scholarly journals Antioxidants Abrogate Alpha-Tocopherylquinone-Mediated Down-Regulation of the Androgen Receptor in Androgen-Responsive Prostate Cancer Cells

PLoS ONE ◽  
2016 ◽  
Vol 11 (3) ◽  
pp. e0151525 ◽  
Author(s):  
Alexandra M. Fajardo ◽  
Debra A. MacKenzie ◽  
Sarah L. Olguin ◽  
John K. Scariano ◽  
Ian Rabinowitz ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Down Regulation

Down-Regulation of the Androgen Receptor by G-Quadruplex Ligands Sensitizes Castration-Resistant Prostate Cancer Cells to Enzalutamide

2018 ◽  
Vol 61 (19) ◽  
pp. 8625-8638 ◽  
Author(s):  
Martina Tassinari ◽  
Graziella Cimino-Reale ◽  
Matteo Nadai ◽  
Filippo Doria ◽  
Elena Butovskaya ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Cells ◽  
Castration Resistant Prostate Cancer ◽  
Prostate Cancer Cells ◽  
Down Regulation ◽  
Castration Resistant ◽  
G Quadruplex

scholarly journals Walnut polyphenol metabolites, urolithins A and B, inhibit the expression of the prostate-specific antigen and the androgen receptor in prostate cancer cells

2014 ◽  
Vol 5 (11) ◽  
pp. 2922-2930 ◽  
Author(s):  
Claudia Sánchez-González ◽  
Carlos J. Ciudad ◽  
Véronique Noé ◽  
Maria Izquierdo-Pulido
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Cells ◽  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Prostate Cancer Cells ◽  
Down Regulation

Urolithins attenuate the function of the AR by repressing its expression, causing a down-regulation of PSA levels and inducing apoptosis. Our results suggest that a diet rich in ellagitannins could contribute to the prevention of prostate cancer.

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