scholarly journals Effects of acute administration of donepezil or memantine on sleep-deprivation-induced spatial memory deficit in young and aged non-human primate grey mouse lemurs (Microcebus murinus)

PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0184822 ◽  
Author(s):  
Anisur Rahman ◽  
Yves Lamberty ◽  
Esther Schenker ◽  
Massimo Cella ◽  
Solène Languille ◽  
...  
Author(s):  
Kun Niu ◽  
Jia-Lin Qin ◽  
Guo-Fang Lu ◽  
Jian Guo ◽  
John P. Williams ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Clara Hozer ◽  
Martine Perret ◽  
Samuel Pavard ◽  
Fabien Pifferi

Abstract Circadian rhythms are ubiquitous attributes across living organisms and allow the coordination of internal biological functions with optimal phases of the environment, suggesting a significant adaptive advantage. The endogenous period called tau lies close to 24 h and is thought to be implicated in individuals’ fitness: according to the circadian resonance theory, fitness is reduced when tau gets far from 24 h. In this study, we measured the endogenous period of 142 mouse lemurs (Microcebus murinus), and analyzed how it is related to their survival. We found different effects according to sex and season. No impact of tau on mortality was found in females. However, in males, the deviation of tau from 24 h substantially correlates with an increase in mortality, particularly during the inactive season (winter). These results, comparable to other observations in mice or drosophila, show that captive gray mouse lemurs enjoy better fitness when their circadian period closely matches the environmental periodicity. In addition to their deep implications in health and aging research, these results raise further ecological and evolutionary issues regarding the relationships between fitness and circadian clock.


2019 ◽  
Vol 129 (5) ◽  
pp. 1365-1373 ◽  
Author(s):  
Gregory A. Chinn ◽  
Jennifer M. Sasaki Russell ◽  
Esther T. Banh ◽  
Saehee C. Lee ◽  
Jeffrey W. Sall

Metallomics ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 144-153
Author(s):  
Ladan Behzadfar ◽  
Shokoufeh Hassani ◽  
Hossein Feizpour ◽  
Nakisa Abbasian ◽  
Armin Salek Maghsoudi ◽  
...  

Mercury is a highly poisonous heavy metal abundantly found in the environment in its inorganic form.


2002 ◽  
Vol 128 (1-3) ◽  
pp. 107-115 ◽  
Author(s):  
R Carney ◽  
C Dardis ◽  
W.K Cullen ◽  
V Felipo ◽  
R Anwyl ◽  
...  

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