s342 ◽

1980 ◽

Vol 89 (3_suppl) ◽

pp. 178-184 ◽

Cited By ~ 19

Author(s):

Krishna G. Murti ◽

Erdem I. Cantekin ◽

Richard M. Stern ◽

Charles D. Bluestone

Keyword(s):

Eustachian Tube ◽

A Priori ◽

Broadband Noise ◽

Ear Canal ◽

Experimental Conditions ◽

Diagnostic Significance ◽

Tube Function ◽

Series Of Experiments ◽

Sound Conduction ◽

Clinical Instrument

New measurements of acoustical transmission through the eustachian tube (ET) have been obtained in a series of experiments directed toward the development of a clinical instrument to assess ET function behind an intact tympanic membrane (TM). Using a sound conduction method, a sound source was placed in one nostril, and the acoustical energy that was transmitted through the ET was measured by a microphone placed in the ear canal. The present study used a broadband noise as the acoustical stimulus, in contrast to the tonal stimuli employed in previous investigations. This stimulus was chosen because it is believed to reduce the variability in the data due to intersubject differences in the acoustics of the nasopharynx and ET, and to avoid any a priori assumptions concerning the specific frequencies that would be of greatest diagnostic significance. Averaged spectra of the sound transmitted to the ear canal were obtained for three experimental conditions: acoustical source present during subject swallowing, source present with no swallowing, and subject swallowing with source absent. A Bayesian classification scheme based on the statistics of these spectra was used in classifying subjects into one of two possible categories, normal and abnormal ET function. A comparison was made between sonometric classification and classification based on a tympanometric ET function test. Correlation between the two methods was 87.1%.

Download Full-text