scholarly journals Lapatinib, a Dual EGFR and HER2 Tyrosine Kinase Inhibitor, Downregulates Thymidylate Synthase by Inhibiting the Nuclear Translocation of EGFR and HER2

PLoS ONE ◽  
2009 ◽  
Vol 4 (6) ◽  
pp. e5933 ◽  
Author(s):  
Hwang-Phill Kim ◽  
Young-Kwang Yoon ◽  
Jin-Won Kim ◽  
Sae-Won Han ◽  
Hyung-Seok Hur ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Thymidylate Synthase ◽  
Nuclear Translocation ◽  
Kinase Inhibitor ◽  
Her2 Tyrosine Kinase Inhibitor

scholarly journals Role of Hepatic Transporters in the Disposition and Hepatotoxicity of a HER2 Tyrosine Kinase Inhibitor CP-724,714

2009 ◽  
Vol 108 (2) ◽  
pp. 492-500 ◽  
Author(s):  
Bo Feng ◽  
Jinghai J. Xu ◽  
Yi-An Bi ◽  
Rouchelle Mireles ◽  
Ralph Davidson ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Kinase Inhibitor ◽  
Hepatic Transporters ◽  
Her2 Tyrosine Kinase Inhibitor
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