Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells

PLoS Genetics ◽

10.1371/journal.pgen.1000855 ◽

2010 ◽

Vol 6 (2) ◽

pp. e1000855 ◽

Author(s):

Farjana Fattah ◽

Eu Han Lee ◽

Natalie Weisensel ◽

Yongbao Wang ◽

Natalie Lichter ◽

...

Keyword(s):

Somatic Cells ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Pathway Choice ◽

Break Repair ◽

Non Homologous End Joining

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End-processing nucleases and phosphodiesterases: An elite supporting cast for the non-homologous end joining pathway of DNA double-strand break repair

10.1016/j.dnarep.2016.05.011 ◽

2016 ◽

Vol 43 ◽

pp. 57-68 ◽

Author(s):

Vijay Menon ◽

Lawrence F. Povirk

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

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Stochastic Simulation of DNA Double-Strand Break Repair by Non-homologous End Joining Based on Track Structure Calculations

Radiation Research ◽

10.1667/rr1965.1 ◽

2010 ◽

Vol 173 (5) ◽

pp. 677-688 ◽

Author(s):

Werner Friedland ◽

Peter Jacob ◽

Pavel Kundrát

Keyword(s):

Stochastic Simulation ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Track Structure ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining ◽

Structure Calculations

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DNA Double-Strand Break Repair Through Non-Homologous End-Joining: Recruitment and Assembly of the Players

10.5772/21262 ◽

2011 ◽

Author(s):

Radhika Pankaj ◽

Yoshihisa Matsumoto

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

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Abstract 1352: Inactivation of factors of DNA double-strand break repair by homologous recombination or non-homologous end-joining leads to frequent catastrophic genomic events in murine and human tumors

10.1158/1538-7445.am2018-1352 ◽

2018 ◽

Author(s):

Manasi Ratnaparkhe ◽

John Wong ◽

Pei-Chi Wei ◽

Mario Hlevnjak ◽

Paul Northcott ◽

...

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Human Tumors ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

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Abstract 2561: DNA-PKCS deacetylation by SIRT2 promotes DNA double-strand break repair by non-homologous end joining

10.1158/1538-7445.sabcs18-2561 ◽

2019 ◽

Author(s):

PamelaSara E. Head ◽

Nagaraju P. Ganji ◽

Shi-Ya Wang ◽

Duc Duong ◽

Hui Zhang ◽

...

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

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Non-homologous end-joining protein expression screen from radiosensitive cancer patients yields a novel DNA double strand break repair phenotype

Annals of Translational Medicine ◽

10.21037/atm.2017.03.04 ◽

2017 ◽

Vol 5 (5) ◽

pp. 96-96 ◽

Author(s):

Michael J. McKay ◽

Su Kak Goh ◽

Jeremy N. McKay ◽

Michael Chao ◽

Timothy M. McKay

Keyword(s):

Protein Expression ◽

Cancer Patients ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

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Impairment of the non-homologous end joining and homologous recombination pathways of DNA double strand break repair: Impact on spontaneous and radiation-induced mammary and intestinal tumour risk in Apc mice

10.1016/j.dnarep.2015.08.002 ◽

2015 ◽

Vol 35 ◽

pp. 19-26 ◽

Author(s):

Jackie W. Haines ◽

Margaret Coster ◽

Simon D. Bouffler

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Intestinal Tumour ◽

Radiation Induced ◽

Break Repair ◽

Non Homologous End Joining

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Abstract 2561: DNA-PKCS deacetylation by SIRT2 promotes DNA double-strand break repair by non-homologous end joining

10.1158/1538-7445.am2019-2561 ◽

2019 ◽

Author(s):

PamelaSara E. Head ◽

Nagaraju P. Ganji ◽

Shi-Ya Wang ◽

Duc Duong ◽

Hui Zhang ◽

...

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

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Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

The EMBO Journal ◽

10.1093/emboj/17.18.5497 ◽

1998 ◽

Vol 17 (18) ◽

pp. 5497-5508 ◽

Author(s):

Minoru Takata ◽

Masao S. Sasaki ◽

Eiichiro Sonoda ◽

Ciaran Morrison ◽

Mitsumasa Hashimoto ◽

...

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

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Deficiency of XLF and PAXX prevents DNA double-strand break repair by non-homologous end joining in lymphocytes

10.1080/15384101.2016.1253640 ◽

2017 ◽

Vol 16 (3) ◽

pp. 286-295 ◽

Author(s):

Putzer J. Hung ◽

Bo-Ruei Chen ◽

Rosmy George ◽

Caleb Liberman ◽

Abigail J. Morales ◽

...

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

Download Full-text