scholarly journals Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex

PLoS ONE ◽  
2013 ◽  
Vol 8 (2) ◽  
pp. e57445 ◽  
Author(s):  
Bo Zhang ◽  
Sharon S. McDaniel ◽  
Nicholas R. Rensing ◽  
Michael Wong
Keyword(s):  
Mouse Model ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Mtor Pathway ◽  
Pathway Activation

scholarly journals Therapeutic Trial of Metformin and Bortezomib in a Mouse Model of Tuberous Sclerosis Complex (TSC)

PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e31900 ◽  
Author(s):  
Neil Auricchio ◽  
Izabela Malinowska ◽  
Reuben Shaw ◽  
Brendan D. Manning ◽  
David J. Kwiatkowski
Keyword(s):  
Mouse Model ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Therapeutic Trial

scholarly journals Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex

2018 ◽  
Vol 27 (12) ◽  
pp. 2113-2124 ◽  
Author(s):  
James McKenna ◽  
David Kapfhamer ◽  
Jason M Kinchen ◽  
Brandi Wasek ◽  
Matthew Dunworth ◽  
...  
Keyword(s):  
Mouse Model ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Polyamine Metabolism

scholarly journals The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex

2012 ◽  
Vol 21 (14) ◽  
pp. 3226-3236 ◽  
Author(s):  
Sharon W. Way ◽  
Natalia S. Rozas ◽  
Henry C. Wu ◽  
James McKenna ◽  
R. Michelle Reith ◽  
...  
Keyword(s):  
Mouse Model ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Differential Effects

Early developmental electroencephalography abnormalities, neonatal seizures, and induced spasms in a mouse model of tuberous sclerosis complex

Epilepsia ◽  
2020 ◽  
Vol 61 (5) ◽  
pp. 879-891 ◽  
Author(s):  
Nicholas Rensing ◽  
Kevin J. Johnson ◽  
Thomas J. Foutz ◽  
Joseph L. Friedman ◽  
Rafael Galindo ◽  
...  
Keyword(s):  
Mouse Model ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Neonatal Seizures ◽  
Early Developmental
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