scholarly journals Short-Term Delayed Recall of Auditory Verbal Learning Test Is Equivalent to Long-Term Delayed Recall for Identifying Amnestic Mild Cognitive Impairment

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e51157 ◽  
Author(s):  
Qianhua Zhao ◽  
Yingru Lv ◽  
Yan Zhou ◽  
Zhen Hong ◽  
Qihao Guo
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Verbal Learning ◽  
Amnestic Mild Cognitive Impairment ◽  
Short Term ◽  
Delayed Recall ◽  
Auditory Verbal Learning Test ◽  
Auditory Verbal Learning ◽  
Learning Test

scholarly journals Normative Data that Does Not Exclude Participants with Mild Cognitive Impairment Results in Lower Than Expected Memory Impairment Rates, Particularly in Females

2019 ◽  
Vol 34 (6) ◽  
pp. 848-848
Author(s):  
N Stricker ◽  
E Lundt ◽  
T Christianson ◽  
M Machulda ◽  
W Kremers ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Aging ◽  
Normative Data ◽  
Verbal Learning ◽  
Population Based ◽  
Delayed Recall ◽  
Impaired Performance ◽  
Auditory Verbal Learning ◽  
Learning Test

Abstract Objective Mayo’s Older Adult Normative Studies (MOANS) have served as an important resource for clinicians for three decades. Data collection was completed prior to the development and widespread use of Mild Cognitive Impairment (MCI) as a construct. Therefore, a portion of individuals included in the MOANS normative studies likely had undetected cognitive impairment. Method The Mayo Clinic Study of Aging (MCSA) is a population-based study of cognitive aging among Olmsted County, Minnesota, residents that began in October 2004. We applied age-adjusted MOANS norms (Ivnik et al., 1992) for the Auditory Verbal Learning Test (AVLT) long delay recall to cognitively unimpaired participants age 56 or older in the MCSA (N = 3,603). We used 1-sample tests of proportions comparing observed impairment rates to impairment rates expected based on a normal distribution of performance. Results Results showed that a significantly lower than expected number of participants demonstrated impaired delayed recall based on MOANS norms (all p’s < .001). Using a lenient cut-off (< -1 SD), only 7.3% of participants demonstrated impaired performance (vs. 15.9% expected), and this was more pronounced for females (3.5% impaired) relative to males (11.1% impaired). Further, only 0.6% of participants demonstrated impaired performance at a cut-off of < -2 SD, and no participants aged 80-91 reached this cut-off (2.3% expected). Conclusions Results suggest that the sensitivity of the original MOANS norms is lowered by likely inclusion of individuals with MCI, particularly in females. Updated normative data for the AVLT that exclude individuals with MCI and adjust for sex are needed.

scholarly journals The Brain Metabolic Correlates of the Main Indices of Neuropsychological Assessment in Alzheimer’s Disease

2020 ◽  
Vol 10 (2) ◽  
pp. 25 ◽  
Author(s):  
Agostino Chiaravalloti ◽  
Maria Ricci ◽  
Daniele Di Biagio ◽  
Luca Filippi ◽  
Alessandro Martorana ◽  
...  
Keyword(s):  
Neuropsychological Assessment ◽  
Verbal Learning ◽  
Delayed Recall ◽  
Auditory Verbal Learning Test ◽  
Fdg Uptake ◽  
Complex Figure ◽  
Auditory Verbal Learning ◽  
18F Fdg ◽  
Learning Test ◽  
Figure Test

