scholarly journals The Brain Metabolic Correlates of the Main Indices of Neuropsychological Assessment in Alzheimer’s Disease

2020 ◽  
Vol 10 (2) ◽  
pp. 25 ◽  
Author(s):  
Agostino Chiaravalloti ◽  
Maria Ricci ◽  
Daniele Di Biagio ◽  
Luca Filippi ◽  
Alessandro Martorana ◽  
...  

Background: The study aimed to investigate the relationships between F-18 fluorodeoxyglucose (18F)FDG uptake and neuropsychological assessment in Alzheimer’s disease (AD). Methods: We evaluated 116 subjects with AD according to the NINCDS-ADRDA criteria. All the subjects underwent a brain PET/CT with (18F)FDG, cerebrospinal fluid (CSF) assay, mini-mental state examination (MMSE) and further neuropsychological tests: Rey auditory verbal learning test, immediate recall (RAVLT immediate); Rey auditory verbal learning test, delayed recall (RAVLT, delayed); Rey complex figure test, copy (RCFT, copy); Rey complex figure test, delayed recall (RCFT, delayed); Raven’s colored progressive matrices (RCPM); phonological word fluency test (PWF) and Stroop test. We performed the statistical analysis by using statistical parametric mapping (SPM12; Wellcome Department of Cognitive Neurology, London, UK). Results: A significant relationship has been reported between (18F)FDG uptake and RAVLT immediate test in Brodmann area (BA)37 and BA22 and with RCFT, copy in BA40, and BA7. We did not find any significant relationships with other tests. Conclusion: In the AD population, brain (18F)FDG uptake is moderately related to the neuropsychological assessment, suggesting a limited impact on statistical data analysis of glucose brain metabolism.

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Pukovisa Prawiroharjo ◽  
Hainah Ellydar ◽  
Peter Pratama ◽  
Rizki Edmi Edison ◽  
Sitti Evangeline Imelda Suaidy ◽  
...  

We aimed to find the differences in memory capabilities between pornography-addicted and nonaddicted juveniles. We enrolled 30 juveniles (12–16 y) consisting of 15 pornography addiction and 15 nonaddiction subjects. We used Rey Auditory Verbal Learning Test (RAVLT) to measure verbal memory, Rey–Osterrieth Complex Figure Test (ROCFT) for visual memory, along with Trail Making Test A and B (TMT-A and TMT-B) for attention. We found a significant reduction in the RAVLT A6 result of the addiction group (nonaddiction vs addiction: 13.47 ± 2.00 vs 11.67 ± 2.44, MD = −1.80, p=0.04), but not in ROCFT or attention tests. Analysis in sex subgroups yielded no sex-specific difference. We concluded that pornography addiction may be associated with impaired recent verbal memory in juveniles, regardless of sex and without association to attention.


GeroPsych ◽  
2017 ◽  
Vol 30 (2) ◽  
pp. 79-84 ◽  
Author(s):  
Bridget Burmester ◽  
Janet Leathem ◽  
Paul Merrick

Abstract. Evidence regarding the relationship between subjective memory complaints (SMCs) and objective memory functioning remains mixed; assessment methods may underlie this inconsistency. In this study, 94 participants aged 40 and above completed two measures of SMCs (open-ended self-reports, and a questionnaire) and memory tests (Rey Auditory Verbal Learning Test and Rey Complex Figure Test). Canonical correlation analysis showed no significant associations between any measures of memory and SMCs, regardless of the assessment method employed. Possible explanations for this result and the influence of study limitations are discussed.


Author(s):  
Selene G Vicente ◽  
Daniela Ramos-Usuga ◽  
Fernando Barbosa ◽  
Nuno Gaspar ◽  
Artemisa R Dores ◽  
...  

Abstract Objective The principal goal of this study was to produce adjusted normative data for European Portuguese native speakers from Portugal on 2 neuropsychological tests widely used to assess learning and memory: the Hopkins Verbal Learning Test-Revised (HVLT-R) and the Rey–Osterrieth Complex Figure Test (ROCF). Method The study included 300 individuals aged 18–92 years (M = 50.4, SD = 21.2), who had educational backgrounds ranging from 3 to 25 years (M = 10.4, SD = 5.2). Results Age, education, and sex were significantly associated with HVLT-R and ROCF performance. These demographic variables accounted for 61% of the variance in HVLT-R total recall, 54% in HVLT-R delayed recall, 18% in HVLT-R recognition, 55% in ROCF copy, and 39% in ROCF immediate recall. Conclusions The normative data are presented as regression-based algorithms to adjust direct and derived test scores for age, education, and sex. This study provides a calculator of normative data derived from the results of the regression models.


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