scholarly journals Correction: Elevated Snail Expression Mediates Tumor Progression in Areca Quid Chewing-Associated Oral Squamous Cell Carcinoma via Reactive Oxygen Species

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
Author(s):  
Shiuan-Shinn Lee ◽  
Chung-Hung Tsai ◽  
Cheng-Chia Yu ◽  
Yu-Chao Chang
Keyword(s):  
Reactive Oxygen Species ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Tumor Progression ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Snail Expression

A new biosafe reactive oxygen species responsive nanoplatform for targeted oral squamous cell carcinoma therapy

2019 ◽  
Vol 9 (9) ◽  
pp. 1076-1081 ◽  
Author(s):  
Fengying Wang ◽  
Miao Wang ◽  
Lu Zhao ◽  
Qing Li
Keyword(s):  
Reactive Oxygen Species ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
High Stability ◽  
Drug Loading ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Target Cancer

A new reactive oxygen species (ROS)-responsive drug delivery systems (DDSs) needs development and has excellent application prospect. In this study, FA-PEG-TK-PLGA copolymer containing a ROS-responsive TK linker was designed and generated. The polymer self-assembled into stable small-sized DDSs into with hydrophilic PEG shells and hydrophobic PLGA cores, which exhibited high stability in aqueous solutions, besides an adequate drug loading capacity, excellent ROS sensitivity. high stability and good compatibility. Folic acid (FA) in the DDS presented here was used to target cancer cells. The polymer presents great potential as a novel DDSs for Oral squamous cell carcinoma (OSCC) therapy.

Sign in / Sign up

Export Citation Format

Share Document