Background: The study aimed to investigate the relationships between F-18 fluorodeoxyglucose (18F)FDG uptake and neuropsychological assessment in Alzheimer’s disease (AD). Methods: We evaluated 116 subjects with AD according to the NINCDS-ADRDA criteria. All the subjects underwent a brain PET/CT with (18F)FDG, cerebrospinal fluid (CSF) assay, mini-mental state examination (MMSE) and further neuropsychological tests: Rey auditory verbal learning test, immediate recall (RAVLT immediate); Rey auditory verbal learning test, delayed recall (RAVLT, delayed); Rey complex figure test, copy (RCFT, copy); Rey complex figure test, delayed recall (RCFT, delayed); Raven’s colored progressive matrices (RCPM); phonological word fluency test (PWF) and Stroop test. We performed the statistical analysis by using statistical parametric mapping (SPM12; Wellcome Department of Cognitive Neurology, London, UK). Results: A significant relationship has been reported between (18F)FDG uptake and RAVLT immediate test in Brodmann area (BA)37 and BA22 and with RCFT, copy in BA40, and BA7. We did not find any significant relationships with other tests. Conclusion: In the AD population, brain (18F)FDG uptake is moderately related to the neuropsychological assessment, suggesting a limited impact on statistical data analysis of glucose brain metabolism.

P1-520: CORRELATIONS BETWEEN REY AUDITORY VERBAL LEARNING TEST (AVLT) AND UPPER EXTREMITY DUAL TASK FUNCTION IN DETECTING COGNITIVE IMPAIRMENT

2006 ◽  
Vol 14 (7S_Part_9) ◽  
pp. P530-P531
Author(s):  
Edward Zamrini ◽  
Sarah Fakhoury ◽  
Daniel Gaytan-Jenkins ◽  
Anthony Lopez ◽  
Hossein Ehsani ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Upper Extremity ◽  
Dual Task ◽  
Verbal Learning ◽  
Auditory Verbal Learning Test ◽  
Auditory Verbal Learning ◽  
Learning Test

scholarly journals Prevalence, Cognitive Characteristics and Influence Factors of Amnestic Mild Cognitive Impairment among Community-dwelling Older Adults in Chengdu, China

2021 ◽  
Author(s):  
Peiyuan Qiu ◽  
Yan Cai ◽  
Yangyang Wang ◽  
Shiyi Liao ◽  
Yunbo Nie ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Multiple Logistic Regression Analysis ◽  
Amnestic Mild Cognitive Impairment ◽  
Multiple Logistic Regression ◽  
Delayed Recall ◽  
Cognitive Characteristics

Abstract Background: Dementia is a global public health priority. Mild cognitive impairment (MCI) is a transitional stage between normal aging and dementia. And amnestic MCI (aMCI) is proved to have a higher probability to develop into AD comparing to other type of MCI. Yet a few studies have focused on prevalence of aMCI in China. This study aims to explore the prevalence of amnestic mild cognitive impairment (aMCI), cognitive characteristics of aMCI, and associated risk factors for aMCI.Methods: A cross-sectional study was conducted in the communities of Chengdu, China. Participants were 368 older adults aged 60 years and over. Participants completed various neuropsychological assessments, including the Mini-Mental State Examination (MMSE), the Clinical Dementia Rating (CDR), Auditory Verbal Learning Test (AVLT), Wechsler’s Logical Memory Task (LMT), Boston Naming Test (BNT) and Trail Making Test Part A (TMT-A). Social information was collected by standard questionnaire. Multiple logistic regression analysis was utilized to screen for the risk and protective factors of aMCI.Results: Data included 309 subjects with normal cognitive function and 59 with aMCI. The prevalence of aMCI was 16.0%.The average age of participants was 69.06±7.30 years, with 56.0% being females. After controlling for age, gender and education, the Spearman partial correlation coefficient between diverse cognitive assessments and aMCI ranged from -0.52 for the long-term delayed recall scores in AVLT to 0.19 for the time-usage scores in TMT-A, and results revealed that all domains except naming scores (after semantic cue of BNT) and error quantity (in TMT-A) showed statistically significant associations with aMCI. And the results of multiple logistic regression analysis indicated that older age (OR=1.044, 95%CI: 1.002~1.087, p=0.042), lower educational level, and diabetes (OR=2.450, 95%CI: 1.246~4.818, p=0.009) were risk factors of aMCI.Conclusions: Participants with aMCI showed lower cognitive function in memory, language and executive domains, especially in long-term delayed recall. The participants who were older, had less education, or with diabetes had higher risk of suffering from aMCI. These results may help clinical practitioners design and conduct targeted cognitive training and chronic disease management for the elderly, aiming to prevent and delay development of Alzheimer’s dementia.

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